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1.
A case of using the Semantic Interoperability Framework for custom orthopedic implants manufacturing
Milan Zdravković Miroslav Trajanović Miloš Stojković Dragan Mišić Nikola Vitković 《Annual Reviews in Control》2012,36(2):318-326
The efficiency and effectiveness of the daily practice in orthopedic surgery depend on the availability, interoperability and unique access to a wide set of information, related to the patient’s medical record and diagnosis, domain knowledge and available resources and staff. The most important of the tangible resources, needed for the therapeutic or preventive actions are orthopedic implants. In some cases, the implants may be highly complex and customized products, which need to be manufactured (assembled) on basis of the above information in a shortest possible timeframe. In this paper, the case of the custom orthopedic implants manufacturing is described from the perspective of the collaborative enterprising, with special consideration of the interoperability issues of the involved enterprise collaboration. It is shown how the previously developed Semantic Interoperability Framework can be used to improve the efficiency of the manufacturing and other relevant processes. 相似文献
2.
Emil Malchev Nikola Spassov Ghenov Nikolina Ivanova Ioncheva Stoyan Stoychev Tanchev Krassimira Kirilova Kalpakchieva 《Zeitschrift für Lebensmitteluntersuchung und -Forschung A》1989,189(3):229-231
Summary The higher fatty acids of dried red pepper of the variety of Gorogled were identified by gas chromatography with using help of authentic compounds. Their amounts were determined using on absolute calibration method.The following acids were established: lauric, myrastic, palmitic, palmitoleic, stearic, oleic, linoleic, linolenic,arachidic and behenic acids. The results obtained from the quantitative measurements showed that linoleic, linolenic and palmitic acids amounted to 80% of the total acids.The quantitative changes of identified acids in red pepper, of dried at 60°, 70°, 80° and 90 °C red pepper and stored as dried red pepper and red pepper powder over a 6-months period investigated.The results show that under the drying temperatures applied the amount of all fatty acids decreased with an increase in the temperature. During a storage a period of 3 months the amount of the respective acids decreased while the process was the most expressed in red pepper dried at a temperature of t = 70 °C.After a 6-months storage period under the drying condition applied the dried red pepper contained a greater amount of fatty acids compared with stored for 3 months.
Identifikation und Veränderungen der höheren Fettsäuren von gemahlenem Paprika und von getrockneten ungemahlenen Paprikaschoten
Zusammenfassung Es wurden gaschromatographisch mit Hilfe von Vergleichsubstanzen die höheren Fettsäuren, die im gemahlenen Paprika (Sorte Gorogled) enthalten sind, identifiziert. Die Mengen wurden nach der Methode der absoluten Kalibrierung bestimmt. Es wurden folgende Säuren festgestellt: Laurinsäure, Myristin-, Palmitin-, Palmitoolein-, Stearin-, Olein-, Linol-, Linolen-, Arachin- und Behensäure. Die quantitativen Ergebnisse zeigen, daß die Menge der Linolen-, Linol- und Palmitinsäure 80% der Gesamtsäurenmenge darstellt. Es wurden die quantitativen Veränderungen der Fettsäuren von Paprika (Sorte Gorogled) bei Temperaturen von 60 °, 70 °, 80 ° und 90 °C, getrocknet und als getrockneter ungemahlener bzw.gemahlener Paprika, gelagert und innerhalb von 6 Monaten in Abständen von 3 Monaten verfolgt. Bei den angewendeten Trocknungstemperaturen nimmt die Menge der einzelnen Fettsäuren in dem getrockneten ungemahlenen Paprika mit Erhöhung der Trocknungstemperatur ab. Die Lagerung des getrockneten ungemahlenen Paprikas innerhalb von 3 Monaten führt zur Abnahme der einzelnen Fettsäuren, wobei dieser Prozeß am stärksten bei einer Trocknungstemperatur von 70 °C verläuft. Nach einer 6monatigen Lagerung des getrockneten und ungemahlenen Paprikas, nach Trocknung und bei den o. g. vier Temperaturen, ist die Menge der Fettsäuren höher im Vergleich zu jener der Fettsäuren in getrocknetem ungemahlenem Paprika nach 3 Monaten. Nach 3 Monaten enthält der gemahlene Paprika weniger Fettsäuren als der getrocknete und ungemahlene Paprika.相似文献
3.
Definition of the problem
Full age patients with mental disorders and preserved decision-making capacity are increasingly interested in drafting advance directives. Whereas in Switzerland (as well as in Germany) advance directives are binding in principle, an advance directive is not binding and has only to be considered in case of involuntary admission due to a mental disorder. Thereby, the virtual aim of an advance directive – the anticipated self-determination – is questioned.Arguments
From an ethical perspective, patients with mental disorders have the same rights as patients with somatic diseases. Therefore, the question arises if there are good reasons for this unequal treatment. In the present contribution, four possible reasons are analyzed: (1) persons with mental disorders are “different”; (2) protection from self-harm; (3) often not present end-of-life context; (4) reduced bindingness as the more appropriate standard in general.Conclusion
The authors come to the conclusion that patients with mental disorders are often capable of composing a valid advance directive, and just as any other human being, they have a principal and binding right for self-determination, even though they are particularly vulnerable in crisis situations.4.
5.
