Determinants of genital human papillomavirus infection among cytologically normal women attending the University of New Mexico student health center

OBJECTIVES: To confirm the risk factors for genital human papillomavirus (HPV) infection. GOAL OF THIS STUDY: To investigate risk factors for HPV detection apart from the correlated risk factors for cervical neoplasia. STUDY DESIGN: Cervical human papillomavirus (HPV) DNA was assessed in 357 cytologically normal women attending the University of New Mexico student health center. Cervical swab samples were obtained for HPV DNA detection and typing using a PCR-based DNA amplification system. Possible determinants of cervical HPV were examined including age, ethnicity, history of sexually transmitted disease, oral contraceptive use, smoking, age at first intercourse, lifetime number of sex partners, marital status, and history of pregnancy. RESULTS: A 44.3% overall prevalence of cervical HPV was observed. On univariate analysis, factors associated with increasing HPV prevalence included higher lifetime number of sex partners and single marital status. After adjustment for potential confounding variables, we found that HPV prevalence increased with higher lifetime number of sexual partners. CONCLUSION: These findings, along with those from the companion reports in this issue of the journal, support the sexual route of transmission of the virus.     

Reconstruction of three-dimensional objects through matching oftheir parts

The problem of re-assembling an object from its parts or fragments has never been addressed with a unified computational approach, which depends on the pure geometric form of the parts and not on application-specific features. We propose a method for the automatic reconstruction of a model based on the geometry of its parts, which may be computer-generated models or range-scanned models. The matching process can benefit from any other external constraint imposed by the specific application     

Prediction of Experimental Methanol Decomposition Rates on Platinum from First Principles

A microkinetic model for methanol decomposition on platinum is presented. The model incorporates competitive decomposition pathways, beginning with both O–H and C–H bond scission in methanol, and uses results from density functional theory (DFT) calculations [Greeley and Mavrikakis, J. Am. Chem. Soc. 124 (2002) 7193, Greeley and Mavrikakis, J. Am. Chem. Soc. 126 (2004) 3910]. Results from reaction kinetics experiments show that the rate of H₂ production increases with increasing temperature and methanol concentration in the feed and is only nominally affected by the presence of CO or H₂ with methanol. The model, based on the values of binding energies, pre-exponential factors and activation energy barriers derived from first principles calculations, accurately predicts experimental reaction rates and orders. The model also gives insight into the most favorable reaction pathway, the rate-limiting step, the apparent activation energy, coverages, and the effects of pressure. It is found that the pathway beginning with the C–H bond scission (CH₃OH→H₂COH→HCOH→CO) is dominant compared with the path beginning with O–H bond scission. The cleavage of the first C–H bond in methanol is the rate-controlling step. The surface is highly poisoned by CO, whereas COH appears to be a spectator species.     

Microblog language identification: overcoming the limitations of short, unedited and idiomatic text

Multilingual posts can potentially affect the outcomes of content analysis on microblog platforms. To this end, language identification can provide a monolingual set of content for analysis. We find the unedited and idiomatic language of microblogs to be challenging for state-of-the-art language identification methods. To account for this, we identify five microblog characteristics that can help in language identification: the language profile of the blogger (blogger), the content of an attached hyperlink (link), the language profile of other users mentioned (mention) in the post, the language profile of a tag (tag), and the language of the original post (conversation), if the post we examine is a reply. Further, we present methods that combine these priors in a post-dependent and post-independent way. We present test results on 1,000 posts from five languages (Dutch, English, French, German, and Spanish), which show that our priors improve accuracy by 5 % over a domain specific baseline, and show that post-dependent combination of the priors achieves the best performance. When suitable training data does not exist, our methods still outperform a domain unspecific baseline. We conclude with an examination of the language distribution of a million tweets, along with temporal analysis, the usage of twitter features across languages, and a correlation study between classifications made and geo-location and language metadata fields.     

