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排序方式: 共有682条查询结果,搜索用时 15 毫秒
1.
K Hisatomi N Hayashida E Tayama M Ohashi T Isomura K Kosuga K Oishi 《Canadian Metallurgical Quarterly》1993,94(8):791-795
Glucagon has been demonstrated to stimulate the uptake of bile acid in isolated rat hepatocytes (Am. J. Physiol., 249, G427 (1985)). In the present study, we determined the influence of glucagon on the hepatic transport of a bile acid, taurocholate (TCA), in isolated rat livers. A single-pass perfusion and a rapid-injection, multiple indicator dilution method were employed. The hepatic availability at steady-state was 0.04. With the presence of glucagon in the perfusate (from 10(-9) to 10(-7) M), the bile flow rate was stimulated by 30%, while hepatic availability was decreased from 0.04 to 0.02 with a stepwise increase in glucagon concentration. Thirty min after the infusion of glucagon (300 nM), [3H]TCA and [14C]inulin were injected in a bolus state into the portal vein, and the outflow was collected at 1.0 s intervals over 30 s. Glucagon decreased the instantaneous hepatic availability by 50% compared to the control level, and was thus compatible with the steady-state experiments. In the control experiment, the influx clearance (PSinf) was 20 times higher than the efflux clearance (PSeff). Glucagon (300 nM) in the perfusate enhanced PSinf by 50% of the control, whereas sequestration clearance (CLseq) and the biliary excretion rate constant remained unchanged. PSeff was stimulated to 2 times the control, but still remained much smaller than CLseq. Based on the comparison of PSinf, PSeff and CLseq, the rate-determining process of TCA hepatic elimination was the influx process in both the presence and absence of glucagon. Taken together, the enhancement of the influx process was responsible for the decrease in TCA hepatic availability caused by glucagon.(ABSTRACT TRUNCATED AT 250 WORDS) 相似文献
2.
Oishi Shigehiro; Diener Ed; Choi Dong-Won; Kim-Prieto Chu; Choi Incheol 《Canadian Metallurgical Quarterly》2007,93(4):685
The authors examined cultural and individual differences in the relation between daily events and daily satisfaction. In a preliminary study, they established cross-cultural equivalence of 50 daily events. In the main study, participants in the United States, Korea, and Japan completed daily surveys on the 50 events and daily satisfaction for 21 days. The multilevel random coefficient model analyses showed that (a) the within-person association between positive events and daily satisfaction was significantly stronger among Asian American, Korean, and Japanese participants than among European American participants and (b) the within-person association between positive events and daily satisfaction was significantly weaker among individuals high in global life satisfaction than among those low in global life satisfaction. The findings demonstrate a weaker effect of positive events on daily well-being among individuals and cultures high in global well-being. (PsycINFO Database Record (c) 2010 APA, all rights reserved) 相似文献
3.
Yushi Shen Pamela C Cosman Laurence B Milstein 《IEEE transactions on image processing》2006,15(11):3241-3252
We present an adaptive video transmission scheme for use in a code-division multiple-access network, which incorporates efficient bandwidth allocation among source coding, channel coding, and spreading under a fixed total bandwidth constraint. We derive the statistics of the received signal, as well as a theoretical bound on the packet drop rate at the receiver. Based on these results, a bandwidth allocation algorithm is proposed at the packet level, which incorporates the effects of both the changing channel conditions and the dynamics of the source content. Detailed simulations are done to evaluate the performance of the system, and the sensitivity of the system to estimation error is presented. 相似文献
4.
相较于传统的脉宽调制技术,随机脉宽调制具备有效的谐波频谱分散能力,从而实现机电负载噪声的削弱。随机脉宽调制技术包括起步的随机开关调制、后续的随机脉冲位置与随机开关频率等3个基本方法。随着电力电子技术的整体发展,随机脉宽调制已从传统的载波调制逐渐拓展到空间矢量调制之中,应用范围日趋广泛,谐波频谱分散与功率谱峰值抑制的效果不断提升。同时,新的优化方案不断被提出,对谐波频谱及功率谱的分散效果亦在不断提高。梳理了随机脉宽调制的研究历程,总结了数种典型的随机脉宽调制的基本原理,并对未来随机脉宽调制的研究方向作出展望,为随机脉宽调制技术的深入研究提供参考。 相似文献
5.