为尽可能多地消除遥感图像变化检测过程中“伪变化”信息的影响,获得比较客观的感兴趣区域变化检测结果,针对遥感图像中SAR图像的特点,提出一种混合的SAR图像变化检测算法。对已配准好的图像进行Frost滤波,用邻域比值的方法构造差异图,对得到的差异图进行非下采样轮廓波变换(NSCT),对变换得到的高频子带和低频子带分别处理,用模糊C均值(FCM)聚类算法得到变化检测的结果。实验结果表明,该算法模型很好地保留了图像变化区域的细节,提高了变化检测准确性。 相似文献
6.
This Extended Technical Note shows that the final accuracy level of reverse engineered surfaces depends on scanning distance and scanning angle of the laser beam, hence it also depends on the morphology of the scanned objects. On scanning strongly curved objects, such as the ones with free form surfaces, the distance and impact angle of the laser beam are changing continuously during the scanning process. On the basis of these, two critical parameters are specified for the design model, which make it possible to predict these two factors in advance, depending on the morphology of the scanned object. First, a mathematical-statistical design model of the scanning process is generated, which relies on ANOVA (analysis of variance) and DOE (design of experiments). In the next step, a fitness function is optimized by the genetic algorithm (GA) program. This optimization improves the accuracy of the final scanned surfaces, in terms of the minimum standard deviation values of reverse engineered 3D surface model. The proposed approach was confirmed in a case study, which is presented at the end of this Technical Note. 相似文献
7.
Veronika Bilanovi
ov Nikola Rýdza Lilla Koczka Martin Hess Elena Feraru Jií Friml Tomasz Nodzyski 《International journal of molecular sciences》2022,23(11)
Much of plant development depends on cell-to-cell redistribution of the plant hormone auxin, which is facilitated by the plasma membrane (PM) localized PIN FORMED (PIN) proteins. Auxin export activity, developmental roles, subcellular trafficking, and polarity of PINs have been well studied, but their structure remains elusive besides a rough outline that they contain two groups of 5 alpha-helices connected by a large hydrophilic loop (HL). Here, we focus on the PIN1 HL as we could produce it in sufficient quantities for biochemical investigations to provide insights into its secondary structure. Circular dichroism (CD) studies revealed its nature as an intrinsically disordered protein (IDP), manifested by the increase of structure content upon thermal melting. Consistent with IDPs serving as interaction platforms, PIN1 loops homodimerize. PIN1 HL cytoplasmic overexpression in Arabidopsis disrupts early endocytic trafficking of PIN1 and PIN2 and causes defects in the cotyledon vasculature formation. In summary, we demonstrate that PIN1 HL has an intrinsically disordered nature, which must be considered to gain further structural insights. Some secondary structures may form transiently during pairing with known and yet-to-be-discovered interactors. 相似文献
8.
The idea of non-hierarchical production networks consisting of autonomous enterprises has been present in scientific community for more than 20 years. Although some global corporations are using their own production networks across continents, they are not similar to the original idea of non-hierarchical production networks in many aspects. It seems that this idea waited for production systems to acquire proper information and communications technology (ICT) or new industrial platforms, like Industry 4.0. The result is a new type of production network called Cyber-Physical Production Network (CPPN). The CPPN is, from ICT point of view, ready to act as non-hierarchical production networks consisting of autonomous production systems with many automated processes. One of the most important processes of the CPPN is a selection of optimal partners (enterprises) to be part of a new virtual enterprise, created inside production network. An optimisation problem emerges in this process, and it is called Partner Selection Problem (PSP). It is non-polynomial-hard combinatorial problem. Since metaheuristic algorithms are well-proven in solving that kind of problem, a specially designed metaheuristic algorithm derived from ant colony optimisation and named the HUMANT (HUManoid ANT) algorithm is used in this paper. It is multi-objective optimisation algorithm that successfully solves different instances of PSP with two, three, four or more objectives. 相似文献
9.
Silk electrogelation involves the transition of an aqueous silk fibroin solution to a gel state (E-gel) in the presence of an electric current. The process is based on local pH changes as a result of water electrolysis - generating H(+) and OH(-) ions at the (+) and (-) electrodes, respectively. Silk fibroin has a pI=4.2 and when local pH相似文献
10.
In this article, the role of the restoring stiffness, as one of the basic parameters in ship hydroelastic analysis, is brought
out. It is formulated using the variational principle and the method of virtual displacements. It is shown that asymmetry
of the restoring stiffness is a physical reality. Moreover, it is confirmed that modal variation, still disputed in the relevant
literature, has to be taken into account to satisfy the ship’s stability. Consistent stiffness is formulated here by regarding
stiffness definition as relation between forces and displacements. Hybrid stiffness known from the literature is wrong since
some terms are specified as relation between forces and displacement gradient. Influence of the consistent and symmetrized
stiffness matrix, and the hybrid one, on dynamic response is illustrated for a prismatic pontoon and a large container ship.
It is found that the latter two matrices do not assure convergence of transfer functions of sectional forces to zero value
as the wave frequency approaches zero. The rigid body and elastic responses are compared, and pertinent conclusions are drawn.
It is also shown that it is not necessary to use the unified geometric and restoring stiffness for ordinary hydroelastic analysis
of ship structures. The consistent formulation of the restoring stiffness matrix will be useful for extending linear potential
theory hydrodynamic codes for rigid body analysis to deformable bodies. 相似文献