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1.
Numerical prediction of fraction of eutectic phase in Sn−Ag−Cu soldring using the phase-field method
Machiko Ode Minoru Ueshima Taichi Abe Hideyuki Murakami Hidehiro Onodera 《Journal of Electronic Materials》2006,35(11):1969-1974
A combination of macroscale solidification simulation and phase-field calculation is employed to predict the volume fraction
of the eutectic phase in Sn-4.0 mass% Ag-XCu solder alloys (X=0.5–1.1 mass%). The solidification simulation incorporates the
cooling rate in the phase-field simulation. We assume the residual liquid solidifies as eutectic phase when the driving force
for the nucleation of Cu6Sn5 amounts to a critical value, which is determined based on the experimental data. Though the calculation results depend on
the experimental data, the obtained fractions are about 40% for 0.5 mass% Cu and more than 90% for 1.1 mass% Cu alloy, which
shows good agreement with the experimental data. 相似文献
2.
T Nishida TP Huang A Seiyama E Hamada W Kamiike S Ueshima H Kazuo H Matsuda 《Canadian Metallurgical Quarterly》1998,115(2):412-420
BACKGROUND & AIMS: Endothelin 1 is considered to be an important regulator of sinusoidal blood flow and increases during endotoxemia. The purpose of this study was to investigate the role of endothelin 1 in hepatic microcirculation, oxygen transport, and liver injury during endotoxemia. METHODS: Male Sprague-Dawley rats were continuously infused with 2.5 mL/h of saline, 0.8 mg . kg-1 . h-1 of lipopolysaccharide (LPS), 3 mg . kg-1 . h-1 of BQ-485, an endothelin A-receptor antagonist, or LPS plus BQ-485 for 7 hours. RESULTS: BQ-485 infusion had no significant effect on hepatic microcirculation and liver injury. LPS increased the plasma levels of aspartate aminotransferase (AST) and total bilirubin and decreased the hepatic adenosine triphosphate (ATP) level and bile flow rate. LPS + BQ-485 infusion further increased the plasma levels of AST and total bilirubin and decreased the bile flow rate and the hepatic ATP level. Dual-spot microspectroscopy revealed mild decreases in sinusoidal erythrocyte velocity and oxygen transport in the LPS group and profound decreases in these parameters in the LPS + BQ-485 group. Histological examinations revealed massive necrotic changes in the pericentral regions of the LPS + BQ-485 group. CONCLUSIONS: These results suggest that blockade of endothelin A receptors disturbs hepatic microcirculation and oxygen transport and aggravates the necrotic injury induced by endotoxin. 相似文献
3.
Hiroaki Inoue Yuji Arai Tsunao Kishida Ryu Terauchi Kuniaki Honjo Shuji Nakagawa Shinji Tsuchida Tomohiro Matsuki Keiichirou Ueshima Hiroyoshi Fujiwara Osam Mazda Toshikazu Kubo 《International journal of molecular sciences》2015,16(1):1043-1050
Hypoxia-inducible factor (HIF)-2α is considered to play a major role in the progression of osteoarthritis. Recently, it was reported that pressure amplitude influences HIF-2α expression in murine endothelial cells. We examined whether hydrostatic pressure is involved in expression of HIF-2α in articular chondrocytes. Chondrocytes were cultured and stimulated by inflammation or hydrostatic pressure of 0, 5, 10, or 50 MPa. After stimulation, heat shock protein (HSP) 70, HIF-2α, nuclear factor kappa B (NF-κB), matrix metalloproteinase (MMP)-13, MMP-3, and vascular endothelial growth factor (VEGF) gene expression were evaluated. The levels of all gene expression were increased by inflammatory stress. When chondrocytes were exposed to a hydrostatic pressure of 5 MPa, HIF-2α, MMP-13, and MMP-3 gene expression increased significantly although those of HSP70 and NF-κB were not significantly different from the control group. In contrast, HIF-2α gene expression did not increase under a hydrostatic pressure of 50 MPa although HSP70 and NF-κB expression increased significantly compared to control. We considered that hydrostatic pressure of 5 MPa could regulate HIF-2α independent of NF-κB, because the level of HIF-2α gene expression increased significantly without upregulation of NF-κB expression at 5 MPa. Hydrostatic pressure may influence cartilage degeneration, inducing MMP-13 and MMP-3 expression through HIF-2α. 相似文献
4.
