Properties of poly(ethylene terephthalate)–poly(ethylene naphthalene 2,6‐dicarboxylate) blends with montmorillonite clay

The production and properties of blends of poly(ethylene terephthalate) (PET) and poly(ethylene naphthalene 2,6‐dicarboxylate) (PEN) with three modified clays are reported. Octadecylammonium chloride and maleic anhydride (MAH) are used to modify the surface of the montmorillonite–Na⁺ clay particles (clay–Na⁺) to produce clay–C18 and clay–MAH, respectively, before they are mixed with the PET/PEN system. The transesterification degree, hydrophobicity and the effect of the clays on the mechanical, rheological and thermal properties are analysed. The PET–PEN/clay–C18 system does not show any improvements in the mechanical properties, which is attributed to poor exfoliation. On the other hand, in the PET–PEN/clay–MAH blends, the modified clay restricts crystallization of the matrix, as evidenced in the low value of the crystallization enthalpy. The process‐induced PET–PEN transesterification reaction is affected by the clay particles. Clay–C18 induces the largest proportion of naphthalate–ethylene–terephthalate (NET) blocks, as opposed to clay–Na⁺ which renders the lowest proportion. The clay readily incorporates in the bulk polymer, but receding contact‐angle measurements reveal a small influence of the particles on the surface properties of the sample. The clay–Na⁺ blend shows a predominant solid‐like behaviour, as evidenced by the magnitude of the storage modulus in the low‐frequency range, which reflects a high entanglement density and a substantial degree of polymer–particle interactions. Copyright © 2005 Society of Chemical Industry     

The importance of information localization in scene gist recognition.

People can recognize the meaning or gist of a scene from a single glance, and a few recent studies have begun to examine the sorts of information that contribute to scene gist recognition. The authors of the present study used visual masking coupled with image manipulations (randomizing phase while maintaining the Fourier amplitude spectrum; random image structure evolution [RISE]; J. Sadr & P. Sinha, 2004) to explore whether and when unlocalized Fourier amplitude information contributes to gist perception. In 4 experiments, the authors found that differences between scene categories in the Fourier amplitude spectrum are insufficient for gist recognition or gist masking. Whereas the global 1/f spatial frequency amplitude spectra of scenes plays a role in gist masking, local phase information is necessary for gist recognition and for the strongest gist masking. Moreover, the ability to recognize the gist of a target image was influenced by mask recognizability, suggesting that conceptual masking occurs even at the earliest stages of scene processing. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Finding trajectories of feature points in a monocular image sequence

Identifying the same physical point in more than one image, the correspondence problem, is vital in motion analysis. Most research for establishing correspondence uses only two frames of a sequence to solve this problem. By using a sequence of frames, it is possible to exploit the fact that due to inertia the motion of an object cannot change instantaneously. By using smoothness of motion, it is possible to solve the correspondence problem for arbitrary motion of several nonrigid objects in a scene. We formulate the correspondence problem as an optimization problem and propose an iterative algorithm to find trajectories of points in a monocular image sequence. A modified form of this algorithm is useful in case of occlusion also. We demonstrate the efficacy of this approach considering synthetic, laboratory, and real scenes.     

Plumbagin,a Biomolecule with (Anti)Osteoclastic Properties

Plumbagin is a plant-derived naphthoquinone that is widely used in traditional Asian medicine due to its anti-inflammatory and anti-microbial properties. Additionally, plumbagin is cytotoxic for cancer cells due to its ability to trigger reactive oxygen species (ROS) formation and subsequent apoptosis. Since it was reported that plumbagin may inhibit the differentiation of bone resorbing osteoclasts in cancer-related models, we wanted to elucidate whether plumbagin interferes with cytokine-induced osteoclastogenesis. Using C57BL/6 mice, we unexpectedly found that plumbagin treatment enhanced osteoclast formation and that this effect was most pronounced when cells were pre-treated for 24 h with plumbagin before subsequent M-CSF/RANKL stimulation. Plumbagin caused a fast induction of NFATc1 signalling and mTOR-dependent activation of p70S6 kinase which resulted in the initiation of protein translation. In line with this finding, we observed an increase in RANK surface expression after Plumbagin stimulation that enhanced the responsiveness for subsequent RANKL treatment. However, in Balb/c mice and Balb/c-derived RAW264.7 macrophages, these findings could not be corroborated and osteoclastogenesis was inhibited. Our results suggest that the effects of plumbagin depend on the model system used and can therefore either trigger or inhibit osteoclast formation.     

