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Non-sticking droplets wrapped with fine hydrophobic particles, namely liquid marbles, can be transported both on solid and water pool without an undesired spill of the inner encapsulated liquid. While the stimuli-responsive release of the inner liquid in the target area is proposed, the time-programmed release is not yet achieved. Herein, the hydrophobicity of nanoclay is modulated via a catalyst-free 1,4-conjugate addition reaction to form liquid marbles. This nanoclay liquid marble is robust and stable in air but collapses on the liquid pool with a specific lifetime. The lifetime of the liquid marble can be modulated over seconds to hours scale depending on the selection of chemically modulated wettability of the nanoclay. The critical mechanism of lifetime modulation is responsible for controlling the coalescence kinetics between the water pool and inner liquid by nanoclays’ high diffusion length and chemically varied water spreading potential. The NC liquid marble's programmable lifetime to ‘time-bomb’ type drug release and cascade chemical reaction is applied—without requiring any external intervention.  相似文献   
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The retina is a tiny layer at the posterior pole of an eye and is made up of tissues sensitive to light, these tissues generate nerve signals that pass through the optic nerve to the brain. A retinal disorder occurs when the retina malfunctions; glaucoma, diabetic retinopathy and pathologic myopia are retinal disorders and principal causes of blindness worldwide. These retinal disorders are often diagnosed and treated by an ophthalmologist. However, to accurately assess a retinal disease, ophthalmologist would need qualitative and quantitative analysis of the disease, it’s early and current statistics, but acquisition of these measurements are not possible through manual techniques, there should be automated computer aided diagnosis (CAD) systems to assist ophthalmologists. In this comprehensive review, an analysis and evaluation has been performed of different computer vision and image processing approaches applied to OCT images for automatic diagnosis of retinal disorders. We also reported disease causes, symptoms and pathologies manifestations within OCT images, which can serve as baseline knowledge for development of an automated CAD system. Hence, this disease specific review offers a good understanding to analyze visual impairments from retinal OCT images which will help researcher to design enhanced therapeutic systems for retinal disorders.  相似文献   
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Our objective was to establish an in vitro cell culture protocol to improve bone cell attachment and proliferation on Ti substrate using direct current stimulation. For this purpose, a custom made electrical stimulator was developed and a varying range of direct currents, from 5 to 25 μA, was used to study the current stimulation effect on bone cells cultured on conducting Ti samples in vitro. Cell–material interaction was studied for a maximum of 5 days by culturing with human fetal osteoblast cells (hFOB). The direct current was applied in every 8 h time interval and the duration of electrical stimulation was kept constant at 15 min for all cases. In vitro results showed that direct current stimulation significantly favored bone cell attachment and proliferation in comparison to nonstimulated Ti surface. Immunochemistry and confocal microscopy results confirmed that the cell adhesion was most pronounced on 25 μA direct current stimulated Ti surfaces as hFOB cells expressed higher vinculin protein with increasing amount of direct current. Furthermore, MTT assay results established that cells grew 30% higher in number under 25 μA electrical stimulation as compared to nonstimulated Ti surface after 5 days of culture period. In this work we have successfully established a simple and cost effective in vitro protocol offering easy and rapid analysis of bone cell–material interaction which can be used in promotion of bone cell attachment and growth on Ti substrate using direct current electrical stimulation in an in vitro model.  相似文献   
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Journal of Materials Science - We report upon synthesis of stable chains of magnetically aligned zero-valent α-Fe nanoparticles and investigation of their magnetization reversal mechanism. The...  相似文献   
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Here we report the preparation and characterization of a green composite based on high‐density polyethylene and Kaans grass (Saccharum spontaneum). The composites were prepared by conventional melt‐mixing method, using maximum loading of Kaans grass in powder form (KG‐filler) to achieve acceptable range of required properties. Maleic anhydride grafted polyethylene was used as compatibilizer to achieve effective interaction for improved surface adhesion which was confirmed by FT‐IR spectroscopy. Morphological studies revealed good interaction between the base polymer matrices and the KG‐fillers that improved the mechanical and thermal properties of the composites up to certain (10 phr) KG‐filler loading. Study on water absorption property revealed moderate increase in weight at higher KG‐filler loadings. Thermogravimetric analysis (TGA) and melt flow index (MFI) studies indicated retention of thermal stability and flow property of the HDPE/KG‐filler composite at lower filler loadings. POLYM. COMPOS., 36:2157–2166, 2015. © 2014 Society of Plastics Engineers  相似文献   
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In the present work, a numerical study is performed to predict the transport phenomena during continuous casting of an aluminum alloy (A356) in presence of weak stirring. A set of volume averaged single phase conservation equations (mass, momentum, energy and species) is used to represent the casting process. The electromagnetic forces are incorporated in the momentum equations. The governing equations are solved based on the pressure-based finite volume method according to the SIMPLER algorithm using TDMA solver along with an enthalpy update scheme. The simulation predicts the temperature, solid fraction and species in the computational domain. A parametric study is also performed.  相似文献   
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In this work, we report a green method for the synthesis of gold nanoparticles (GNP) using the aqueous extract of red tomato (Lycopersicon esculentum). We believe that citric acid and ascorbic acid present in tomato juice are responsible for the reduction of gold ions. This biosynthesized GNP in the presence of sodium dodecyl sulfate has been used as a colorimetric sensor to detect and estimate the pesticide, methyl parathion. The GNP in the presence of methyl parathion shows a new peak at 400 nm due to the formation of 4-nitrophenolate ion by catalytic hydrolysis of methyl parathion in alkaline medium. A calibration curve between the absorption coefficients of the 400-nm peak versus the concentration of the pesticide allows the quantitative estimation of the 4-nitrophenolate ion, thereby enabling indirect estimation of methyl parathion present in the system.  相似文献   
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