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1.
Abstract. This article proposes an extension to scalar component methodology for the identification and estimation of VARMA models. The complete methodology determines the exact positions of all free parameters in any VARMA model with a predetermined embedded scalar component structure. This leads to an exactly identified system of equations that is estimated using full information maximum likelihood.  相似文献   
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Conventional hepatitis B vaccine contains alum but is less effective to induce Th1 response. Selenium nanoparticles and Bacillus Calmette–Guerin were reported as immune modulators. In this study, SeNPs were extracted from Mycobacterium bovis and characterised. SeNPs were mixed with HBs‐Ag and administered to the mice to investigate he immune response pattern. With an addition of Se ions at a sub‐inhibitory concentration to the Sauton medium broth after 24 h, SeNPs were extracted from M. bovis and characterised by Fourier transform infrared spectroscopy, dynamic light scattering, atomic forcemicroscopy, energy dispersive X‐ray spectrum, transmission electron microscopy, and thermogravimetric analysis. Furthermore, female inbred BALB/c mice were injected subcutaneously on the first, 14th, 28th day with 100 and 200 µg doses of that SeNPs supplemented with HBs‐Ag vaccine. Later, the total antibody, isotypes of Immunoglobulin G1, Interlukin 4, and interferon‐γ were measured by enzye‐linked immunosorbent assay. The size of the SeNPs was <150 nm. Level of total antibody and immunoglobulin G2a increased significantly in the group that received 200 µg/ml nano selenium extracted from M. bovis. SeNPs in dose of 200 µg coated with organic materials of M. bovis could induce an influential immune response in relation to the conventional HBs‐Ag vaccine.Inspec keywords: selenium, nanoparticles, nanofabrication, microorganisms, Fourier transform spectra, infrared spectra, light scattering, atomic force microscopy, X‐ray chemical analysis, transmission electron microscopy, thermal analysis, nanomedicineOther keywords: biosynthesis, selenium nanoparticles, Mycobacterium bovis, enhnced immune response, HBs antigens, Bacillus Calmette‐Guerin, immune modulators, biogenic SeNPs, immune response pattern, Sauton medium broth, Fourier transform infrared spectroscopy, dynamic light scattering, atomic force microscopy, energy dispersive X‐ray spectrum, transmission electron microscopy, thermogravimetric analysis, female inbred BALB/c mice, antibody, IgG1 isotype, IgG2a isotype, IL4 isotype, interferon‐γ, enzyme‐linked immunosorbent assay, bacterium, time 24 h, time 14 day, time 28 day, Se  相似文献   
3.
In this paper, we introduce a new adaptive controller design scheme for nonlinear telerobotic systems with varying time delays where the delays and their variation rates are unknown. The designed controller has the ability to synchronize the state behaviors of the local and the remote robots. In this paper, asymptotic stability in the presence of varying time delays is of interest. Using the proposed controller, asymptotic stability of the bilateral telerobotic system subject to any bounded yet unknown varying delay with a bounded yet unknown rate of change can be guaranteed. Besides the varying time delay, the proposed adaptive controller has the ability to adapt to the parameter variations in the local and the remote robots’ dynamics. It is shown that position and velocity errors between the local and the remote manipulators converge to the zero asymptotically, thus ensuring teleoperation transparency. Experimental and simulation results with a pair of PHANToM haptic devices and a pair of planar manipulators under varying time delays in the communication channel demonstrate the effectiveness of the proposed scheme.  相似文献   
4.
In a competitive electricity market, the forecasting of energy prices is an important activity for all the market participants either for developing bidding strategies or for making investment decisions. In this paper, a new forecast strategy is proposed for day ahead prediction of electricity price, which is a complex signal with nonlinear, volatile and time dependent behavior. Our forecast strategy includes a new two stage feature selection algorithm, a composite neural network (CNN) and a few auxiliary predictors. The feature selection algorithm has two filtering stages to remove irrelevant and redundant candidate inputs, respectively. This algorithm is based on mutual information (MI) criterion and selects the input variables of the CNN among a large set of candidate inputs. The CNN is composed of a few neural networks (NN) with a new data flow among its building blocks. The CNN is the forecast engine of the proposed strategy. A kind of cross-validation technique is also presented to fine-tune the adjustable parameters of the feature selection algorithm and CNN. Moreover, the proposed price forecast strategy is equipped with a few auxiliary predictors to enrich the candidate set of inputs of the forecast engine. The whole proposed strategy is examined on the PJM, Spanish and Californian electricity markets and compared with some of the most recent price forecast methods.  相似文献   
5.
Reverse logistics consists of all operations related to the reuse of products. External suppliers are one of the important members of reverse logistics and closed loop supply chain (CLSC) networks. However in CLSC network configuration models, suppliers are assessed based on purchasing cost and other factors such as on-time delivery are ignored. In this research, a general closed loop supply chain network is examined that includes manufacturer, disassembly, refurbishing, and disposal sites. Meanwhile, it is managed by the manufacturer. We propose an integrated model which has two phases. In the first phase, a framework for supplier selection criteria in RL is proposed. Besides, a fuzzy method is designed to evaluate suppliers based on qualitative criteria. The output of this stage is the weight of each supplier according to each part. In the second phase, we propose a multi objective mixed-integer linear programming model to determine which suppliers and refurbishing sites should be selected (strategic decisions), and find out the optimal number of parts and products in CLSC network (tactical decisions). The objective functions maximize profit and weights of suppliers, and one of them minimizes defect rates. To our knowledge, this model is the first effort to consider supplier selection, order allocation, and CLSC network configuration, simultaneously. The mathematical programming model is validated through numerical analysis.  相似文献   
6.
By considering the problems that commercial saffron companies have faced in international markets, the aim of this study is to investigate the impact of website content, including informational and design dimensions, on the effectiveness of e-marketing and e-trust as mediator variables. These aspects are examined with reference to sales and marketing division managers in a sample of 100 commercial saffron corporations in the Khorasan province. The findings support the ideas that website content has an effect on e-marketing and e-trust and that e-trust plays a mediating role in the relationship between e-trust and e-marketing effectiveness.  相似文献   
7.
In the era of internet, universities and higher education institutions are increasingly tend to provide e-learning. For suitable planning and more enjoying the benefits of this educational approach, a model for measuring success of e-learning systems is essential. So in this paper, we try to survey and present a model for measuring success of e-learning systems in universities. For this purpose, at first, according to literature review, a conceptual model was designed. Then, based on opinions of 33 experts, and assessing their suggestions, research indicators were finalized. After that, to examine the relationships between components and finalize the proposed model, a case study was done in 5 universities: Amir Kabir University, Tehran University, Shahid Beheshti University, Iran University of Science & Technology and Khaje Nasir Toosi University of Technology. Finally, by analyzing questionnaires completed by 369 instructors, students and alumni, which were e-learning systems user, the final model (MELSS Model1).  相似文献   
8.
We have investigated the contact between a metal and an organic/polymeric (o/p) material and we have introduced a relation for carrier injection using Bardeen theory. A series of narrow barriers is considered in the semiconductor side to account for the localized nature of the carriers in the o/p material. As an application of the model, we have calculated the hopping rate of carriers in terms of the contact parameters. Also, we have discussed the hopping of carriers deep into the organic dielectric. Finally, we have explored the hopping rate in practical contacts between polyfluorene-based polymers and different electrodes.  相似文献   
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