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1.
Here we report a case that presented with sudden onset of neurological symptoms and was treated with ganciclovir. Polymerase chain reaction analysis for human herpes virus-6 (HHV-6) from his cerebrospinal fluid was later found to be positive. He subsequently recovered with minimal residual neurological symptoms. Encephalitis secondary to this virus may be more common than previously thought in patients undergoing bone marrow transplantation. This condition should be considered in the differential diagnosis of sudden onset neurological symptoms after bone marrow transplantation.  相似文献   
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Weanling male Sprague-Dawley rats were fed diets for four weeks which differed in their content of n−6 (corn oil; CO) and n−3 fatty acids (fish oil; FO), but were similar in their content of saturated and monounsaturated fatty acids and vitamin E. At the end of the four-week feeding period, each dietary group was subdivided into two groups. One group received a single placebo injection of α-tocopherol-stripped corn oil (TSCO); the other group received a single injection of the free radical generator, methyl ethyl ketone peroxide (MEKP), in TSCO. Twenty-four hours after injection, the effect of dietary oil and MEKP treatment on endogenous lipid peroxide (LPO) production (measured as methylene blue formed by the “Determiner LPO” assay), glutathione (GSH) and vitamin E content, and fatty acid composition of phosphatidylcholine and phosphatidylethanolamine in heart and liver from unfasted animals were measured. FO-fed rats had significantly heavier hearts and livers, increased levels of n−3 fatty acids in membrane phospholipids, and higher liver LPO levels than CO-fed rats. MEKP treatment resulted in significantly lower body weights and liver GSH levels. The data indicate that dietary n−3 fatty acids increase lipid peroxidation in liver somewhat more than in heart. The study also demonstrates that the effect of induced oxidative stress due to a single dose of MEKP on lipid peroxide formation and antioxidant status in tissues from unfasted animals was independent of the dietary oils.  相似文献   
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This paper presents a new technique for mapping regional salt sources that has major implications for salinity management in southeastern Australia. This was achieved by analyzing a regional mosaic of airborne gamma-ray emission derivatives and verified by existing airborne electromagnetic and drilling data. A significant correlation was found between aeolian (windblown) materials, upland salts and gamma-ray signatures. This is consistent with the conceptual model that much of the salt in the upland areas of the Murray-Darling Basin is sourced from deposited aeolian materials that have been derived from deflationary events in salt-bearing landscapes in the western arid part of the basin. From gamma-ray emissions, and based on an observed relationship with borehole salinity, concentrated aeolian salt source deposits contained about 0.7% potassium and 10 ppm thorium. Using this signature on normalized data, an Euclidean distance algorithm provided mapping and information relating to salt-mobility pathways over a wide region. The resulting gamma-ray salt source model (GSM) facilitates focussed management of salinity infiltration zones in catchments across the basin.  相似文献   
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Adaptive diagnosis in distributed systems   总被引:5,自引:0,他引:5  
Real-time problem diagnosis in large distributed computer systems and networks is a challenging task that requires fast and accurate inferences from potentially huge data volumes. In this paper, we propose a cost-efficient, adaptive diagnostic technique called active probing . Probes are end-to-end test transactions that collect information about the performance of a distributed system. Active probing uses probabilistic reasoning techniques combined with information-theoretic approach, and allows a fast online inference about the current system state via active selection of only a small number of most-informative tests. We demonstrate empirically that the active probing scheme greatly reduces both the number of probes (from 60% to 75% in most of our real-life applications), and the time needed for localizing the problem when compared with nonadaptive (preplanned) probing schemes. We also provide some theoretical results on the complexity of probe selection, and the effect of "noisy" probes on the accuracy of diagnosis. Finally, we discuss how to model the system's dynamics using dynamic Bayesian networks (DBNs), and an efficient approximate approach called sequential multifault; empirical results demonstrate clear advantage of such approaches over "static" techniques that do not handle system's changes.  相似文献   
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This study tested the hypotheses that gender harassment is related to decreased job satisfaction and increased distress, and that White and minority women differ in their responses to it, in a sample of 385 women office workers. Over 70% reported exposure to gender harassment at work. As predicted, frequency of harassment was negatively correlated with job satisfaction and positively associated with an index of distress, assessed by self-reported somatic complaints, the Center for Epidemiological Studies Depression Scale (Radloff, 1997), and the reported use of alcohol for palliative coping. Minority status was unrelated to frequency of reported harassment or to responses to it. The tendency to focus on negative aspects of self and environment (negative affectivity) was statistically controlled. Findings indicate that gender harassment is a commonplace workplace stressor that warrants serious attention. (PsycINFO Database Record (c) 2010 APA, all rights reserved)  相似文献   
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Brodie  Mark  DeJong  Gerald 《Machine Learning》2001,45(1):45-76
We advance a knowledge-based learning method that allows prior domain knowledge to be effectively utilized by machine learning systems. The domain knowledge is incorporated not into the learning algorithm itself but instead affects only the training data. The domain knowledge is used to explain and then transform the actual training examples into a more informative set of imaginary, or phantom examples. These phantom examples are added to the training set; the experienced examples are discarded. A new control policy is induced from the phantom training set. This policy is then exercised, yielding additional training points, and the process repeats.We investigate the performance of this method in a stylized air-hockey domain which demands a difficult nonlinear control policy. Our experiments show that, surprisingly, an accurate policy can be learned even if the domain theory is only imprecise and approximate. We advance an interpretation which indicates that the information available from a plausible qualitative domain theory is sufficient for robust successful learning. This interpretation is used to make a number of predictions which are tested in subsequent experiments. The outcomes confirm the interpretation and the robustness of the approach.  相似文献   
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Using Volume Delivery Time to Identify Independent Partial Series Events   总被引:1,自引:1,他引:0  
In practice, the annual series of streamflow peaks is generally preferred than the partial series for flood frequency analysis. Flood selection criteria for the partial series tend to be arbitrary and are limited in making allowances for catchment scale. This aspect appears to be a constraint to greater acceptance of the partial series approach. The aim of this paper is to define a scalable selection criterion that reduces ambiguity in flood selection by defining floods that exceed the daily average. An approach based on the volume delivery time (VDT), analogous to the tip interval time in tipping bucket raingauges, is described and tested for three rural catchments of various sizes in South East Queensland, Australia. The VDT approach produced discharge quantile estimates similar to the partial series based on the commonly-used monthly maxima except for minor, high frequency discharges at the small, more perennial catchment. A simplified approach based on average daily volume gave similar results to the VDT method.  相似文献   
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