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A disease transmission model of susceptible-infective-recovered type with a constant latent period is analysed. The global dynamics of the disease-free equilibrium is investigated. If the basic reproduction number is greater than unity, a unique endemic equilibrium exists. Using Lyapunov functional approach, this endemic equilibrium is globally stable in the feasible region. The disease will persist (and is permanent) at the endemic equilibrium if it is initially present. The effects of loss of immunity on the dynamics of the model are analysed, and the parameters that drive the disease dynamics are obtained. Numerical simulations support our analytical results and illustrate possible behavioural scenarios of the model.  相似文献   
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