Myopic vs. far-sighted behaviours in a revenue-sharing supply chain with reference quality effects

In this paper, we consider a dynamic supply chain where a manufacturer produces and distributes a featured product through an exclusive retailer to end consumers. The manufacturer decides the product quality and wholesale price, while the retailer sets the retail price in the presence of a revenue-sharing contract and consumers’ reference quality effects. The objective of this study is to investigate the impacts of myopic behaviour regarding the reference quality on the product quality and pricing strategies and profits of both members. Our results suggest that the manufacturer’s myopia leads to a higher quality, higher price strategy and a higher quality–price ratio which benefits consumers. Meanwhile, relative to the far-sighted behaviour, myopia results in a more quality-sensitive but less price-sensitive market demand. What’s more, we find that the manufacturer is apt to act in a far-sighted way, but the retailer isn’t always willing to cooperate with a far-sighted manufacturer. Taking myopic strategies for both members is likely to gain a high profit of the whole supply chain for a relatively high marginal contribution of product quality on demand and a relatively low revenue-sharing proportion.     

A note on productivity gains in flexible robotic cells

Flexible robotic cells combine the capabilities of robotic flow shops with those of flexible manufacturing systems. In an m-machine flexible cell, each part visits each machine in the same order. However, the m operations can be performed in any order, and each machine can be configured to perform any operation. We derive the maximum percentage increase in throughput that can be achieved by changing the assignment of operations to machines and then keeping that assignment constant throughout a lot's processing. We find that no increase can be gained in two-machine cells, and that the gain in three- and four-machine cells each is at most 14 %.     

Interoperability issues in heterogeneous network management

The presence of dissimilar network models and standards necessitates interoperability as a means of achieving ubiquitous connectivity and management. The primary focus of this paper is to identify interoperability issues, independent of the network management model, which form the basis for developing interworking paradigms. Network Management and Interoperability related concepts and terminology are introduced and a generic network management framework is presented. Based on the generic framework, interoperability issues for developing paradigms are identified systematically. Different paradigms for interoperability are described and compared. The techniques used by these paradigms in addressing the issues identified are discussed.     

A combined theoretical and experimental investigation of the valorization of mechanical and thermal properties of the fly ash-reinforced polypropylene hybrid composites

Journal of Materials Science - Fly ash (FA) particles were surface modified with cetyltrimethylammonium bromide (Ctab) and hybridized with graphene oxide (GO) and carboxymethyl cellulose (CMC)...     

Identification of Natural Products as Potential Pharmacological Chaperones for Protein Misfolding Diseases

Defective protein folding and accumulation of misfolded proteins is associated with neurodegenerative, cardiovascular, secretory, and metabolic disorders. Efforts are being made to identify small-molecule modulators or structural-correctors for conformationally destabilized proteins implicated in various protein aggregation diseases. Using a metastable-reporter-based primary screen, we evaluated pharmacological chaperone activity of a diverse class of natural products. We found that a flavonoid glycoside ( C-10 , chrysoeriol-7-O-β-D-glucopyranoside) stabilizes metastable proteins, prevents its aggregation, and remodels the oligomers into protease-sensitive species. Data was corroborated with additional secondary screen with disease-specific pathogenic protein. In vitro and cell-based experiments showed that C-10 inhibits α-synuclein aggregation which is implicated in synucleinopathies-related neurodegeneration. C-10 interferes in its structural transition into β-sheeted fibrils and mitigates α-synuclein aggregation-associated cytotoxic effects. Computational modeling suggests that C-10 binds to unique sites in α-synuclein which may interfere in its aggregation amplification. These findings open an avenue for comprehensive SAR development for flavonoid glycosides as pharmacological chaperones for metastable and aggregation-prone proteins implicated in protein conformational diseases.