飞来峰

北宋诗人王安石有“登飞来峰”诗句——“不畏浮云遮望眼,只缘身在最高峰。”作品由三个四边形构成双曲面向心围合的亭子结构,三个基点既是整体的支撑又是三个主体结构的结合点,三个尖锐峰顶在12米高处一齐指向天空,大器浑然天成：三个尾翼翘起伸向远方,彰显出一种飞扬的动势,表现出高远律动而张扬不羁的风格。     

优雅起伏的空间整合（优秀奖）

我们的设计显示了计算机辅助设计和参数化研究如何在规划过程中引导识别性、协同性和可持续性的发展。我们的规划非常关注景观和地面组织,设计有一个各种集群活动的总体分配方式,这种方式同等地回应了周边环境和预期经济协作活动。我们的设计启示来源于场地景观及延庆的创新工业的雄心。在规划过程中．我们组织了密切合作的专家团队．集合了建筑、景观和技术工程的共同智慧．以达到上述这些原则。     

Effects of passive smoking on the regulation of rat aortic cholesteryl ester hydrolases by signal transduction

The effects of exogenous oxidative stress due to passive smoking on cholesteryl ester (CE)-metabolizing enzymes and their regulatory kinases were examined by exposing rats to cigarette smoke (CS) for a 1-h period twice a day for 8, 12, or 20 wk. An oxidatively modified low density lipoprotein (Ox-LDL) with a high lipid peroxide was identified in three CS groups after all three exposure periods. The rat aortic acid and neutral CE hydrolases (ACEH and NCEH) were activated to similar extents by both cAMP-dependent protein kinase (PKA) and protein kinase C (PKC) in the presence of their respective cofactors. The aortic PKC activity in the three CS groups exhibited significant reductions of 72, 84, and 75% as compared with the respective controls, which coincided with the reductions in the ACEH activities (86, 71, and 80%, respectively), whereas the PKA activities increased to 121, 197, and 252% in the three CS groups, respectively. Reflecting the increase of the PKA activity, the NCEH activity exhibited increases of 112% at 8 wk and 140% until 12 wk of exposure and decreased by 50% of the control value at 20 wk of exposure, suggesting inactivation of NCEH itself. The activation of acyl-CoA:cholesterol O-acyl-transferase activity was associated with an increase of free cholesterol in aorta. The vitamin E diet prevented the formation of Ox-LDL and the oxidative inactivation of most enzymes, especially PKC, until 12 wk, but was less effective by 20 wk. The oxidative inactivation of PKC, particularly its activated form that translocated to the membrane fraction, was confirmed in the in vitro exposure to active oxygen generators at an optimal concentration; this inactivation was prevented by catalase and superoxide dismutase. These results suggested that the formation of Ox-LDL and alterations in CE-metabolizing enzymes caused by passive smoking could contribute to a twofold increase in the aortic CE content, thereby contributing to one of the mechanisms for atherosclerosis associated with smoking.     

Distribution of transposable elements in neotropical species of Drosophila

The phylogenetic distribution of transposable families, P, gypsy, hobo, I, and mariner has been analyzed in 33 species of 11 groups of neotropical Drosophila and a Drosophilidae species Zygotrica vittimaculosa, using squash blot and dot blot. Genomic DNA of almost all neotropical species tested hybridized with gypsy probe and some species showed a particularly strong hybridization signal, as D. gaucha, D. virilis, and species of flavopilosa group. The hobo element was restricted to melanogaster group and some strains of D. willistoni. Only D. simulans DNA showed hybridization to mariner probe in all species tested and D. simulans and D. melanogaster showed hybridization with I element probe. P element homologous sequence was present in D. melanogaster and all species and strains of the willistoni and saltans groups tested. The presence of at least one P-homologous sequence was detected in Drosophila mediopunctata. This one was the only P-bearing species of all six tested from the tripunctata group. Four different pairs of primers homologous to segments of the canonical sequence of D. melanogaster's P were used to amplify specific sequences from D. mediopunctata DNA, showing the occurrence of seemingly well-conserved P-homologous sequences.     

流·砾·韵

奔流的河谷、流水的侵蚀所产生的韵律凝结成一座建筑——广州大剧院,它的魅力在于将城市空间与流动的笔触交织在一起,将广州历史文化的传统、放眼未来的雄心和乐观的情绪结合在一起。大剧院项目建筑师Simon Yu形容这个工程是"难以置信的奇迹"。大剧院从开始设计到设计完成只用了一年半时间,而留给Zaha Hadid的时间更少。各个功能空间以及空间之间     

第一层:流动的线条

扎哈为酒店带来的第一层就是如此的与众不同,完全打破了传统印象中的建筑形式,一切都是流动的,蜿蜒曲折。电梯厅入口很窄,弯曲的线条和变化的颜色引人入胜。进入客房,风格不变,线条更加简练,颜色也采用了全白色,白色的墙,白色的桌椅。特别要说的是,客房门的上方特意安装了二级发光管照亮房门,目的是用不同的颜色表示客人的需要,早饭或者是“请勿打扰”。设计师还为她的作品设计了一个硕大无比的沙发椅,椅子的形状和房间里的线条非常般配。浴室是客房内惟一不是白色的地方,扎哈为它配置了颜色鲜亮的卤素灯,给客房加一点点浪漫气质。置身于扎…     

海芋（Arum）装置

2012年威尼斯建筑双年展的主题为“共同的基础”,显示了通常认为是独立个人创作的现代建筑的主角事实上是基于集体研究的历史血统的。这也是扎哈·哈迪德（Zaha Hadid）建筑事务所工作的真谛。最初的设想和灵感源于俄罗斯的至上主义。     

香港理工大学赛马会创新楼

赛马会创新楼是香港理工大学设计学院和赛马会社会创新设计院的总部.建筑地上15层,使用面积1 5万m2,可容纳1 800多名师生,楼内设有用于设计教学及创新的各种空间,包括设计工作室、实验室和创作室、展示区、多功能教室、报告厅和公共空间. 香港理工大学校园的规划建设持续了半个多世纪,不同学院的教学科研楼风格迥异,但在视觉上又相互协调.赛马会创新楼创造了一种全新的城市空间,丰富了多样的大学生活,同时也展现出设计学院面向未来的发展活力.