Controllability and local accessibility - a normal form approach

Given a system with an uncontrollable linearization at the origin, we study the controllability of the system at equilibria around the origin. If the uncontrollable mode is nonzero, we prove that the system always has other equilibria around the origin. We also prove that these equilibria are linearly controllable provided a coefficient in the normal form is nonzero. Thus, the system is qualitatively changed from being linearly uncontrollable to linearly controllable when the equilibrium point is moved from the origin to a different one. This is called a bifurcation of controllability. As an application of the bifurcation, systems with a positive uncontrollable mode can be stabilized at a nearby equilibrium point. In the last part of this paper, simple sufficient conditions are proved for local accessibility of systems with an uncontrollable mode. Necessary conditions of controllability and local accessibility are also proved for systems with a convergent normal form.     

Simplifying pattern recognition problems via a scatter search algorithm

This article presents an approach to simplify pattern recognition problems via a scatter search algorithm that is applied as feature subset selector (FSS). Experimentation on five high-dimensionality problems, with a feature space in the range 2308–16063 and feature-to-pattern ratios greater than 27, revealed that the most appropriate feature selector is based on correlation. Moreover, the most accurate way is to combine the new proposal with a correlation-based attribute evaluator with a Naive Bayes Tree classifier; their performance has been compared with a reference FSS and sheds light on very interesting results in terms of accuracy and problem reduction.     

高层建筑二维流场的数值模拟

针对建筑物风场的高雷诺数特点,采用离散涡法,分析了高层建筑物的非定常分离流问题.通过引入奇异点技术摆脱了保角变换的处理过程,使离散涡法能适应于复杂形状的钝体结构.数值模拟了流场的变化特征,分析了各种攻角下,具有方形截面的高层建筑的升力系数、抗力系数和Strouhal数.计算分析表明,离散涡法具有计算速度快及精度高的特点,可以刻画出流场的流动特征,透视到流动机理,在结构风工程领域具有较好的应用价值.     

Nonlinearizable single-input control systems do not admit stationary symmetries

The main result of the paper states that almost any analytic single-input control system, which is truly nonlinear, that is not feedback linearizable, with controllable linearization at an equilibrium point, does not admit any symmetry preserving that point. By almost any system, we mean that we exclude a small class of odd systems, that admit just one nontrivial symmetry conjugated to minus identity. The obtained results are based on a recent classification of nonlinear single-input systems under formal feedback. We also describe symmetries of feedback linearizable systems.     

Strict feedforward control systems,linearisability, and convergent normal forms

This article discusses the feedback equivalence of multi-inputs feedforward control systems via smooth (resp. analytic) feedback transformations. We first address the state (resp. feedback) linearisation problem, and provide easily computable algorithms that yield explicit state (resp. feedback) linearising coordinates for systems in strict feedforward form. The application of the algorithms does not require checking the commutativity (resp. involutivity) of the distributions associated with the system, and the algorithms fail after few steps if the system is not linearisable. In the latter case, the algorithms are extended to provide coordinate systems bringing the system into a normal form which is a smooth (resp. analytic) counterpart of Kang's formal normal form. Illustrative examples for both the linearisation and convergent normal form include the vertical take off and landing aircraft, the multi-vehicle wireless testbed among others.     

A two-stage algorithm in evolutionary product unit neural networks for classification

This paper presents a procedure to add broader diversity at the beginning of the evolutionary process. It consists of creating two initial populations with different parameter settings, evolving them for a small number of generations, selecting the best individuals from each population in the same proportion and combining them to constitute a new initial population. At this point the main loop of an evolutionary algorithm is applied to the new population. The results show that our proposal considerably improves both the efficiency of previous methodologies and also, significantly, their efficacy in most of the data sets. We have carried out our experimentation on twelve data sets from the UCI repository and two complex real-world problems which differ in their number of instances, features and classes.     

