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排序方式: 共有69条查询结果,搜索用时 15 毫秒
1.
Kargl F. Papadimitratos P. Buttyan L. Müter M. Schoch E. Wiedersheim B. Ta-Vinh Thong Calandriello G. Held A. Kung A. Hubaux J.-P. 《Communications Magazine, IEEE》2008,46(11):110-118
Vehicular communication systems are on the verge of practical deployment. Nonetheless, their security and privacy protection is one of the problems that have been addressed only recently. In order to show the feasibility of secure VC, certain implementations are required. In [1] we discuss the design of a VC security system that has emerged as a result of the European SeVe- Com project. In this second article we discuss various issues related to the implementation and deployment aspects of secure VC systems. Moreover, we provide an outlook on open security research issues that will arise as VC systems develop from today?s simple prototypes to fullfledged systems. 相似文献
2.
JF Seymour CG Begley U Dirksen JJ Presneill NA Nicola PE Moore OD Schoch P van Asperen B Roth S Burdach AR Dunn 《Canadian Metallurgical Quarterly》1998,92(8):2657-2667
The pathogenesis of acquired pulmonary alveolar proteinosis (PAP), a rare lung disease characterized by excessive surfactant accumulation within the alveolar space, remains obscure. Gene-targeted mice lacking the hematopoietic growth factor granulocyte-macrophage colony-stimulating factor (GM-CSF) or the signal-transducing beta-common chain of the GM-CSF receptor have impaired surfactant clearance and pulmonary pathology resembling human PAP. We therefore investigated the hematopoietic effects of GM-CSF in patients with PAP. The hematologic response of 5 infants with congenital PAP to 5 microgram/kg/d was of normal magnitude. By contrast, despite normal expression of GM-CSF receptor alpha- and beta-common chains on peripheral blood myelomonocytic cells (n = 6) and normal binding affinity of bone marrow mononuclear cells for GM-CSF (n = 3), each of the 12 patients with acquired PAP treated displayed impaired responses to GM-CSF; 5 microgram/kg/d produced only minor eosinophilia, and doses of 7.5 to 20 microgram/kg were required to induce >/=1.5-fold neutrophil increments in the 3 patients who underwent dose-escalation. However, neutrophilic responses to 5 microgram/kg granulocyte colony-stimulating factor (G-CSF) were normal (n = 4). In vitro, the proportion of hematopoietic progenitors responsive to GM-CSF (16.1% +/- 8.9%; P = .042) or interleukin-3 (IL-3; 19.3% +/- 7.7%; P = .063), both of which utilize the beta-common chain of the GM-CSF receptor complex, were reduced among patients with acquired PAP (n = 4) compared with normal bone marrow donor controls (47.2% +/- 25.9% and 40.9% +/- 18.6%, respectively). In the one individual who had complete resolution of lung disease during the period of study, this was temporally associated with correction of this defective in vitro response to GM-CSF and IL-3 on serial assessment. These data establish that patients with acquired PAP have an associated impaired responsiveness to GM-CSF that is potentially pathogenic in the development of their lung disease. Based on these observations, we propose a model of the pathogenesis of acquired PAP that suggests the disease arises as a consequence of an acquired clonal disorder within the hematopoietic progenitor cell compartment. 相似文献
3.
Ulrich Schoch Jürg Lüthy und Christian Schlatter 《Zeitschrift für Lebensmitteluntersuchung und -Forschung A》1984,178(5):351-355
Zusammenfassung In Rohextrakten von 18Penicillium camemberti- und 6P. roqueforti-Stämmen, die als Reifungsorganismen bei der Schimmelkäseproduktion in Schweizer Käsereien eingesetzt werden, wurde das mutagene Potential mit Hilfe des Ames-Testes bestimmt. In keinem der geprüften Extrakte konnte eine mutagene Aktivität festgestellt werden. Roquefortin, ein in Blauschimmelkäsen nachweisbares Mykotoxin vonP. roqueforti, erwies sich im Ames-Test als nicht mutagen. Die ermittelten Resultate ergaben keine Anhaltspunkte für genotoxische Effekte durch die Konsumation von schimmelgereiftem Käse.
Auszug aus der Dissertation von U. Schoch, Mykotoxine in schimmelgereiften Käsen, Diss. ETH Nr. 7278, ETH Zürich, 1983 相似文献
Mutagenicity testing of commercialP. Camemberti- andP. roqueforti-strains
Summary We tested the mutagenic potential of crude extracts of 18 strains ofPenicillium camemberti- and 6 strains ofP. roqueforti, which are used commercially in the production of mould ripened cheese in Switzerland. No mutagenic activity could be detected in any of the extracts. Roquefortine, a mycotoxin ofP. roqueforti, often found in Blue cheese, was negative in the Amestest. The results obtained do not lead reasons for experting undesired long term effects from the consumption of mould ripened cheese.
Auszug aus der Dissertation von U. Schoch, Mykotoxine in schimmelgereiften Käsen, Diss. ETH Nr. 7278, ETH Zürich, 1983 相似文献
4.
