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排序方式: 共有2073条查询结果,搜索用时 15 毫秒
1.
Alexandra Kodadová Zuzana Vitková Petra Herdová Anton Ťažký Jarmila Oremusová Daniel Grančai 《Drug development and industrial pharmacy》2015,41(7):1080-1088
This study deals with the formulation of natural drugs into hydrogels. For the first time, compounds from the sage essential oil were formulated into chitosan hydrogels. A sample preparation procedure for hydrophobic volatile analytes present in a hydrophilic water matrix along with an analytical method based on the gas chromatography coupled with the mass spectrometry (GC-MS) was developed and applied for the evaluation of the identity and quantity of essential oil components in the hydrogels and saline samples. The experimental results revealed that the chitosan hydrogels are suitable for the formulation of sage essential oil. The monoterpene release can be effectively controlled by both chitosan and caffeine concentration in the hydrogels. Permeation experiment, based on a hydrogel with the optimized composition [3.5% (w/w) sage essential oil, 2.0% (w/w) caffeine, 2.5% (w/w) chitosan and 0.1% (w/w) Tween-80] in donor compartment, saline solution in acceptor compartment, and semi-permeable cellophane membrane, demonstrated the useful permeation selectivity. Here, (according to lipophilicity) an enhanced permeation of the bicyclic monoterpenes with antiflogistic and antiseptic properties (eucalyptol, camphor and borneol) and, at the same time, suppressed permeation of toxic thujone (not exceeding its permitted applicable concentration) was observed. These properties highlight the pharmaceutical importance of the developed chitosan hydrogel formulating sage essential oil in the dermal applications. 相似文献
2.
Annika Jahn Anton Hoffmann Luisa Blaesing Fabian Kunde Martin Bertau Martina Bremer Steffen Fischer 《化学,工程师,技术》2020,92(11):1733-1740
The enzymatic conversion of lignins, possibly in combination with electrochemical oxidation, makes aromatics such as syringol, guaiacol, vanillin and catechol available in the qualities required by the fragrance industry. The lignins were obtained by soda digestion from wheat straw and Miscanthus, characterized and then converted with laccases. The overall yield amounted up to 9 wt % with a product spectrum confined to four substances. Catechol was the major product, with a fraction of ≈75 %. It can easily be isolated by extraction with acetone. 相似文献
3.
4.
Spatial collaboration is an everyday activity in which people work together to solve a spatial problem. For example, a group of people will often arrange furniture together or exchange directions with one another. Collaborative virtual environments using desktop PCs are particularly useful for spatial activities when the participants are distributed. This work investigates ways to enhance distributed, collaborative spatial activities. This paper explores how different frames of reference affect spatial collaboration. Specifically, it reports on an experiment that examines different combinations of exocentric and egocentric frames of reference with two users. Tasks involve manipulating an object, where one participant knows the objective (director) and the other performs the interactions (actor). It discusses the advantages and disadvantages of the different combinations for a spatial collaboration task. Findings from this study demonstrate that frames of reference affect collaboration in a variety of ways and simple exocentric-egocentric combinations do not always provide the most usable solution. 相似文献
5.
移动WiMAX的发展现状 总被引:1,自引:0,他引:1
基于IEEE 802.16-2004及ETSI HiperMAN空中接口标准的WiMAX,正在被证明是一个高性价比的替代有线和DSL服务的固定无线技术.150多次的WiMAX试验及在五大洲的部署,清楚地证明了世界范围内对WiMAX作为固定无线服务技术的接受程度. 相似文献
6.
Anton Demirev 《臭氧:科学与工程》2005,27(6):475-485
The ozonation of two differently substituted azo dyes (Schwarz GRS and Orange Acid 8) in water media is studied. The influence of pH on the effectiveness of the ozonation at various initial concentrations of each dye is explored. It was found out that the rates of decolorization for amino-group substituted dyes reflect the considerable influence by the widely varying initial pH from 4.5 to 10. Specifically, the highest effect of decolorization of this dye was obtained at the highest pH studied (pH 10) for all initial concentrations of the solutions. Considering the dye without an amino-group substitute, the rates of color disappearance in ozonation reflected to a lower degree the variations of the initial pH. Pseudo-first-order trends of decolorization were observed in all the experimental runs. Regarding the kinetic results obtained, an attempt to explain the different dyes reactivity was made based on the absolute electronegativity (Elumo + Ehomo) of both dyes. The COD/BOD analysis shows that the ozonation of both azo dyes can reduce the sample COD but it could not improve the biodegradability ratio (BOD5/COD). BOD decrease with ozonation time indicates that the intermediates of the ozonation are of lower biodegradability. Oxalic acid was found as the final product of ozonation of both dyes. 相似文献
7.
Petar Liovic Murray Rudman Jong-Leng Liow Djamel Lakehal Doug Kothe 《Computers & Fluids》2006,35(10):1011-1032
A new volume tracking method is introduced for tracking interfaces in three-dimensional (3D) geometries partitioned with orthogonal hexahedra. The method approximates interface geometries as piecewise planar, and advects volumes in a single unsplit step using fully multidimensional fluxes that have their definition based in backward-trajectory remapping. By using multidimensional unsplit advection, the expense of high-order interface reconstruction is incurred only once per timestep. Simple departures from strict backward-trajectory remapping remove any need for consideration of volume computations involving shapes consisting of non-planar ruled surfaces. Second-order accuracy of the method is demonstrated even for vigorous 3D deformations. 相似文献
8.
We discuss some different ideas about the sort of formalism appropriate for translation (more specifically, transfer) that have been explored within Eurotra. The intention is not to evaluate these different ideas, but to outline the issues of general interest and relevance that they raise. Section 1 describes some common assumptions, section 2 describes the different ways they have been interpreted, and section 3 considers some further implications. 相似文献
9.
Annie I. Anton Julia B. Eart Matthew W. Vail Neha Jain Carrie M. Gheen Jack M. Frink 《Security & Privacy, IEEE》2007,5(1):45-52
Healthcare institutions typically post their privacy practices online as privacy policy documents. We conducted a longitudinal study that examines the effects of HIPAA's enactment on a collection of privacy policy documents for a fixed set of organizations over a four-year period. We present our analysis of 24 healthcare privacy policy documents from nine healthcare Web sites, analyzed using goal mining, a content-analysis method that supports extraction of useful information about institutions' privacy practices from documents. We compare our results to our pre-HIPAA study of these same institutions' online privacy practices and evaluate their evolution in the presence of privacy laws 相似文献
10.
Anton Apriyantono Jennifer M Ames 《Journal of the science of food and agriculture》1993,61(4):477-484
Aqueous molal solutions of xylose and lysine (initial pH 4–9) were refluxed either with control of the pH at 5–0 or without pH control (final pH 2–6). Analysis by gas chromatography (GC) and GC-mass spectrometry resulted in the identification of 58 and 28 compounds, respectively, from the two systems. Furans were the main reaction products in both systems and 2-furfural alone comprised 522 and 999 g kg?1 of the volatiles, respectively, from the systems with final pH values of 5–0 and 2–6. Maintaining the pH at 5–0 resulted in a higher yield and greater numbers of nitrogen-containing compounds, and monocyclic pyrroles, pyridines and 2,3-dihydro-l H-pyrrolizines were identified only in that system. Aliphatic compounds, alicyclic compounds, benzene derivatives. l-(2–furfuryl)pyrroles and pyrazines were also identified. This investigation is the first report of the formation of 2.3-dihydro-l H-pyrrolizines in a model system containing lysine as the amino compound; a possible mechanism is proposed. 相似文献