高效液相色谱-荧光检测器法测定白酒中尿素含量方法研究

建立一种利用高效液相色谱结合荧光检测器准确、快速测定白酒中微量尿素的方法。白酒样品经9-羟基吨在酸性、避光条件下衍生30 min后,直接进样分析。采用C18色谱柱分析,流动相为乙腈和0.02 mol/L乙酸钠溶液(p H7.2),检测器波长为λex=213 nm,λem=308 nm。方法在线性范围内相关系数R2=0.9999;检测限和定量限分别为0.021 mg/L和0.071 mg/L;平均回收率及回收率相对标准偏差(RSD)分别为97.71%和3.61%;日内和日间精密度分别为1.63%和1.98%。该方法方便快速,精度高、分离度好,适合于白酒中微量尿素的测定。     

铁路无砟轨道挡台填充聚氨酯树脂的研制

以HTPB和聚醚掺混的多元醇、TDI和改性MDI为主要原料合成了预聚体,然后以胺作扩链剂,合成了无砟轨道挡台填充聚氨酯树脂。产品的工艺和使用性能达到了暂行技术条件(科技基[2008]74号)的要求,满足了我国铁路客运专线的需要。     

基于匹配追踪稀疏分解的电能质量扰动检测

根据基于冗余字典的匹配追踪(MP)信号分解思想,提出一种电能质量扰动信号的参数检测与特征波形提取方法。在MP算法的每次迭代中,首先采用快速傅里叶变换(FFT)搜索能量最大的频率成分,然后采用基于离散Gabor原子中心区域的简化内积计算方法获得扰动参数的估计值,并以该估计值作为初始解,采用BFGS算法做局部搜索,进而获得精确匹配参数,并结合基于递归的内积计算确定扰动的起止时刻,最后根据电力信号扰动波形特点,设计合成字典,确定与扰动成分最匹配的波形。对单一和混合电能质量扰动信号的分解实验表明,该方法可以实现扰动参数的快速精确检测,进而有效提取扰动特征波形,并具有较好的抗噪性能。     

铬锰硅合金代替铜生产汽缸体

在铁水包中加入廉价的铬锰硅合金代替贵重金属铜生产汽缸体，取得显著的经济效益。     

Combined addition of glutathione and iron chelators for decrease of intracellular level of reactive oxygen species and death of Chinese hamster ovary cells

The combined addition of reduced form of glutathione (GSH) and iron chelators for decrease of the intracellular level of reactive oxygen species (ROSs) and death of Chinese hamster ovary (CHO) cells was investigated. The addition of GSH to the serum-free cultures of CHO cells markedly lowered the intracellular ROS level, which effect was comparable to that of the addition of serum (0.4, 10%) and might be due to the reduction of ROS. The addition of iron chelators, deferoxamine and aurintricarboxylic acid, to the serum-free cultures also decreased the intracellular ROS level and increased the residual concentration of viable cells during the serum-free maintenance culture, which should be due to the inhibition of the Fenton and Harber-Weiss reactions stimulating the synthesis of ROS. The combined addition of GSH and the chelators decreased ROS level and cell death more effectively compared with their single addition.     

磨矿分级控制系统方案设计

依据选矿科研成果和国家行业标准,在系统分析石录原生铜矿磨矿工艺的基础上,全面研讨分级磨矿工艺自动化解决方案。     

Preparation of novel porous starch microsphere foam for loading and release of poorly water soluble drug

Background: Organic porous material is a promising carrier for enhancing the dissolution of poorly water soluble drug. The aim of the present study was to enhance dissolution and oral bioavailability of lovastatin (LV) by preparing a porous starch microsphere foam (PSM) using a novel method, meanwhile, looking into the mechanism of improving dissolution of LV.

Methods: PSM was prepared by the W/O emulsion – freeze thawing method. The porous structure of PSM was characterized by scanning electron microscopy (SEM) and nitrogen adsorption/desorption analysis. The adsorption role of nanopores on the drug dissolution and physical state of LV was systematically studied by instrumental analysis, and in vitro and in vivo drug dissolution studies. 3-(4,5-Dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay was used to evaluate carrier cytotoxicity.

Results: The SEM images of PSM showed nanometer-sized pores. Physical state characterization indicated that porous structure effectively limited the degree of crystallinity of LV. The results of in vitro and in vivo tests testified that PSM accelerated the release of LV and enhanced its oral bioavailability in comparison with crude LV and commercial capsules. The loaded PSM powder indicated a good physical stability under storage for 12 months. MTT assay shows PSM has no toxicity for Caco-2 cell.

Conclusion: The preparation was a promising method to produce small and uniform PSM with markedly enhanced dissolution rate and oral bioavailability due to the spatial confinement effect of porous structure. The present work demonstrates the significant potential for the use of PSM as a novel delivery system for poorly water soluble drugs.     

硼锰矿生产硼酸和碳酸锰的半工业试验研究

阐述了由硼锰矿生产硼酸和碳酸锰的半工业试验结果。采用酸浸可同时浸出硼和锰，浸出率９７％以上，在高酸和高锰溶液中冷冻得硼酸，品位大于９８％，采用针铁矿法除铁与碳酸氢铵沉锰后获得品位达９８％的碳酸锰产品。     

预钻孔措施对静压桩挤土效应的影响分析

桩位处预钻孔是工程中减弱沉桩挤土效应的有效措施之一。根据Drucker-Prager破坏准则及有限变形理论,建立了桩–土相互作用及连续贯入的有限元模型,利用得到的模型模拟了预钻孔措施下沉桩产生的挤土位移场,并和现场实测进行了对比。结果表明,预钻孔的孔径与孔深是影响静压桩挤土效应的重要因素,二者的结合会更有效地减少挤土效应的广度和深度。在同样孔深情况下,随着孔径的增大,所产生的挤土位移相应减小;相同孔径情况下,孔越深产生的挤土效应就越小。     

光伏组件受雷电影响的因数检测及仪器选择

鉴于雷电对太阳能光伏系统具有危害性,针对目前光伏发电系统专业防雷系统标准尚待完善,缺乏针对光伏发电防雷系统的专业检测设备,以及光伏发电防雷控制系统知识的专业培训,同时光伏组件设计生产过程中,没有将防雷检测作为产品设计检测的必备环节等现状,对光伏发电系统防雷结构设计及仪器选择进行阐述。本文简要叙述了雷电对光伏发电系统的危害及雷电分类,详细阐述了光伏发电系统防雷结构装置的设计方案,光伏发电系统监测方式以及光伏发电系统所需的检测仪器。