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排序方式: 共有212条查询结果,搜索用时 15 毫秒
1.
Erika Aparecida Silveira Golnaz Vaseghi Annelisa Silva de Carvalho Santos Nathalie Kliemann Farzad Masoudkabir Matias Noll Noushin Mohammadifard Nizal Sarrafzadegan Cesar de Oliveira 《International journal of molecular sciences》2020,21(23)
The association between obesity, cancer and cardiovascular disease (CVD) has been demonstrated in animal and epidemiological studies. However, the specific role of visceral obesity on cancer and CVD remains unclear. Visceral adipose tissue (VAT) is a complex and metabolically active tissue, that can produce different adipokines and hormones, responsible for endocrine-metabolic comorbidities. This review explores the potential mechanisms related to VAT that may also be involved in cancer and CVD. In addition, we discuss the shared pharmacological treatments which may reduce the risk of both diseases. This review highlights that chronic inflammation, molecular aspects, metabolic syndrome, secretion of hormones and adiponectin associated to VAT may have synergistic effects and should be further studied in relation to cancer and CVD. Reductions in abdominal and visceral adiposity improve insulin sensitivity, lipid profile and cytokines, which consequently reduce the risk of CVD and some cancers. Several medications have shown to reduce visceral and/or subcutaneous fat. Further research is needed to investigate the pathophysiological mechanisms by which visceral obesity may cause both cancer and CVD. The role of visceral fat in cancer and CVD is an important area to advance. Public health policies to increase public awareness about VAT’s role and ways to manage or prevent it are needed. 相似文献
2.
Despite the universal and understandable distress associated with the death of a child from pediatric illness, do psychologists help surviving families in ways that match their need for assistance? Many families do not seek psychological help and cope adaptively with their loss. Indications for psychotherapy with bereaved families are based largely on experience with families who engage in treatment and who have greater distress. Other families may not receive sufficient services but are at risk for ongoing difficulties and unlikely to engage in treatment. Suggestions for intervention are made, with attention to the fit of therapeutic approaches with family needs. (PsycINFO Database Record (c) 2010 APA, all rights reserved) 相似文献
3.
Fiber-optic transmission of Q-switched ruby laser pulses is limited by fiber damage owing to the high laser-beam intensities. Pulse stretching with a semiconductor-based control circuit for the Pockels cell of the ruby laser to reduce the peak intensities is described. Pulses with durations from 200 ns to 1 μs and a coherence length of ~3 m were generated. These pulses were coupled into multimode optical fibers to investigate the transmission characteristics and the limits of transmittable pulse energies. Stretched pulses can be transmitted in quartz fibers with a 600-μm core diameter to pulse energies of 300 mJ, which is an increase by a factor of 4 compared with standard Q-switched pulses. It is expected that beam guiding of ruby laser pulses by fiber optics will significantly facilitate the use of holographic interferometry in technical applications such as vibration analysis. 相似文献
4.
5.
Homodyne detection in magnetic resonance imaging 总被引:8,自引:0,他引:8
Magnetic detection of complex images in magnetic resonance imaging (MRI) is immune to the effects of incidental phase variations, although in some applications information is lost or images are degraded. It is suggested that synchronous detection or demodulation can be used in MRI systems in place of magnitude detection to provide complete suppression of undesired quadrature components, to preserve polarity and phase information, and to eliminate the biases and reduction in signal-to-noise ratio (SNR) and contrast in low SNR images. The incidental phase variations in an image are removed through the use of a homodyne demodulation reference, which is derived from the image or the object itself. Synchronous homodyne detection has been applied to the detection of low SNR images, the reconstruction of partial k-space images, the simultaneous detection of water and lipid signals in quadrature, and the preservation of polarity in inversion-recovery images. 相似文献
6.