Kunio Mori Wataru Ibashi Hidetoshi Hirahara Yoshiyuki Oishi Masanari Katayama 《应用聚合物科学杂志》1995,58(13):2451-2458
2-Dibutylamino-1,3,5-triazine-4,6-dithiol (DB) and a mixture of DB and triallylisocyanurate (TAIC) were used as a lubricant during steel wire drawing due to a dry process. DB gave a polymer film with 180 nm in thickness to wire surfaces during the wire drawing. The polymer film had a disulfide structure on the backbone and contained a small amount of DB monomer and olygomer. Molecular weight and polymer weight increased with the drawing rate. The mixture of DB and TAIC gave mainly a three-dimensional polymer film with 225 nm in thickness to wire surfaces during drawing. The polymer film insoluble in THF had mono and disulfide structures and contained a small amount of linear polymer, DB, and TAIC. Such tribological polymerizations are estimated as follows: DB produces dithiyl radicals on a nascent surface formed during drawing and in the presence of oxygen and heat. The dithiyl radicals were polymerized by coupling with each other to give disulfide bonds or added to allyl groups in TAIC to give monosulfide bonds. It is concluded that this technique should be possible to use for unifying metal processing and surface treatment. © 1995 John Wiley & Sons, Inc. 相似文献
6.
In order to develop an energy-saving copper recycling process from wastes, electrochemical measurements were conducted in ammoniacal alkaline solutions containing Cu(I) ions and an ammonium salt of sulfate, chloride or nitrate. The results of each system were then compared. The polarization measurements suggested that the voltage required for the electrode process is lower in the chloride and nitrate systems than that in the sulfate system. The cathode current efficiency during the copper electrodeposition varied from 39 to 97% and increased with current density in the chloride and sulfate systems. In the nitrate system, the lowest cathode current efficiency of 30% was observed because of nitrate ion reduction. Based on these results, the power consumption required for the electrowinning stage of the copper recycling process was calculated. Among these three systems, the chloride system showed the lowest power consumption of 500 kWh t−1 at the current density of 200 A m−2, which is about 25% of the conventional copper electrowinning process from a copper sulfate-sulfuric acid solution. 相似文献
7.
8.
Gallium activity in the B2 phase regions of both binary Co–Ga and ternary Co–Ga–Sb systems was measured by EMF method with stabilized zirconia solid electrolyte The temperature range was 1073–1273 K and Sb concentrations were 1, 2 and 3 mol fractions. Ga activity at 1173 and 1273 K increases sharply in Ga rich region and the addition of Sb to the CoGa phase increases Ga activity. Activity change corresponds to the lattice parameter change with Sb addition to the CoGa phase. 相似文献
9.
Bo Zheng Ryo Ishikawa Jun Takamatsu Takeshi Oishi Katsushi Ikeuchi 《Computer Vision and Image Understanding》2013,117(12):1647-1658
A fast registration making use of implicit polynomial (IP) models is helpful for the real-time pose estimation from single clinical free-hand Ultrasound (US) image, because it is superior in the areas such as robustness against image noise, fast registration without enquiring correspondences, and fast IP coefficient transformation. However it might lead to the lack of accuracy or failure registration.In this paper, we present a novel registration method based on a coarse-to-fine IP representation. The approach starts from a high-speed and reliable registration with a coarse (of low degree) IP model and stops when the desired accuracy is achieved by a fine (of high degree) IP model. Over the previous IP-to-point based methods our contributions are: (i) keeping the efficiency without requiring pair-wised correspondences, (ii) enhancing the robustness, and (iii) improving the accuracy. The experimental result demonstrates the good performance of our registration method and its capabilities of overcoming the limitations of unconstrained freehand ultrasound data, resulting in fast, robust and accurate registration. 相似文献
10.
Boosted Bayesian network classifiers 总被引:2,自引:0,他引:2
The use of Bayesian networks for classification problems has received a significant amount of recent attention. Although computationally
efficient, the standard maximum likelihood learning method tends to be suboptimal due to the mismatch between its optimization
criteria (data likelihood) and the actual goal of classification (label prediction accuracy). Recent approaches to optimizing
classification performance during parameter or structure learning show promise, but lack the favorable computational properties
of maximum likelihood learning. In this paper we present boosted Bayesian network classifiers, a framework to combine discriminative
data-weighting with generative training of intermediate models. We show that boosted Bayesian network classifiers encompass
the basic generative models in isolation, but improve their classification performance when the model structure is suboptimal.
We also demonstrate that structure learning is beneficial in the construction of boosted Bayesian network classifiers. On
a large suite of benchmark data-sets, this approach outperforms generative graphical models such as naive Bayes and TAN in
classification accuracy. Boosted Bayesian network classifiers have comparable or better performance in comparison to other
discriminatively trained graphical models including ELR and BNC. Furthermore, boosted Bayesian networks require significantly
less training time than the ELR and BNC algorithms. 相似文献