Software assessment using metrics: A comparison across large C++ and Java systems

This paper presents an assessment method to evaluate the quality of object oriented software systems. The assessment method is based on source code abstraction, object–oriented metrics and graphical representation. The metrics used and the underlying model representing the software are presented. The assessment method experiment is part of an industrial research effort with the Bell Canada Quality Engineering and Research Group. It helps evaluators assess the quality and risks associated with software by identifying code fragments presenting unusual characteristics. The assessment method evaluates object–oriented software systems at three levels of granularity: system level, class level and method level. One large C++ and eight Java software systems, for a total of over one million lines of code, are presented as case studies. A critical analysis of the results is presented comparing the systems and the two languages.     

Genetic testing and psychology: New roles, new responsibilities.

Advances in genetics and genetic testing promise to catalyze a fundamental change in the practice of medicine. Psychologists have much to offer as psychotherapists, researchers, educators, and policymakers to a society heavily influenced by the genetic revolution. To make the most of new opportunities available to mental health professionals in genetics, psychologists must know basic genetic principles and learn what is new about 21st-century genetics. The core competencies for all health professionals developed by the National Coalition for Health Professional Education in Genetics are related in this article to the significant roles psychologists can play in helping individuals with genetic concerns to cope with vulnerability, optimize family interaction, and improve health behaviors. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Psychologists' contributions to the genetic revolution.

Responds to the comments of H. Goldsmith et al (see record 2003-05602-013) and S. Kéri (see record 2003-05602-014) regarding the article by A. Patenaude et al (see record 2002-12457-022) that discusses the role of psychologists in genetics and genetic testing. Patenaude reviews the comments made and states that both comments enlarge the discussion of the important roles psychologists will continue to play as genetics advances the knowledge of the etiology and treatment of disorders. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Quantifying forest above ground carbon content using LiDAR remote sensing

The UNFCCC and interest in the source of the missing terrestrial carbon sink are prompting research and development into methods for carbon accounting in forest ecosystems. Here we present a canopy height quantile-based approach for quantifying above ground carbon content (AGCC) in a temperate deciduous woodland, by means of a discrete-return, small-footprint airborne LiDAR. Fieldwork was conducted in Monks Wood National Nature Reserve UK to estimate the AGCC of five stands from forest mensuration and allometric relations. In parallel, a digital canopy height model (DCHM) and a digital terrain model (DTM) were derived from elevation measurements obtained by means of an Optech Airborne Laser Terrain Mapper 1210. A quantile-based approach was adopted to select a representative statistic of height distributions per plot. A forestry yield model was selected as a basis to estimate stemwood volume per plot from these heights metrics. Agreement of r=0.74 at the plot level was achieved between ground-based AGCC estimates and those derived from the DCHM. Using a 20×20 m grids superposed to the DCHM, the AGCC was estimated at the stand level and at the woodland level. At the stand level, the agreement between the plot data upscaled in proportion to area and the LiDAR estimates was r=0.85. At the woodland level, LiDAR estimates were nearly 24% lower than those from the upscaled plot data. This suggests that field-based approaches alone may not be adequate for carbon accounting in heterogeneous forests. Conversely, the LiDAR 20×20 m grid approach has an enhanced capability of monitoring the natural variability of AGCC across the woodland.     

Attitudes of 47 mothers of pediatric oncology patients toward genetic testing for cancer predisposition

PURPOSE: To assess attitudes toward testing for cancer susceptibility genes, we interviewed mothers of pediatric oncology patients about their cancer causation theories, interest in hypothetical predisposition testing for themselves and their healthy children, and anticipated impact of testing. PATIENTS AND METHODS: The subjects were 47 mothers of two or more living children, one of whom was 6 to 24 months postdiagnosis of cancer. Potential risks and benefits of hypothetical genetic predisposition testing for cancer susceptibility were described. A semistructured interview assessed the following: (1) recall of discussions with the pediatric oncologist about the possible role of heredity in causing the child's cancer; (2) mothers' personal theories of the etiology of their child's cancer; (3) family cancer history; (4) interest in genetic predisposition testing for themselves and unaffected (cancer-free) children; and (5) expected sequelae of testing. RESULTS: If genetic cancer predisposition tests were available, 51% of mothers would test themselves and 42% would test healthy children, even with no medical benefit. With established medical benefit, an additional 36% of mothers would seek testing for themselves and another 49% would test their healthy children. Interest in cancer predisposition testing among mothers extended far beyond those with significant family histories of cancer. Most mothers would consider minor children's wishes in the decision about testing and would tell children under age 18 their test results. CONCLUSION: As increasing numbers of cancer susceptibility genes are identified, parents of pediatric oncology patients may be receptive to opportunities to test themselves and their healthy children. Counseling will be important to aid in decisions about testing. Research is essential to evaluate the long-term impact of predisposition testing.     