We develop nonsmooth optimization techniques to solve H/sub /spl infin// synthesis problems under additional structural constraints on the controller. Our approach avoids the use of Lyapunov variables and therefore leads to moderate size optimization programs even for very large systems. The proposed framework is versatile and can accommodate a number of challenging design problems including static, fixed-order, fixed-structure, decentralized control, design of PID controllers and simultaneous design and stabilization problems. Our algorithmic strategy uses generalized gradients and bundling techniques suited for the H/sub /spl infin// norm and other nonsmooth performance criteria. We compute descent directions by solving quadratic programs and generate steps via line search. Convergence to a critical point from an arbitrary starting point is proved and numerical tests are included to validate our methods. The proposed approach proves to be efficient even for systems with several hundreds of states. 相似文献
7.
In magnetic resonance imaging, magnetic field inhomogeneities cause distortions in images that are reconstructed by conventional fast Fourier trasform (FFT) methods. Several noniterative image reconstruction methods are used currently to compensate for field inhomogeneities, but these methods assume that the field map that characterizes the off-resonance frequencies is spatially smooth. Recently, iterative methods have been proposed that can circumvent this assumption and provide improved compensation for off-resonance effects. However, straightforward implementations of such iterative methods suffer from inconveniently long computation times. This paper describes a tool for accelerating iterative reconstruction of field-corrected MR images: a novel time-segmented approximation to the MR signal equation. We use a min-max formulation to derive the temporal interpolator. Speedups of around 60 were achieved by combining this temporal interpolator with a nonuniform fast Fourier transform with normalized root mean squared approximation errors of 0.07%. The proposed method provides fast, accurate, field-corrected image reconstruction even when the field map is not smooth. 相似文献
8.
LarsÅke Fredlund Dilian Gurov Thomas Noll Mads Dam Thomas Arts Gennady Chugunov 《International Journal on Software Tools for Technology Transfer (STTT)》2003,4(4):405-420
This paper presents an overview of the main results of the project Verification of ERLANG Programs , which is funded by the Swedish Business Development Agency (NUTEK) and by Ericsson within the ASTEC (Advanced Software TEChnology) initiative. Its main outcome is the ERLANG Verification Tool (EVT), a theorem prover which assists in obtaining proofs that ERLANG applications satisfy their correctness requirements formulated as behavioural properties in a modal logic with recursion. We give a summary of the verification framework as supported by EVT, discuss reasoning principles essential for successful proofs such as inductive and compositional reasoning, and an efficient treatment of side-effect-free code. The experiences of applying the tool in an industrial case study are summarised, and an approach for supporting verification in the presence of program libraries is outlined.EVT is essentially a classical proof assistant, or theorem-proving tool, requiring users to intervene in the proof process at crucial steps such as stating program invariants. However, the tool offers considerable support for automatic proof discovery through higher-level tactics tailored to the particular task of the verification of ERLANG programs. In addition, a graphical interface permits easy navigation through proof tableaux, proof reuse, and meaningful feedback about the current proof state, to assist users in taking informed proof decisions. 相似文献
9.
Marion Gabarrou Daniel Alazard Dominikus Noll 《Mathematics of Control, Signals, and Systems (MCSS)》2013,25(2):257-290
We design a feedback control architecture for longitudinal flight of an aircraft. The multi-level architecture includes the flight control loop to govern the short-term dynamics of the aircraft, and the autopilot to control the long-term modes. Using $H_\infty $ performance and robustness criteria, the problem is cast as a non-convex and non-smooth optimization program. We present a non-convex bundle method, prove its convergence, and show that it is apt to solve the longitudinal flight control problem. 相似文献
10.
Matthew V. Ball Cyril Guyot James P. Hughes Luther Martin Landon Curt Noll 《Cryptologia》2013,37(1):70-79
Abstract This paper describes the importance of the XTS-AES encryption mode of operation and concludes with a new proof for the security of ciphertext stealing as used by XTS-AES. The XTS-AES mode is designed for encrypting data stored on hard disks where there is not additional space for an integrity field. Given this lack of space for an integrity field, XTS-AES builds on the security of AES by protecting the storage device from many dictionary and copy/paste attacks. The operation of the XTS mode of AES is defined in the IEEE 1619-2007 standard [3], and has been adopted by the U.S. National Institute of Standards and Technology (NIST) as an approved mode of operation under FIPS 140-2 [2]. XTS-AES builds on the XEX (Xor-Encrypt-Xor) mode originally proposed by Rogaway [8]. 相似文献