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Optical Waveguides: Flexible Transient Optical Waveguides and Surface‐Wave Biosensors Constructed from Monocrystalline Silicon (Adv. Mater. 32/2018)
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Flexible Transient Optical Waveguides and Surface‐Wave Biosensors Constructed from Monocrystalline Silicon
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Wubin Bai Hongjun Yang Yinji Ma Hao Chen Jiho Shin Yonghao Liu Quansan Yang Irawati Kandela Zhonghe Liu Seung‐Kyun Kang Chen Wei Chad R. Haney Anlil Brikha Xiaochen Ge Xue Feng Paul V. Braun Yonggang Huang Weidong Zhou John A. Rogers 《Advanced materials (Deerfield Beach, Fla.)》2018,30(32)
Optical technologies offer important capabilities in both biological research and clinical care. Recent interest is in implantable devices that provide intimate optical coupling to biological tissues for a finite time period and then undergo full bioresorption into benign products, thereby serving as temporary implants for diagnosis and/or therapy. The results presented here establish a silicon‐based, bioresorbable photonic platform that relies on thin filaments of monocrystalline silicon encapsulated by polymers as flexible, transient optical waveguides for accurate light delivery and sensing at targeted sites in biological systems. Comprehensive studies of the mechanical and optical properties associated with bending and unfurling the waveguides from wafer‐scale sources of materials establish general guidelines in fabrication and design. Monitoring biochemical species such as glucose and tracking physiological parameters such as oxygen saturation using near‐infrared spectroscopic methods demonstrate modes of utility in biomedicine. These concepts provide versatile capabilities in biomedical diagnosis, therapy, deep‐tissue imaging, and surgery, and suggest a broad range of opportunities for silicon photonics in bioresorbable technologies. 相似文献
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