Performance analysis of linear precoding based on field trials results of MIMO-OFDM system

We use field trial results obtained from a multiple-input multiple-output (MIMO) orthogonal frequency-division multiplexing (OFDM) wireless system with two transmitter and three receiver antennas (2/spl times/3), to first validate the properties of the transmit correlation matrix in a macro-cellular environment. We find that approximately 20% of the locations have well-defined transmit correlation matrices. Furthermore, the eigenvectors of the transmit correlation matrix vary slowly over distance with 60% of the locations having eigenvector variation of less than 1 dB over a distance of 20 m. Next, we quantify the performance of the optimal statistical linear precoding (OSLP) , and statistical one-dimensional (1-D) eigenbeamforming (SEB) based on transmit correlation matrices, and the 1-D eigenbeamforming (EB)-based on perfect channel knowledge at the transmitter. We find that the OSLP and SEB schemes obtain array gain over the Alamouti scheme at lower signal-to-noise ratio (SNR) with a median gain of 2.0 (1.5) dB at the 1.0-(3.5) km cell-radii. However, the SEB scheme (unlike the OSLP scheme) looses diversity order at higher SNR that leads to a performance loss. The EB scheme provides the best performance over the Alamouti scheme, at the expense of increased feedback requirements.     

Fodor and Pylyshyn on connectionism

Fodor and Pylyshyn (1988) have argued that the cognitive architecture is not Connectionist. Their argument takes the following form: (1) the cognitive architecture is Classical; (2) Classicalism and Connectionism are incompatible; (3) therefore the cognitive architecture is not Connectionist. In this essay I argue that Fodor and Pylyshyn's defenses of (1) and (2) are inadequate. Their argument for (1), based on their claim that Classicalism best explains the systematicity of cognitive capacities, is an invalid instance of inference to the best explanation. And their argument for (2) turns out to be question-begging. The upshot is that, while Fodor and Pylyshyn have presented Connectionists with the important empirical challenge of explaining systematicity, they have failed to provide sufficient reason for inferring that the cognitive architecture is Classical and not Connectionist.     

Analysis and optimization of fixture under dynamic machining condition with chip removal effect

Dynamic interactions in the tool–workpiece and workpiece–fixture systems significantly impinge on the quality of finished workpieces. The presented simulation system integrates the effects of workpiece fixture dynamics with the other factors contributing to the machining process dynamics. It provides more accurate prediction of the process output which helps in the design of the optimum fixture configuration prior to the production stage. Modelling of the frictional contact behaviour between the fixture element and the workpiece helps to improve the prediction accuracy of the simulation system which accelerates the convergence to the optimum fixture configuration design and consequently improves the machined part dimensional accuracy and geometric integrity. The developed simulation is capable of modelling complicated part geometries by interfacing with commercial ANSYS.V10^® packages. This research work minimizes the deformation of workpiece using integrated optimization tool of Genetic algorithm (GA) and ANSYS Parametric Design Language (APDL) of finite element analysis. The same layouts given by the above optimization tool are used in the experimental setup and it is found that the improved geometric tolerance of squarness and flatness of the given workpiece. The chip removal effect and frictional contact between the workpiece and the fixture elements are taken into account based on element death technique and nonlinear finite-element analysis. A Case study of an open slot milling process illustrates the application of the proposed improved geometric tolerance approach.     

Corrosion of 2205 duplex stainless steel in chloride medium containing sulfate-reducing bacteria

Sulfate-reducing bacteria (SRB) play significant role in the corrosion of stainless steels exposed to marine and soil environment. Sulfate reduction by bacterial species results in the production of H₂S, which can significantly influence the anodic and cathodic processes and ultimately enhances the corrosion of materials. In the present study, 2205 type duplex stainless steel (DSS) coupons in solution-annealed condition were exposed to chloride medium containing SRB species, Desulfovibrio desulfuricans, for 40 days and examined by microscopy. Etching of the duplex structure, pitting as well as crevice attack were noticed. Similar results were obtained by microscopic studies with coupons exposed for 14 days in medium containing SRB followed by anodic polarization. SEM studies, of crevices observed after anodic polarization, indicated that the attack was initiated at the grain boundaries and slowly encroached into austenite grains. The initiation of attack was also evident from AFM studies of coupon exposed under freely corroding conditions for 7 days. ESCA studies reveal that under anaerobic conditions of SRB growth sulfidation of passive film occurs. The modified passive film found to depolarize the cathodic reactions. The nature and mechanism of SRB attack on DSS and possibility of detection at early stages were discussed.     

