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1.
The Wendelstein 7-X (W7-X) modular stellarator is in the assembly phase at the Max-Planck-Institut für Plasmaphysik in Greifswald, Germany. The design of the “basic machine”, i.e. without in-vessel components, diagnostics and periphery, is largely completed, structural parameters such as bolt preload, initial conditions for contact elements, etc. are defined, and most of the components are manufactured and partly assembled. Therefore, the focus of structural analysis was shifted towards fast analyses of non-conformities, changes in the assembly procedure, and exploration of operational limits. Assembly-related work is expected to continue until commissioning of the machine, however, with decreasing intensity. In parallel the analysis requirements for in-vessel components, diagnostics and periphery will increase.This paper focuses on the most remarkable results, on special problems which had to be solved, on strategic issues like parameterization, complex finite element model structuring and benchmarking with alternative models in different codes, on assumptions of reasonable safety margins and expected tolerances, and on confirmation of analysis results by tests. Finally it highlights some lessons learned so far, which might be relevant also for other large fusion machines, and gives an outlook on future work.  相似文献   
2.
The time course of the vinblastine(-sulfate; 10 mg/kg body weight, single injection)-induced enlargement and subsequent regression of the autolysosomal compartment was studied by electron microscopic morphometrical and cell biochemical methods in order to gain information concerning some key problems of this major route of intralysosomal degradation of the cell's endogenous macromolecules and structures. Detailed analysis of the dynamics of the total autophagic vacuole (AV) compartment and its different subcompartments (early, advanced, late, and fused AVs), as well as of changes of rough-surfaced endoplasmic reticulum (RER) showed: 1. Pancreatic acinar cells react to vinblastine biphasically, i.e. two expansion phases of the AV compartment, the first in the 0 to 90 min and the second in the 2 to 8 h post-injectional periods, were detected. 2. Fusions of AVs are not inhibited by vinblastine, at least during the second expansion phase when cytoplasmic volume fraction (CVF) of fused AVs steadily increased until the 12th h. Fusion of early, advanced and late AVs or composition of fused complex vacuoles (AVc) are somehow regulated, as the proportion of the three AV stages from the CVF of AVc, was maintained constant throughout the second expansion phase. 3. Stimulation of autophagosome formation and resulting substrate overload seems to be the primary mode of action by which vinblastine causes the enormous expansion of the autolysosomal compartment. 4. Degranulation of the rough-surfaced endoplasmic reticulum (RER) membranes occurs in a biphasic fashion, similarly to the volume and surface changes of the AV compartment, thus supporting our previous hypothesis, that labilization or change of RER may have a role in the formation of autophagosomes. 5. Vinblastine-induced autophagocytosis is a selective process, as mitochondria, Golgi elements and zymogen granules are very much underrepresented, whereas RER is more than twice overrepresented in the volume of early AVs, when compared to their volume fraction in the whole cytoplasm. 6. Immunogold electron microscopy revealed the presence of ubiquitinylated proteins in advanced and late, but not in early AVs.  相似文献   
3.
Detectors based on optically stimulated luminescence are useful for fast neutron dosimetry. For this one needs the neutron sensitivity of these detectors. We describe a procedure for the calculation of the neutron sensitivity. For CaF2:Mn embedded in polyethylene the calculated values are compared with experimentally determined neutron sensitivities. There is good agreement.  相似文献   
4.
In a previous paper we presented the calculation procedure of the neutron senstivity of radiator-TL detector combinations. For checking the general validity of the calculation method, measurements are required. The results for CaSO4:Dy, CaF2:Mn and 7LiF combined with polyethylene radiators are in good agreement with the calculated values.  相似文献   
5.
Simulation of the fatigue crack propagation in a Wendelstein 7‐X baffle module is performed in this study using both a finite element method‐based software and the UniGrow nonlinear model for small‐scale yielding (SSY) conditions. Some experimental fatigue tests of several cracked baffle modules have been performed through a servo‐hydraulic machine. One of these experimental tests has been considered to simulate fatigue crack propagation in the baffle module. Before starting the experimental test, a first crack partly contained in the welding seam and partly in the steel pipe is found. Subsequently, owing to the applied load, the crack propagated both into the welding seam and into the steel pipe until the plastic zone in the near field attains SSY conditions. Finally, owing to the increase in the extension of the plastic zone, SSY conditions are not more valid, and the breakage of the steel pipe is produced by plastic collapse.  相似文献   
6.