Inverse lighting design using a coverage optimization strategy

Lighting design is an essential process in computer cinematography, games, architectural design and various other applications for correctly illuminating or highlighting parts of a scene and enhancing storytelling. When targeting specific illumination goals and constraints, this process can be tedious and counter-intuitive even for experienced users and thus automatic, goal-driven methods have emerged for the estimation of a lighting configuration to match the desired result. We present a general automatic approach to such an inverse lighting design problem, where the number of light sources along with their position and emittance are computed given a set of user-specified lighting goals. To this end, we employ a special hierarchical light clustering that operates in the lighting goal coverage domain and overcomes limitations of previous approaches in environments with high occlusion or structural complexity. Our approach is independent of the underlying light transport model and can quickly converge to usable solutions. We validate our results and provide comparative evaluation with the current state of the art.     

Building Agile Systems with Mobile Code

Mobile code has been championed as a solution to a plethora of software problems. This paper describes investigative work undertaken in order to evaluate the mobile code abstractions of Mobile Agents and Mobile Objects, and to understand the implications of using these abstractions to build distributed systems.We describe two systems built to support the Sales Order Process of a distributed manufacturing enterprise, using IBM's Aglets Software Development Kit. The Sales Order Process model and the requirements for agility used as the basis for these implementations are derived from data collected in an industrial case study.Both systems are evaluated using the Goal/Question/Metric methodology. Two new metrics for Semantic Alignment and Change Capability are presented and used to evaluate each system with respect to the degree of system agility supported. The systems are evaluated through a set of scenarios generated during the case study in an attempt to see if they support system integration and agility in the manufacturing domain. Further we examine the implications of using a mobile code abstraction when compared with the abstraction offered by traditional distribution technology.The work described provides evidence that both Mobile Agent and Mobile Object systems have inherent properties that can be used to build agile distributed systems. Further, Mobile Agents with their additional autonomy provide marginally greater support.     

Efficient On-Line Frequency Allocation and Call Control in Cellular Networks

In this paper we consider communication issues arising in cellular (mobile) networks that utilize frequency division multiplexing (FDM) technology. In such networks, many users within the same geographical region can communicate simultaneously with other users of the network using distinct frequencies. The spectrum of available frequencies is limited; thus, efficient solutions to the frequency-allocation and the call-control problems are essential. In the frequency-allocation problem, given users that wish to communicate, the objective is to minimize the required spectrum of frequencies so that communication can be established without signal interference. The objective of the call-control problem is, given a spectrum of available frequencies and users that wish to communicate, to maximize the number of users served. We consider cellular, planar, and arbitrary network topologies. In particular, we study the on-line version of both problems using competitive analysis. For frequency allocation in cellular networks, we improve the best known competitive ratio upper bound of 3 achieved by the folklore Fixed Allocation algorithm, by presenting an almost tight competitive analysis for the greedy algorithm; we prove that its competitive ratio is between 2.429 and 2.5 . For the call-control problem, we present the first randomized algorithm that beats the deterministic lower bound of 3 achieving a competitive ratio between 2.469 and 2.651 for cellular networks. Our analysis has interesting extensions to arbitrary networks. Also, using Yao's Minimax Principle, we prove two lower bounds of 1.857 and 2.086 on the competitive ratio of randomized call-control algorithms for cellular and arbitrary planar networks, respectively.     

Scanning tunnelling microscopy of tobacco mosaic virus on evaporated and sputter-coated palladium/gold substrates

We present scanning tunnelling microscope (STM) images of untreated tobacco mosaic virus (TMV) deposited on thermally evaporated and on sputter-coated palladium/gold 40:60 (Pd/Au) substrates, and imaged under ordinary atmospheric conditions. The TMV imaged on both evaporated and sputter-coated substrates was consistently several times wider than the known diameter of the virus. TMV on evaporated Pd/Au became overcoated with Pd/Au material during sample preparation and appeared elevated in STM images, whereas TMV on sputter-coated Pd/Au appeared as depressions. When naked TMV were intentionally overcoated with Pd/Au, the STM images were found to be similar to those for TMV on evaporated Pd/Au.