Cellulose-binding domains: potential for purification of complex proteins

The endoglucanase CenA and the exoglucanase Cex from Cellulomonasfimi each contain a discrete cellulose-binding domain (CBD),at the amino-terminus or carboxyl-terminus respectively. Thegene fragment encoding the CBD can be fused to the gene of aprotein of interest. Using this approach hybrid proteins canbe engineered which bind reversibly to cellulose and exhibitthe biological activity of the protein partner. Alkaline phosphatase(PhoA) from Escherichia coli, and a ß-glucosidase(Abg) from an Agrobacterium sp. are dimeric proteins. The fusionpolypeptides CenA-PhoA and Abg-CBC_cex are sensitive to proteolysisat the junctions between the fusion partners. Proteolysis resultsin a mixture of homo- and heterodimers; these bind to celluloseif one or both of the monomers carry a CBD, e.g. CenA-PhoA/CenA-PhoAand CenA-PhoA/PhoA. CBD fusion polypeptides could be used inthis way to purify polypeptides which associate with the fusionpartner.     

Book reviews

Electronic Finance Law Chris Reed, 1993 Hemel Hempstead: Woodhead‐Faulkner. 450 pp. £50.00

Introduction to Computer Law, 2nd Edn David I. Bainbridge, 1993 London: Pitman £18.99

Deontic Logic in Computer Science: normative system specification John‐Jules CH. Meyer & Roel J. Wieringa, 1993 London: John Wiley £34.95, xiv + 317pp.     

Foley catheters functionalised with a synergistic combination of antibiotics and silver nanoparticles resist biofilm formation

Foley catheters are inevitable in health care unit. Pathogens colonise and form biofilm on catheter causing catheter‐associated urinary tract infection. Therefore, the authors aimed to functionalise catheter to resist biofilm formation. The authors impregnated urinary catheters with a synergistic combination of antibiotics and silver nanoparticles (SNPs) to evaluate antibiofilm efficacy in vitro and in vivo. SNPs were synthesised using Spirulina platensis. Synergy between the SNPs and antibiotics was determined by the checker‐board method. In vivo efficacy of the functionalised catheters was assessed in mice. Liver and kidney function tests of mice were performed. The in vitro anti‐adherence activity of the functionalised catheters was evaluated after 2 years. Nanoparticle sizes were 42–75 nm. Synergistic activity was observed among SNPs (2 µg/ml), amikacin (6.25 µg/ml), and nitrofurantoin (31.25 µg/ml). In mice, catheters functionalised with combinations of antibiotics and SNPs exhibited no colonisation until Day 14. Blood, liver, and kidney tests were normal. After 2 years, catheters functionalised with antibiotics exhibited 25% inhibition of bacterial adhesion, and catheters functionalised with the nanoparticle‐antibiotic combination exhibited 90% inhibition. Impregnation of urinary catheters with a synergistic combination of antibiotics and SNPs is an efficient and promising method for preventing biofilm formation.Inspec keywords: catheters, drugs, silver, nanoparticles, nanomedicine, liver, kidney, blood, microorganisms, adhesion, biomechanics, cellular biophysicsOther keywords: Foley catheters, synergistic nanoparticle‐antibiotics combination, silver nanoparticles, biofilm formation resitance, health care unit, pathogens, urinary tract infection, SNP, Spirulina platensis, checker‐board method, liver function, kidney function, vitro antiadherence activity, amikacin, nitrofurantoin, blood, bacterial adhesion, size 42 nm to 75 nm, Ag