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Innovations in Systems and Software Engineering - One of the most important modules of computer systems is the one that is responsible for user safety. It was proven that simple passwords and...  相似文献   
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The reactivity of BaZrO3 with CO2 has been addressed as one of the major challenges with BaZrO3‐based electrolytes in protonic ceramic fuel cells. Here, we present a study of the effect of CO2 exposure on BaZrO3‐materials at elevated temperatures. Dense BaZr1?xYxO3?x/2 (x = 0, 0.05, 0.1, 0.2) and BaCe0.2Zr0.7Y0.1O2.95 ceramics were prepared by sintering of powder prepared by spray pyrolysis. The Vickers indentation method was used to determine the hardness and estimate the fracture toughness of pristine materials as well as the corresponding materials exposed to CO2. Formation of BaCO3 on the surface of exposed ceramics was confirmed by X‐ray diffraction and electron microcopy. The reaction resulted in formation of Ba‐deficient perovskite at the exposed surface. The reaction with CO2 was most pronounced at 650°C compared to the other temperatures applied in the study. The reactivity was also shown to depend on the Y‐content and the grain size and was most pronounced for BaZr0.9Y0.1O2.95. The reaction with CO2 was observed to have a profound effect on the fracture toughness of the ceramics, demonstrating a depression of the mechanical stability of the materials. The results are discussed with respect to the chemical and mechanical stability of BaZrO3 materials, with particular emphasis on the composition and grain size.  相似文献   
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Regulatory changes occurring early in colorectal cancer development remain poorly investigated. Since the majority of cases develop from polyps in the adenoma-carcinoma transition, a search of early molecular features, such as aberrations in miRNA expression occurring prior to cancer development, would enable identification of potentially causal, rather than consequential, candidates in the progression of polyp to cancer. In the current study, by employing small RNA-seq profiling of colon biopsy samples, we described differentially expressed miRNAs and their isoforms in the adenoma-carcinoma transition. Analysis of healthy-adenoma-carcinoma sequence in an independent validation group enabled us to identify early deregulated miRNAs including hsa-miR-1246 and hsa-miR-215-5p, the expressions of which are, respectively, gradually increasing and decreasing. Loss-of-function experiments revealed that inhibition of hsa-miR-1246 lead to reduced cell viability, colony formation, and migration rate, thereby indicating an oncogenic effect of this miRNA in vitro. Subsequent western blot and luciferase reporter assay provided evidence of hsa-miR-1246 being involved in the regulation of target AXIN2 and CFTR genes’ expression. To conclude, the present study revealed possible involvement of hsa-miR-1246 in early colorectal cancer development and regulation of tumor suppressors AXIN2 and CFTR.  相似文献   
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The paper presents a 3D‐based adaptive first‐order shell finite element to be applied to hierarchical modelling and adaptive analysis of complex structures. The main feature of the element is that it is equipped with 3D degrees of freedom, while its mechanical model corresponds to classical first‐order shell theory. Other useful features of the element are its modelling and adaptive capabilities. The element is assigned to hierarchical modelling and hpq‐adaptive analysis of shell parts of complex structures consisting of solid, thick‐ and thin‐shell parts, as well as of transition zones, where h, p and q denote the mesh density parameter and the longitudinal and transverse orders of approximation, respectively. The proposed hp‐adaptive first‐order shell element can be joined with 3D‐based hpq‐adaptive hierarchical shell elements or 3D hpp‐adaptive solid elements by means of the family of 3D‐based hpq/hp‐ or hpp/hp‐adaptive transition elements. The main objective of the first part of our research, presented in this paper, is to provide non‐standard information on the original parts of the element algorithm. In order to do that, we present the definition of shape functions necessary for p‐adaptivity, as well as the procedure for imposing constraints corresponding to the lack of elongation of the straight lines perpendicular to the shell mid‐surface, which is the procedure necessary for q‐adaptivity. The 3D version of constrained approximation presented next is the basis for h‐adaptivity of the element. The second part of our research, devoted to methodology and results of the numerical research on application of the element to various plate and shell problems, are described in the second part of this paper. Copyright © 2006 John Wiley & Sons, Ltd.  相似文献   
