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排序方式: 共有114条查询结果,搜索用时 15 毫秒
1.
Applications of large-scale computer modeling and simulation to a class of bioelectric field problems in a variety of biomedical research areas, from single cells to full human structures, are described. The authors focus on a specific subset of bioelectric field problems that have applications in electrocardiography and electroencephalography. The physics and physiology of bioelectric volume conductors are introduced. A specific computational example and the authors' view on the future direction of computational medicine are presented 相似文献
2.
In this paper, we discuss the problem of quality control with an unreliable machine which produces defects at a rate of Λ0, per unit when in-control and a rate of Lambda; 1, when out-of-control (where Λ1 Λ 0). Every h time periods, we sample n units, count the number of defects, and (using a process based on a Shewart c-chart) test the hypothesis that the machine is in control by comparing the total number of defects to an upper control limit (UCL). More important, we introduce the concept that a buffer inventory which immediately follows the unreliable machine may reduce expected total costs. This buffer serves to delay the movement of items from the unreliable machine to the next stage of the production process. In this way, we can isolate and repair most defective items before they are embedded in a product downstream or sold to customers where repair is more costly. To search for the optimal control policy, we find bounds for n, h, and UCL; given values for these variables, we show how the optimal buffer size can be determined directly. Numerical results illustrate the magnitude of potential savings. 相似文献
3.
G. A. Turner J. R. Matheson G.‐Z. Li X.‐Q. Fei D. Zhu F. L. Baines 《International journal of cosmetic science》2013,35(1):78-83
Dandruff is a common complaint and is suffered by as much as half of the population at some time post puberty. The condition is characterized by the presence of flakes on the scalp and in the hair, and is often accompanied by itch. The most common treatment for dandruff is the use of shampoo formulations that contain fungistatic agents such as zinc pyrithione (ZPT) and octopirox. Whilst most antidandruff shampoos are effective in resolving the symptoms of dandruff these shampoos can often result in hair condition that is less than acceptable to consumers which can lead to a tendency for them to revert to use of a non‐antidandruff shampoo. This can result in a rapid return of dandruff symptoms. The aim of this investigation was to study the impact of using a combination of antidandruff actives and silicones on the resolution of dandruff and to deliver superior sensory properties to the hair. We have demonstrated that shampoo containing the dual active system of ZPT/Climbazole deposits both active agents onto a model skin surface (VitroSkin) and reduces Malassezia furfur regrowth in vitro. Clinical evaluation of the dual active shampoo demonstrated superior efficacy and retained superiority during a regression phase where all subjects reverted to using a non‐antidandruff shampoo. We have also demonstrated that it is possible to deposit silicone materials from antidandruff shampoo uniformly over both virgin and damaged hair fibres that results in smoother hair fibres (as evidenced by reduced dry friction). This combination of antidandruff agents and conditioning silicones delivered from a shampoo provides subjects with superior antidandruff efficacy and desired end sensory benefits ensuring compliance and longer term dandruff removal. 相似文献
4.
K. Lee Matheson Ted P. Matson Kang Yang 《Journal of the American Oil Chemists' Society》1986,63(3):365-370
A peaked ethylene oxide distribution alcohol ethoxylate can be produced using new catalyst systems. The mechanism of ethoxylation
is discussed. Such Novel™ ethoxylates are markedly different from a conventional ethoxylate in physical properties and performance
characteristics. Performance and formulation studies show several advantages for the peaked distribution in typical household
product formulations.
Presented at the AOCS meeting in Dallas, May 1984.
Deceased. 相似文献
5.
Phenyl isomer distributions, within current commercial limits of HF and A1C13 linear alkylbenzene sulfonates (LAS), have little effect on dishwashing performance in light-duty liquids (LDL), detergency performance in heavy-duty powders (HDP), and interfacial tension value. The most important factor in determining performance differences among commercial LAS samples is carbon chain homolog distribution. Both HF and A1C13 LAS perform equally well and can be used interchangeably in high-performance products. The optimum for foam stability in light-duty liquids shifts towards shorter alkyl chain length as water hardness increases. At 0 ppm water hardness the optimum occurs at C13: at 50–150 ppm the optimum moves to C11 and C12; and above 150 ppm the optimum shifts to include C10, C11 and C,12. The detergency performance optimum range in a phosphate built heavy-duty powder at 50 and 150 ppm water hardness includes the C12, C13 and C14 alkyl chain lengths. In a nonphosphate built powder the optimum is similar at 50 ppm hardness to that of a phosphate built powder, but shifts at 150 ppm hardness to include C11, C12 and C13. 相似文献
6.