Noncoherent diversity reception over Nakagami-fading channels

A method for computing the average bit-error probability of binary differential phase-shift keying (DPSK) and frequency shift-keying (FSK) signals transmitted over Nakagami asymptotically slow fading channels with postdetection diversity reception is presented to extend previously published results. The previously published results apply only for maximum ratio combining, i.e., with predetection combining, where phase coherency is necessary. The results for postdetection combining are derived with the explicit expressions for the most practical cases of independent channels and particular cases of correlated channels     

The value of pancuronium in prolonged intraocular operations

We wished to determine the effectiveness of Pancuronium, a non-depolarizing muscle relaxant, in prolonged intraocular operations. We compared the variations in intraocular pressure when using four different methods of induction of general anesthesia. With Pancuronium the intraocular pressure fell initially and then rose to just below pre-induction levels and remained there. Our study suggests that pancuronium stabilizes intraocular pressure at a level which is highly desirable for intraocular surgery.     

The effect of the descent technique and truck cabin layout on the landing impact forces

The majority of injuries to truckers are caused by falls during the descent from the cab of the truck. Several studies have shown that the techniques used to descend from the truck and the layout of the truck's cabin are the principal cause of injury. The goal of the present study was to measure the effects of the descent techniques used by the trucker and the layout of the truck's cabin on the impact forces absorbed by the lower limbs and the back. Kinematic data, obtained with the aid of a video camera, were combined with the force platform data to allow for calculation of the lower limb and L₅–S₁ torques as well as L₅–S₁ compressive forces. The trucker descended from two different conventional tractor cabin layouts. Each trucker descended from cabin using either “facing the truck” (FT) or “back to the truck” (BT) techniques. The results demonstrate that the BT technique produces greater ground impact forces than the FT technique, particularly when the truck does not have a handrail. The BT technique also causes an increase in the compressive forces exerted on the back. In conclusion, the use of the FT technique along with the aids (i.e., handrails and all the steps) help lower the landing impact forces as well as the lumbosacral compressive forces.     

Non-invasive diagnosis of venous thromboembolism in outpatients

BACKGROUND: We designed a simple and integrated diagnostic algorithm for acute venous thromboembolism based on clinical probability assessment of deep-vein thrombosis (DVT) or pulmonary embolism (PE), plasma D-dimer measurement, lower-limb venous compression ultrasonography, and lung scan to reduce the need for phlebography and pulmonary angiography. METHODS: 918 consecutive patients presenting at the emergency ward of the Geneva University Hospital, Geneva, Switzerland, and H?pital Saint-Luc, Montreal, Canada, with clinically suspected venous thromboembolism were entered into a sequential diagnostic protocol. Patients in whom venous thromboembolism was deemed absent were not given anticoagulants and were followed up for 3 months. FINDINGS: A normal D-dimer concentration (<500 microg/L by a rapid ELISA) ruled out venous thromboembolism in 286 (31%) members of the study cohort, whereas DVT by ultrasonography established the diagnosis in 157 (17%). Lung scan was diagnostic in 80 (9%) of the remaining patients. Venous thromboembolism was also deemed absent in patients with low to intermediate clinical probability of DVT and a normal venous ultrasonography (236 [26%] patients), and in patients with a low clinical probability of PE and a non-diagnostic result on lung scan (107 [12%] patients). Pulmonary angiography and phlebography were done in only 50 (5%) and 2 (<1%) of the patients, respectively. Hence, a non-invasive diagnosis was possible in 866 (94%) members of the entire cohort. The 3-month thromboembolic risk in patients not given anticoagulants, based on the results of the diagnostic protocol, was 1.8% (95% CI 0.9-3.1). INTERPRETATION: A diagnostic strategy combining clinical assessment, D-dimer, ultrasonography, and lung scan gave a non-invasive diagnosis in the vast majority of outpatients with suspected venous thromboembolism, and appeared to be safe.     

Liver transplantation: review of the literature. Part 3: Medical complications

The first attempted human orthotopic liver transplantation, in 1963, involved a child with biliary atresia, who died on the operating table as a result of uncontrollable coagulopathy. Improvements in immunosuppression, surgical technique, medical imaging and postoperative care, as well as more stringent patient selection, have allowed the development of liver transplantation and its universal acceptance as the treatment for a variety of liver diseases. The radiologist plays a major role in the multidisciplinary transplantation team and must be familiar with each stage of orthotopic liver transplantation and its associated complications. In the first article of this series (Can Assoc Radiol J 1997;48[3]: 171-178), the authors reviewed the anatomic features and current concepts relevant to orthotopic liver transplantation. In the second article (Can Assoc Radiol J 1997;48[4]: 231-242), they discussed the vascular and biliary complications of the operation. This, the third and final article in the series, covers the medical complications.