Physical limitations on Salmonella typhi entry into cultured human intestinal epithelial cells

Kinetic studies of Salmonella typhi invasion of INT407 cells at different multiplicities of infection (MOIs) have revealed a strict physical limitation on S. typhi entry at MOIs of >/=40. Staining of infected monolayers to distinguish intracellular from extracellular bacteria revealed that all monolayer cells are susceptible to infection and that internalized bacteria are typically contained in one to three separate clusters per cell during the first 60 min. Scanning and transmission electron microscopic analyses of time course-infected monolayers showed that at early times postinfection, bacteria bind to shortened, coalesced microvilli in one to three focal aggregate structures per host cell surface. As reported previously for S. typhimurium, focal aggregates progress to conical membrane ruffles that appear to engulf one or a few centrally contained S. typhi cells by a macropinocytic process, which enhanced the entry of simultaneously added Escherichia coli HB101 about 30-fold. Additionally, kinetic studies showed that at an MOI of approximately 400, maximal S. typhi entry is virtually completed within 30 to 35 min. Monolayers pretreated with S. typhi for 30 min to saturate the entry process were severely reduced in the ability to internalize subsequently added kanamycin-resistant strains of S. typhi or S. typhimurium, but E. coli HB101(pRI203) expressing the cloned Yersinia inv gene was not reduced in entry. In invasion inhibition assays, anti-beta1 integrin antibodies markedly reduced E. coli HB101(pRI203) invasion efficiency but did not reduce S. typhi entry. Collectively, these data provide direct physical and visual evidence which indicates that S. typhi organisms are internalized at a limited number (i.e., two to four) of sites on host cells. S. typhi and S. typhimurium likely share INT407 cell entry receptors which do not appear to be members of the beta1 integrin superfamily.     

Cerebrospinal fluid levels of alpha-tocopherol (vitamin E) in Parkinson's disease

We compared CSF and serum levels, and the CSF/serum ratio of alpha-tocopherol (vitamin E), measured by HPLC, in 34 patients with Parkinson's disease (PD) and 47 controls. CSF and serum vitamin E levels were correlate. The mean CSF and serum vitamin E levels, and the CSF/serum ratio of PD patients did not differ significantly between the groups. There was no influence of antiparkinsonian therapy on CSF vitamin E levels. CSF vitamin E levels did not correlate with age, age at onset, duration of the disease, scores of the Unified Parkinson Disease Rating Scale of the Hoehn and Yahr staging in the PD group. These results suggest that CSF vitamin E concentrations are unrelated with the risk for PD.     

Increased coronary heart disease in Japanese-American men with mutation in the cholesteryl ester transfer protein gene despite increased HDL levels

Plasma high density lipoprotein (HDL) levels are strongly genetically determined and show a general inverse relationship with coronary heart disease (CHD). The cholesteryl ester transfer protein (CETP) mediates the transfer of cholesteryl esters from HDL to other lipoproteins and is a key participant in the reverse transport of cholesterol from the periphery to the liver. A high prevalence of two different CETP gene mutations (D442G, 5.1%; intron 14G:A, 0.5%), was found in 3,469 men of Japanese ancestry in the Honolulu Heart Program and mutations were associated with decreased CETP (-35%) and increased HDL chol levels (+10% for D442G). However, the overall prevalence of definite CHD was 21% in men with mutations and 16% in men without mutations. The relative risk (RR) of CHD was 1.43 in men with mutations (P < .05); after adjustment for CHD risk factors, the RR was 1.55 (P = .02); after additional adjustment for HDL levels, the RR was 1.68 (P = .008). Similar RR values were obtained for the D442G mutation alone. Increased CHD in men with mutations was primarily observed for HDL chol 41-60 mg/dl; for HDL chol > 60 mg/dl men with and without mutations had low CHD prevalence. Thus, genetic CETP deficiency appears to be an independent risk factor for CHD, primarily due to increased CHD prevalence in men with the D442G mutation and HDL cholesterol between 41 and 60 mg/dl. The findings suggest that both HDL concentration and the dynamics of cholesterol transport through HDL (i.e., reverse cholesterol transport) determine the anti-atherogenicity of the HDL fraction.     

Load balancing routing with queue overflow prediction for WSNs

The ease of deployment of Wireless Sensor Networks (WSNs) makes them very popular and useful for data collection applications. Nodes often use multihop communication to transmit data to a collector node. The next hop selection in order to reach the final destination is done following a routing policy based on a routing metric. The routing metric value is exchanged via control messages. Control messages transmission frequency can reduce the network bandwidth and affect data transmission. Some approaches like trickle algorithm have been proposed to optimize the network control messages transmission. In this paper, we propose a collaborative load balancing algorithm (CoLBA) with a prediction approach to reduce network overhead. CoLBA is a queuing delay based routing protocol that avoids packet queue overflow and uses a prediction approach to optimize control messages transmission. Simulation results on Cooja simulator show that CoLBA outperforms other existing protocols in terms of delivery ratio and queue overflow while maintaining a similar end-to-end delay.