OD Schoch 《Canadian Metallurgical Quarterly》1997,127(29-30):1223-1228
In Africa, a rapid increase of human immunodeficiency virus (HIV)-associated tuberculosis cases has been observed; 80% of a worldwide 6 million dually infected persons live in this part of the world. The annual risk of progression to clinically overt tuberculosis in dually infected persons approaches the lifetime risk in persons with tuberculosis but no HIV infection. Zimbabwe is an example which illustrates the rapid increase in notified tuberculosis cases since 1985, accounted for primarily by HIV-associated tuberculosis cases. In sputum-smear positive HIV-associated tuberculosis, classical symptoms are reported with the same frequency as in HIV negative cases. Thus, case-finding activities need not be altered. In sputum-smear negative patients, reliable diagnostic tests are not available. Therapeutic trials are widely used and this causes overdiagnosis of tuberculosis. Extrapulmonary manifestations are common in HIV-associated tuberculosis. A majority of lymph node enlargements, pleurisy and pericarditis in Africa are now due to tuberculosis. If compliance is ensured, response to chemotherapy is excellent, but overall case fatality and relapse rates are increased. The cost-effectiveness of tuberculosis control programmes using directly observed therapy for at least the first 2 months of treatment is well established. With the prominent global significance of tuberculosis and the possibility of cost-effective interventions, a commitment to the fight against the worldwide epidemic is more important than ever before. 相似文献
5.
6.
Mike Spillane Ryan Schoch Matt Cooke Travis Harvey Mike Greenwood Richard Kreider Darryn S Willoughby 《Journal of the International Society of Sports Nutrition》2009,6(1):6-14
Numerous creatine formulations have been developed primarily to maximize creatine absorption. Creatine ethyl ester is alleged
to increase creatine bio-availability. This study examined how a seven-week supplementation regimen combined with resistance
training affected body composition, muscle mass, muscle strength and power, serum and muscle creatine levels, and serum creatinine
levels in 30 non-resistance-trained males. In a double-blind manner, participants were randomly assigned to a maltodextrose
placebo (PLA), creatine monohydrate (CRT), or creatine ethyl ester (CEE) group. The supplements were orally ingested at a
dose of 0.30 g/kg fat-free body mass (approximately 20 g/day) for five days followed by ingestion at 0.075 g/kg fat free mass
(approximately 5 g/day) for 42 days. Results showed significantly higher serum creatine concentrations in PLA (p = 0.007)
and CRT (p = 0.005) compared to CEE. Serum creatinine was greater in CEE compared to the PLA (p = 0.001) and CRT (p = 0.001)
and increased at days 6, 27, and 48. Total muscle creatine content was significantly higher in CRT (p = 0.026) and CEE (p
= 0.041) compared to PLA, with no differences between CRT and CEE. Significant changes over time were observed for body composition,
body water, muscle strength and power variables, but no significant differences were observed between groups. In conclusion,
when compared to creatine monohydrate, creatine ethyl ester was not as effective at increasing serum and muscle creatine levels
or in improving body composition, muscle mass, strength, and power. Therefore, the improvements in these variables can most
likely be attributed to the training protocol itself, rather than the supplementation regimen. 相似文献
7.
An elective laboratory course has been developed at Rensselaer Polytechnic Institute to motivate freshmen for further study of engineering in general and to spur interest in electrical and computer engineering in particular. The course philosophy is that hands-on laboratory and design experiences build student confidence, stimulate curiosity, and demonstrate the relevance of engineering work — thereby increasing motivation and retention. This paper describes the structure of the new course and reports on the evaluation results, which confirm that carefully structured hands-on experience is an effective way of motivating freshmen. Evaluation results also indicate that the course has increased student creativity and confidence. Since the lab course is just one credit, it appears possible to address the motivation problem without overloading already crowded first-year engineering programs. 相似文献
8.
S. T. B. Goennenwein T. Graf T. Wassner M. S. Brandt M. Stutzmann A. Koeder S. Frank W. Schoch A. Waag 《Journal of Superconductivity and Novel Magnetism》2003,16(1):75-78
We report on ferromagnetic resonance measurements of Ga1?x Mn x As thin films with Mn contents 0.022 ≤ x ≤ 0.051. For x ≥ 0.036 and the external magnetic field normal to the thin film, we observe several resonances, which we identify as spin wave resonances. The non-quadratic mode spacing can be consistently explained by a linear gradient in the magnetic properties of the films. From the measurements, the exchange constant A can be deduced for different Mn contents x. 相似文献
9.
The M1 Energy‐efficiency building Plus – Conclusion of monitoring / Das M1 Energieeffizienzhaus Plus – Abschluss des Monitorings
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Torsten Schoch Dipl.‐Ing. 《Mauerwerk》2015,19(2):93-109
The M1 energy‐efficiency building Plus was to render practical proof that the advantages of solid construction such as carrying capacity, fire protection and sound protection could be connected to state‐of‐the‐art and future energy efficiency standards in the scope of a pilot project. With simple and thought‐through planning details and a coordinated system technology, energy plus solid houses are no longer merely visions. The M1 project mostly focuses on the claim to economic efficiency and saleability of the product, points out new possibilities for implementation to consumers, planners and executing companies. The house is to document, that the means available now are sufficient to construct a solid building that produces more energy than it consumes. In the technical term of construction physics, the building is targeted at a negative final energy and primary energy consumption. The data presented in this article from the monitoring of the last two years show that a plus energy target can be achieved by “nearly” conventionally built solid buildings. For both years, the M1 pus energy house reached an excess of final and primary energy. 相似文献
10.