Suganuma K. Sakai T. Keun-Soo Kim Takagi Y. Sugimoto J. Ueshima M. 《Electronics Packaging Manufacturing, IEEE Transactions on》2002,25(4):257-261
Thermal stability of the circuit boards with a quad flat package (QFP) soldered with Sn-58wt%Bi-(0, 0.5 and 1.0) wt% Ag and their microstructural features were evaluated. The addition of 1.0 wt% Ag causes the formation of large primary Ag/sub 3/Sn precipitates in the solder while no primary Ag/sub 3/Sn is found in Sn-57Bi-0.5Ag. Thermo-Calc calculation indicates that the lowest limit content for the formation of primary Ag/sub 3/Sn is about 0.8 wt%. Heat-exposure below 100/spl deg/C has no serious degradation on the joint structure for all solders. Heat-exposure at 125/spl deg/C caused serious degradation in joint strength for all alloys. The contamination of Pb from Sn-Pb surface plating on the components reduces the interface tolerance by forming ternary Sn-Pb-Bi phase melting at low temperature. Thermal fatigue between -20 and 80/spl deg/C does not have any significant influence on joint structure. 相似文献
5.
Yoshiyuki Ueshima Shozo Mizoguchi Tooru Matsumiya Hiroyuki Kajioka 《Metallurgical and Materials Transactions B》1986,17(4):845-859
Solute distribution in dendrites during solidification of carbon steel was analyzed by unidirectional solidification experiments
and mathematical analysis. The characteristic of the mathematical analysis is that diffusion of solutes in solid and redistribution
of solutes at solid/liquid andδ/γ interfaces are taken into consideration. Based on the observed and calculated results, it was found that phosphorus was redistributed
fromγ-phase toδ-phase, and that manganese was slightly redistributed fromδ-phase toγ-phase. Therefore the concentrated region of phosphorus can be separated from that of manganese duringδ/γ transformation in the case of slow cooling. Moreover, it was concluded that rapid diffusion inδ-phase and the redistribution duringδ/γ transformation played an important role in the variation of the interdendritic concentrations of solutes with lower carbon
concentration. 相似文献
6.
To define the etiologic factors of Japanese cerebrovascular diseases, a pathological research was conducted on autopsy cases of stroke in Akita Prefecture. In most cases of cerebral hemorrhages, especially in the middle age group (30-59 of age), arteriosclerotic deviations in basal berebral arteries of the circle of Willis and intracerebral small arteries are not found. The authors conclude that cerebral hemorrhage may occur without relationship to disturbances of lipid metabolism, biochemically, and to atherosclerosis, pathologically. Concerning cerebral infarction, especially in the old generation (over 60 years of age), severe arteriosclerotic deviations were recognized both in basal cerebral and intracerebral arteries. These changes were highly influenced by the grade and duration of hypertension, and rarely influenced by hypercholesterolemia. According to the above-mentioned facts, the results obtained from out epidemiological survey were confirmed by the pathological studies. 相似文献
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Yoshiyuki Ueshima Yasushi Sawada Shozo Mizoguchi Hiroyuki Kajioka 《Metallurgical and Materials Transactions A》1989,20(8):1375-1383
The precipitation behavior of MnS after solidification was analyzed with low-carbon Fe−Si alloys. This system was chosen since
it has a wide temperature range for the δ/γ transformation. Experimental results showed that the amount of MnS precipitates
increased drastically between 1300°C and 1100°C, and MnS precipitates were segregated almost entirely in the δ phase. This
result was interpreted quantitatively by a mathematical model, taking into account the diffusion and the redistribution of
solute elements and also the solubility product limit of Mn and S in both phases. Mathematical analysis shows that the precipitation
of MnS starts first in the γ phase, but its growth will be very limited because of slow diffusion of Mn in the γ phase. The
effects of some factors such as cooling rate and Si content of alloys on the rate of precipitation were discussed, and the
degree of contributions of diffusion of Mn and the redistribution of S were estimated. 相似文献
10.
Teruyuki Ueshima Takeji Kokusho Toshiro Okamoto Hiroshi Yajima 《Nuclear Engineering and Design》1997,172(3):289
Predictive and correlative analyses of the forces vibration tests (‘FVT’ for short, hereafter:) and seismic response of the large-scale embedded structure were performed as one of the analytical phases of an international large-scale seismic test (LSST) program (Tang et al., 1991) at Hualien, Taiwan. Consequently, the following was clarified; (1) FVT analysis using unified ground model (UMFVT2) predicted the fundamental system frequency (ƒ0) about 20% higher than the test. (2) After careful investigation on several items cited as the presumed causes of (ƒ0) discrepancy between the test and the prediction, it was attributed to the Vs of the backfill, and best correlated ground model (BCFVT2) was formed, based on it. (3) Seismic response analysis using BCFVT2 brought a bit better agreement with the observation than using UMFVT2, but from another viewpoint, both analysis results agreed fairly well with the observation, indicating that backfill Vs does not affect seismic response so much as during FVT. 相似文献