From 1986 to 1991 we fitted 20 children with endoprostheses after resection of malignant bone tumours of the leg; six have reached skeletal maturity and are the subject of this study. Reconstruction of defects in growing limbs in which the eventual shortening can be predicted requires the use of extendable prostheses. The mean age at operation was 11 years (9.2 to 13.7) and the average follow-up period was 6.3 years (4.3 to 7.6). The diagnosis was osteosarcoma in five patients and Ewing's sarcoma in one. All tumours were Enneking stage-IIB. When seen for follow-up all patients were free from disease. The extendable implants used included the Pafford-Lewis prosthesis and the Kotz Modular Femur Tibia Reconstruction system with a compatible, newly-designed growth module. Telescope-like elongation of the prostheses was performed by insertion of a screwdriver through a small skin incision. Active epiphyseal growth in the adjacent growth plate was preserved by using prosthetic stems with a smooth surface. The mean length gained was 13.15 cm (4.5 to 19.5) requiring 53 planned procedures. Seven revision operations were necessary for complications. Functional evaluation showed excellent and good results in all cases. Stress-shielding at the site of anchorage of the prosthesis was more pronounced than in adults. Implantation of extendable endoprostheses in children provides a reasonable alternative to rotationplasty, but limb salvage requires more operations.  相似文献   
7.
The elastic wave field of certain angle beam probes used for nondestructive testing of solid materials, like steel, has been shown to exhibit a so-called subsurface longitudinal wave, i.e., a wavefront traveling with the pressure wave speed having a beam angle of approximate 74° in steel. In addition, this wavefront is supposed to be connected to the stress-free surface via a headwave, which radiates a nearly plane wave with shear velocity into the bulk material under an angle of 33°, approximately, and giving rise to a strongly attenuated longitudinal creeping wave on the surface. In the present paper we utilize a new numerical scheme for the computation of elastodynamic wave fields in nearly arbitrary environments, called elastodynamic finite integration technique (EFIT), to predict the above-mentioned wave features quantitatively. Furthermore, we employ several analytical and analytical-numerical integration procedures to evaluate the angle beam probe plane wave spectrum in terms of an inverse spatial Fourier transform. This gives rise to a theoretical interpretation of the physical origin of the numerically computed EFIT wavefronts. Essential results are as follows: the particular wavefronts of angle beam probes, as referred to in this paper, are exclusively associated with afinite aperture radiating into an elastic half-space; they cannot be explained in terms ofsingle homogeneous and inhomogeneousplane waves. The subsurface longitudinal wave emerges from the superposition of the edge pressure waves of the transducer, resulting in a propagation with pressure wave speed, but, in the near-field, where it is often employed, it is not longitudinally polarized. On the surface, and very close to it, the superposition of the subsurface longitudinal wave and the head waves associated with the probe edges gives rise to a strongly attenuated wavefront exhibiting longitudinal as well as transverse particle displacement components, but neither a surface wave nor a creeping wave is really involved. The bulk shear wavefront is not an appendix of the head wave but the geometric optical shear wave radiation pattern of the finite probe.This article is dedicated to Professor Dr. Paul Höller on the occasion of his 65th birthday.  相似文献   
8.
Hierarchically structured carbon aerogels are produced in a simple, rapid, efficient, and sustainable hydrothermal approach, using only glucose as the carbon precursor. Using sodium borate (borax) as a novel complex structure directing agent nanostructured, carbon monoliths, structurally similar to the well‐known sol‐gel monoliths made of silica are obtained. Experimental results indicate the acetalization reaction of monosaccharides with their dehydration product hydroxymethylfurfural to be very important and inhibiting in the process of hydrothermal carbonization. Addition of borax, leads to a competitive complexation of diols, resulting in promising secondary catalytic effect with regard to carbon yield. Accordingly, it is shown that the sugar:borax ratio directs the primary carbon nanoparticle size into the sub ?50 nm range, while their spinodal destabilization ultimately results in the controlled aggregation of carbonaceous particles leading to the formation of monoliths in a simple one step hydrothermal process. Post‐synthesis thermal carbonization is also used to increase surface area to the medium‐high range, introducing electric conductivity into the carbon monoliths. The resulting materials are promising candidates for applications in flash chromatography, for fast adsorption/purifications, and as porous conductive electrodes.  相似文献   
9.
At the Max Planck Institute for plasma physics in Greifswald, Germany, the world's largest nuclear fusion experiment of modular stellarator type Wendelstein 7‐X has started plasma operation. The hot hydrogen plasma is confined in a plasma vessel by an electromagnetic field generated by 50 non‐planar and 20 planar superconducting coils. The superconducting coils are encased in cast stainless steel housings. The coils are bolted onto a central support ring and welded together by so called lateral support elements (LSEs). In this paper, a procedure, based on a global–local finite element method (FEM)–dual boundary element method (DBEM) approach, is developed to simulate the propagation of multiple cracks detected in LSEs and undergoing a fatigue load spectrum. The global stress analysis on the superconducting coils is performed by FEM whereas the sub‐modelling approach is adopted to solve the crack propagation in the DBEM environment. The boundary conditions applied on the DBEM submodel are the displacements calculated by the FEM global analysis, in correspondence of the cut surfaces (there are no body forces nor external loads applied on the submodel volume). Two cracks are simultaneously introduced, and a linear elastic fracture mechanics analysis is performed. Results in terms of cracks growth rates and evolving crack shapes are provided, and the residual life of the component is forecast.  相似文献   
10.
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