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This exploratory study is to analyze the communication differences among viewers of US TV program Friends on Internet discussion forum in the US, Japan, and Taiwan. It intends to establish whether exposure to foreign TV could lead to similar communication content in the context of the virtual community between exporting and importing societies. Content analysis was used in this cross-cultural study, with the aim of understanding the ways in which dialogues posted on various discussion forums differed among the United States, Japan, and Taiwan. The results of this exploratory study support the notion that the process of cultural value influence is more complex than cultural imperialism advocates propose. Audiences respond actively rather than passively to foreign TV programs. Prior information structure of the audience is affecting the interpretation of subsequent information.  相似文献   
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Recent years have witnessed considerable progress in the development of solar cells based on lead halide perovskite materials. However, their intrinsic instability remains a limitation. In this context, the interplay between the thermal degradation and the hydrophobicity of perovskite materials is investigated. To this end, the salt 1‐(4‐ethenylbenzyl)‐3‐(3,3,4,4,5,5,6,6,7,7,8,8,8‐tridecafluorooctylimidazolium iodide (ETI), is employed as an additive in hybrid perovskites, endowing the photoactive materials with high thermal stability and hydrophobicity. The ETI additive inhibits methylammonium (MA) permeation in methylammonium lead triiodide (MAPbI3) occurring due to intrinsic thermal degradation, by inhibiting out‐diffusion of the MA+ cation, preserving the pristine material and preventing decomposition. With this simple approach, high efficiency solar cells based on the unstable MAPbI3 perovskite are markedly stabilized under maximum power point tracking, leading to greater than twice the preserved efficiency after 700 h of continuous light illumination and heating (60 °C). These results suggest a strategy to tackle the intrinsic thermal decomposition of MAI, an essential component in all state‐of‐the‐art perovskite compositions.  相似文献   
9.
The photovoltaic(PV)market is currently dominated by silicon based solar cells.However technological diversification is essential to promote competition,which is the driving force for technological growth.Historically,the choice of PV materials has been limited to the three-dimensional(3D)compounds with a high crystal symmetry and direct band gap.However,to meet the strict demands for sustainable PV applications,material space has been expanded beyond 3D compounds.In this perspective we discuss the potential of low-dimensional materials(2D,1D)for application in PVs.We present unique features of low-dimensional materials in context of their suitability in the solar cells.The band gap,absorption,carrier dynamics,mobility,defects,surface states and growth kinetics are discussed and compared to 3D counterparts,providing a comprehensive view of prospects of low-dimensional materials.Structural dimensionality leads to a highly anisotropic carrier transport,complex defect chemistry and peculiar growth dynamics.By providing fundamental insights into these challenges we aim to deepen the understanding of low-dimensional materials and expand the scope of their application.Finally,we discuss the current research status and development trend of solar cell devices made of low-dimensional materials.  相似文献   
10.
Steam reforming is one method of producing hydrogen. The endothermic decomposition process of mixtures consisting of methane and water vapour under pressures of up to 4.0 MPa is conducted at a temperature of up to 780°C in austenite pipes cast centrifugally and filled with nickel catalytic agent. The results of microstructure tests on the welded joints of centrifugally cast catalytic pipes, made of second generation alloy IN 519 and third generation alloy H39WM, are presented in this article. The tests were conducted on butt welds drawn from the area of the substrate inlet of an approx. 500°C temperature, and from the area of maximum speed of pipe creep. The temperature of the pipe's external wall at the outlet of the products approaches 900°C under the operating conditions of ammonia reformers when internal pressure reaches up to 4.0 MPa. Long-lasting operational results in phase and structural changes depend on the local temperature of the pipe material. These changes affect the mechanical properties of the pipe material and contribute to initiation of the creep process, which manifests itself in macroscopic aspect as a local increase in the diameter of the pipes. The extreme stage of the high-temperature degradation of the microstructure reveals itself as macro-cracks leading to a loss of pipe leak-tightness.  相似文献   
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