Polystyrene‐supported polyoxyethylene bound potassium permanganate as a heterogeneous oxidizing agent

Oxidation behavior of a 2 mol % divinylbenzene (DVB)‐crosslinked polystyrene‐supported permanganate function was investigated toward low molecular weight primary and secondary alcohols and aldehydes. The permanganate function was attached to a polystyrene support through cyclic polyoxyethylene (POE) units immobilized on the support. Contrary to the oxidations catalyzed by low molecular weight permanganate reagents, the oxidation of primary alcohol terminated in the aldehyde stage. The secondary alcohols were converted to the respective ketone and aldehyde to acid. The effect of the variable parameters similar to solvent, temperature, and reagent to substrate ratio was followed. Nonpolar cyclohexane was found to be the best solvent for the present study. Also the reactivity increased with increasing temperature. The oxidizing reagent possesses a long shelf life and could be recycled several times without reduction of capacity and mechanical stability. © 2003 Wiley Periodicals, Inc. J Appl Polym Sci 90: 3708–3717, 2003     

Oxygenation in the rabbit myocardium: assessment with susceptibility-dependent MR imaging

PURPOSE: To determine the feasibility of using hemoglobin (Hb) desaturation as an indicator of myocardial oxygenation. MATERIALS AND METHODS: High-resolution gradient-echo nuclear magnetic resonance (MR) images of isolated, blood-perfused rabbit hearts were obtained at various blood oxygenation levels. The hearts were perfused at 37 degrees C with a Langendorff apparatus modified for nuclear MR imaging. The perfusate contained bovine red blood cells in a cardioplegic solution that eliminated motion artifacts and minimized arteriovenous oxygenation differences. Hb saturation was varied (7%-100%) randomly. Perfusion pressure was continuously monitored, and blood samples were obtained. RESULTS: There was a substantial correlation between image signal intensity in the myocardium and Hb saturation in the blood, believed to be due to susceptibility effects of the paramagnetic species deoxyhemoglobin. CONCLUSION: Direct and noninvasive determination of regional Hb saturation with susceptibility-dependent MR imaging may provide information regarding regional myocardial O2 content.     

Development of technologies aiding large-tissue engineering

Apoptosis associated oligonucleosomal fragmentation of DNA can result from the activation of endonucleases that exhibit different pH optima and are either sensitive or insensitive to divalent cations. DNA fragmentation due to activation of cation sensitive endonucleases occurs in the absence of a change in intracellular pH whereas intracellular acidification is a feature of apoptosis characterized by activation of cation insensitive acidic endonuclease. We have reported earlier that somatostatin (SST) induced DNA fragmentation and apoptosis is signaled in a receptor subtype selective manner uniquely via human somatostatin receptor subtype 3 (hSSTR3). In the present study we investigated the pH dependence and cation sensitivity of endonuclease induced in hSSTR3 expressing CHO-K1 cells by the SST agonist octreotide (OCT) and its effect on intracellular pH. We show that OCT induced apoptosis is associated with selective stimulation of a divalent cation insensitive acidic endonuclease. The intracellular pH of of cells undergoing OCT induced apoptosis was 0.9 pH units lower than that of control cells. The effect of OCT on endonuclease and pH was inhibited by orthovanadate as well as by pretreatment with pertussis toxin, suggesting that hSSTR3 initiated cytotoxic signaling is protein tyrosine phosphatase mediated and is G protein dependent. These findings suggest that intracellular acidification and activation of acidic endonuclease mediate wild type p53 associated apoptosis signaled by hormones acting via G protein coupled receptors.     

Tensile properties of CaCO3-filled polyethylenes

Tensile stress–strain behavior and dilatation behavior of CaCO₃-filled linear polyethylenes with differing molecular weight was found to be dependent upon filler content, polymer filler interface, and polymer molecular weight. Electron microscopy of samples undergoing deformation revealed the presence of craze type deformation.     

Water quality assessment of a tropical coastal lake system using multivariate cluster,principal component and factor analysis

Statistical techniques represent a reliable tool for classifying, modelling and interpreting surface water quality monitoring data, particularly for lakes. The complexity associated with the analysis of a large number of measured variables, however, is a major problem in water quality assessments. Multivariate analysis, such as cluster analysis and factor analysis (FA), was utilized in this study for the analysis of water quality data (including water discharges and 28 water quality parameters) for Akkulam–Veli Lake, a tropical coastal lake system in Kerala, India. This lake is partially divided into two sub‐systems, namely Veli Lake and Akkulam Lake. Akkulam Lake exhibits freshwater characteristics, in contrast to Veli Lake, which exhibits saline water characteristics because of its close proximity to the sea. Thus, studying this lake provides insights into water quality variations in both a freshwater and saline water lake in a tropical region. Water quality patterns and variations in Akkulam–Vela Lake over three seasons, including pre‐monsoon (PRM), monsoon (MON) and post‐monsoon (POM), also were studied, utilizing multivariate techniques. The organic pollution factor played a significant role on lake water quality during PRM. The influence of organic pollution tends to decrease during MON and POM, a particular situation faced by urban lakes in tropical regions. Polluted stretches in a lake system during different seasons can easily be ascertained by hierarchical cluster analysis. Further, the factors affecting a lake system as a whole, as well as for a particular sampling site, can easily be identified by FA. Improved water quality can be observed during POM. Akkulam and Vela lakes exhibit a wide variation in water quality during all seasons, a finding that corroborates a water flow obstruction from Akkulam Lake to Veli Lake because of the bund existing between the two lakes. The location of the bund is identified as the major reason for different hydrochemical processes in A–V Lake.     

Geothermal energy in Australia

Although Australia is not usually associated with geothermal energy, it possesses significant amounts of both conventional (wet) geothermal and hot dry rock (HDR) geothermal resources. The country's conventional geothermal resources are extensive, but are low temperature and are located in areas of low population density with the result that they are not used extensively for either electricity generation or for direct heating. Australia's HDR resources, on the other hand, represent a world-class resource but have not been used to date because the technology for converting HDR resources into electricity is not yet fully commercial. The effort being directed towards exploring economically useful HDR resources and in the development of technology to convert this energy resource into electricity could make HDR resources an important part of Australia's energy mix in the near future, but there are major barriers.     

Hydro,tidal and wave energy in Australia

The three renewable energy technologies discussed in this paper are based on water, but differ markedly in terms of the size of the available potential resource, the maturity of the associated conversion technologies, the extent to which they have been exploited to date, and the current research effort being devoted to their future development. Hydro-electricity and tidal power are both very mature technologies. The exploitation of Australia's relatively limited potential for hydro-electric development began over a century ago and the opportunities for further hydro-electric development are now very restricted. The country's significant tidal power resources, on the other hand, have not been exploited for electricity generation to date, but continual assessment of the feasibility of tidal power projects has been undertaken over the past half century. Although Australia has large ocean wave energy resources, ocean wave energy conversion technology is not yet fully commercial and no commercial wave generation plants are operating in Australia. A small number of wave energy conversion devices, however, are at the pilot testing stage.