RT Matheson DR Miller MJ Lacombe YN Han S Iwanaga H Kato KD wuepper 《Canadian Metallurgical Quarterly》1976,58(6):1395-1406
Flaujeac trait is the functional deficiency of a plasma protein of the intrinsic coagulation, kinin-forming, and plasma fibrinolytic pathways. The Flaujeac factor in man has been isolated and tentatively identified as a kininogen of high molecular weight (HMW). Highly purified bovine HMW-kininogen, but not bovine low molecular weight kininogen, repaired Flaujeac factor deficiency. The two subspecies of this molecule, HMW-kininogen a and HMW-kininogen b, also corrected Flaujeac factor deficiency. When bovine HMW-kininogen was incubated with bovine plasma kallikrein, kinin-free HMW-kininogen, bradykinin, and a glycopeptide fragment (peptide 1-2; 12,584 daltons) were rapidly released. None of these fragmentation products corrected Flaujeac factor deficiency alone or in mixtures. The function of HMW-kininogen appeared to depend upon the structural integrity of the native molecule. When injected in concentrations of 2 pmol-8 nmol/0.1 ml, peptide 1-2 caused increased vascular permeability in rabbits, rats, or guinea pigs. The enhanced permeability was maximal within 1-2 min and terminated in 5-10 min, differing from that of bradykinin or histamine. Injected together in equimolar amounts, peptide 1-2 and bradykinin produced a synergistic permeability response which was immediate in onset as well as prolonged in duration. Peptide 1-2 is a rapidly acting, highly basic glyco-peptide which mediates increased vascular permeability in a complementary and synergistic manner with bradykinin. 相似文献
7.
Techniques are presented for designing fixed-tuned millimetre-wave components with the least number of parts to minimise the cost and maximise the potential for volume manufacture. Design techniques for millimeter-wave mixer components targeted at potentially high volume applications, such as medical and security screening and nondestructive testing, require certain compromises in the use of CAD tools. The compromise techniques are demonstrated using commercially available foundry diodes in the design of a 183 GHz subharmonic mixer for earth observation applications. The resulting mixer exhibits 6.85 dB double sideband conversion loss and a mixer temperature of 988 K using 5 mW of local oscillator power at 92 GHz 相似文献
8.
D. Maier N. Kämpfer J. de la Noë W. Amacher A. Barcia P. Baron B. Barry G. Beaudin J. Cernicharo B. Ellison J.-D. Gallego M. Gustafsson A. Karpov U. Klein K. Künzi J. Louhi J. Mallat D. Matheson J.-R. Pardo R. Peter A.V. Räisänen P. Ricaud R. Siddans C. Viguerie M. Wüthrich 《Journal of Infrared, Millimeter and Terahertz Waves》2001,22(11):1555-1575
EMCOR is a heterodyne receiver for the frequency range of 201 to 210 GHz. It has been designed for ground-based measurements of various minor constituents of the stratosphere involved in ozone chemistry. Since the aim was the detection of faint spectral lines, a superconducting tunnel junction has been chosen as mixer element and special care has been taken in developing the calibration unit of the system. The front-end is completed by a quasi-optical system, a solid state local oscillator with electronic tuning and a HEMT pre-amplifier. In the back-end an acousto-optical spectrometer is employed to analyse the signal. A PC controls the whole system. The instrument has been installed at a high mountain site in the Swiss Alps. 相似文献
9.
10.
Bennett CM Dharmage SC Matheson M Gras JL Markos J Mészáros D Hopper J Walters EH Abramson MJ 《The Science of the total environment》2010,409(2):294-299
Wood smoke exposure has been associated with adverse respiratory health outcomes, with much of the current research focused on wood smoke from domestic heating and cooking. This study examined the association between respiratory symptoms and outdoor wood smoke in Launceston, Tasmania, where ~ 30% of homes use wood burners for domestic heating. This ecological study examined data from participants of the 2004 Tasmanian Longitudinal Health Study postal survey and compared the prevalence of respiratory symptoms in Launceston (n = 601) with that in Hobart (n = 1071), a larger Tasmanian city with much less wood smoke. Multivariate logistic regression models were used to investigate the associations of interest while adjusting for gender, atopy, history of allergic disease and current smoking status. There were no significant differences in symptom prevalence between Launceston and Hobart. Two subgroup analyses, which examined participants with pre-existing chronic respiratory disease, and those who reported actively using a wood burner in their home, also did not find significant differences. Any impact of wood smoke on non-specific respiratory symptoms might have been overshadowed by other important determinants of respiratory health, such as vehicle exhaust and tobacco smoking, or were too small to have been detected. However, the lack of detectable differences in symptom prevalence might also reflect the success of regulatory action by local governments to reduce wood smoke emissions in Launceston. The results of other epidemiological studies support an association between ambient wood smoke exposure and adverse respiratory health. Further investigations of wood smoke exposure in Australian settings are needed to investigate the lack of significant associations found in this study, especially studies of indoor air quality and health impacts in children and elderly populations. 相似文献