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1.
Do individual factors matter? A survey of scientists’ patenting in Portuguese public research organisations 总被引:1,自引:0,他引:1
Paula Susana Figueiredo Moutinho Margarida Fontes Manuel Mira Godinho 《Scientometrics》2007,70(2):355-377
This paper addresses scientists’ behaviour regarding the patenting of knowledge produced in universities and other public
sector research organisations (PSROs). Recent years have witnessed a rapid growth in patenting and licensing activities by
PSROs. We argue that the whole process depends to a certain extent on scientists’ willingness to disclose their inventions.
Given this assumption, we conduct research into individual behaviour in order to understand scientists’ views concerning the
patenting of their research results. Data from a questionnaire survey of Portuguese researchers from nine PSROs in life sciences
and biotechnology is presented and analysed and complemented with in-depth interviews. The results reveal that overall the
scientists surveyed show a low propensity to become involved in patenting and licensing activities, despite the fact that
the majority had no “ethical” objections to the disclosure of their inventions and the commercial exploitation of these. Perceptions
about the impacts of these activities on certain fundamental aspects of knowledge production and dissemination are however
divergent. This may account for the low participation levels. Furthermore, most scientists perceived the personal benefits
deriving from this type of activity to be low. Similarly, the majority also believed that there are many difficulties associated
with the patenting process and that they receive limited support from their organisations, which lack the proper competences
and structures to assist with patenting and licensing. 相似文献
2.
3.
Towards a Reference Model for Surveying Mobile Agent Systems 总被引:2,自引:1,他引:1
4.
Server‐side component models such as Enterprise JavaBeans (EJB) add powerful abstractions to the bare ‘business objects’ layer in order to support a clean separation of server‐side application logic from other concerns such as distribution, security, transaction management and persistence. An improved separation of concerns is also the main goal of aspect‐oriented programming (AOP). This paper compares the two approaches and reasons about the possibility of substituting (parts of) component models using AOP mechanisms. We conclude that AOP is a promising approach to eliminate important shortcomings of the container‐based component approach. However, our analysis of concrete aspect‐oriented languages shows that current AOP technology is not yet mature enough to supersede component models. Copyright © 2003 John Wiley & Sons, Ltd. 相似文献
5.
A 71-year-old man was admitted due to brain infarction. An abnormal floating mass was found in the right atrium by echocardiography. The mass was assumed to be a thrombus. The patient was failed to be in danger of pulmonary embolism, so it was decided to remove surgically. The thrombus was removed under cardiopulmonary bypass including the atrial wall where it was attached, because it was difficult to rule out the possibility of cardiac tumor macroscopically. The tumor showed pathological findings of thrombus. Postoperative course was uneventful. 相似文献
6.
Hyun-Ah Shin Mira Park Jasvinder Paul Banga Helen Lew 《International journal of molecular sciences》2022,23(10)
Orbital fibroblasts (OFs) in thyroid-associated ophthalmopathy (TAO) are differentiated from pre-adipocytes and mature adipocytes; increased lipid and fat expansion are the major characteristics of ophthalmic manifestations. Human placental mesenchymal stem cells (hPMSCs) were reported to immunomodulate pathogenesis and suppress adipogenesis in TAO OFs. Here, we prepared transforming growth factor β (TGFβ, 20 ng/mL)-treated hPMSCs (TGFβ-hPMSCs) in order to enhance anti-adipogenic effects in vitro and in TAO mice. TAO OFs were grown in a differentiation medium and then co-cultured with hPMSCs or TGFβ-hPMSCs. TAO OFs were analyzed via quantitative real-time polymerase chain reaction, Oil red O staining, and western blotting. The results showed that TGFβ-hPMSCs reduced the expression of adipogenic, lipogenic, and fibrotic genes better than hPMSCs in TAO OFs. Moreover, the adipose area decreased more in TAO mice injected with TGFβ-hPMSCs compared to those injected with hPMSCs or a steroid. Further, TGFβ-hPMSCs inhibited inflammation as effectively as a steroid. In conclusion, TGFβ-hPMSCs suppressed adipogenesis and lipogenesis in vitro and in TAO mice, and the effects were mediated by the SMAD 2/3 pathways. Furthermore, TGFβ-hPMSCs exhibited anti-inflammatory and anti-fibrotic functions, which suggests that they could be a new and safe method to promote the anti-adipogenic function of hPMSCs to treat TAO patients. 相似文献
7.
A bottom-up method for creating a hierarchy of entity-relationship diagrams (HERD) from a given, flat ER diagram (ERD) is proposed. The hierarchy consists of simple and interrelated diagrams—ER structures—with external relationships to other structures. The HERD-tree diagram, which provides the most general view of the conceptual schema, is located at the top of the hierarchy. The method is based on packaging operations, which group entities and relationships according to certain criteria. These operations are applied in several steps on a given (presumably large-scale) ERD. We describe the new constructs, which are added to the ER model to enable the creation of HERD, and a bottom-up method for creating HERD. We also evaluate HERD from the point of view of user comprehension and preference, based on an experimental comparison to flat ERDs.
相似文献
Peretz ShovalEmail: |
8.
Ivar Jacobson Shihong Huang Mira Kajko-Mattsson Paul McMahon Ed Seymour 《Programming and Computer Software》2012,38(1):1-12
The purpose of writing this Three Year Vision paper is threefold. Firstly, it briefly recaps the progress Semat has made thus
far; secondly, it lays out the future directions for people working actively within the Semat community; thirdly, it provides
the background for seeking funding support from agencies, such as the European Community and the like. Funding support is
necessary to sustain the ongoing activities of Semat and its growth into a broader community effort, as most people working
within Semat are volunteers. As such, the paper may be both too much and too little for the wider supporter base. However,
we intend to make our work fully transparent, hence, we publish it widely. We seek feedback and comments from supporters and
signatories in order to improve the vision. In this context, other companion papers are being written to better address the
specific needs for the practitioners, the industry and the academia. 相似文献
9.
This article introduces a high-level system using belief functions for exchanging and managing imperfect information about events on the road in vehicular ad hoc networks. The main purpose of this application is to provide the most reliable information for the driver from multiple messages received informing the driver about events on the roads. This system and some variants are tested using a MATLAB? simulator. An implementation with Android smartphones using a Bluetooth technology to exchange the messages is also introduced. 相似文献
10.