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This study was performed in order to clarify crack opening displacement (COD) of through-wall cracks in a plate subjected to bending load. The former COD evaluation methods were mainly developed corresponding to tensile load, but there has been nothing that has been developed corresponding to bending load. Therefore, the authors evaluated CODs of the through-wall cracks in plates which were subjected to a bending load using finite element method (FEM) analyses, and proposed a simplified COD evaluation method accounting for both tensile and bending loads. The proposed method is useful for leakage evaluation at a crack opening of an elbow crown or in the vicinity of the coolant surface of a vessel in which the bending stress is relatively large.  相似文献   
3.
The c-kit protooncogene encodes a receptor tyrosine kinase that mediates signals required for differentiation, proliferation and survival of mast cells. We have already shown the constitutive activation of c-kit receptor tyrosine kinase (KIT) in a human mast cell leukemia line (HMC-1) and a murine mastocytoma cell line (P-815). We here examined whether such constitutive activation of KIT occurred in the rat tumor mast cell line RBL-2H3 as well, which is frequently used as a tool for studying functions of mast cells. In RBL-2H3 cells, KIT was constitutively phosphorylated on tyrosine and activated in the absence of autocrine production of its ligand, stem cell factor (SCF). Sequencing analysis revealed that one of c-kit genes of RBL-2H3 cells had a point mutation, resulting in amino acid substitution of Tyr for Asp in codon 817. When rat wild-type c-kit cDNA and mutant-type c-kit cDNA encoding KITTyr817 were transfected into cells of a human embryonic kidney cell line (293T), only mutant form KITTyr817 was constitutively phosphorylated on tyrosine and activated in the absence of SCF. Since mutations at the same Asp codon constitutively activated KIT in all the human HMC-1, murine P-815, and rat RBL-2H3 cell lines, and since the incorporation of antisense oligonucleotides of c-kit messenger RNA significantly suppressed the proliferation of RBL-2H3 cells, the activating mutations in the Asp codon of the c-kit gene appeared to be involved in neoplastic growth of mast cells.  相似文献   
4.
Brushless three-phase synchronous motor involving a rotating ac exciter on the same shaft as the motor and with the windings linked through a shaft-mounted rectifier is widely used as medium and large capacity machines. However, the motor needs to fit with damping windings for self-starting outside of the field winding in the rotor and needs to equip discharge resistance with complex electronic device to dispose of electromagnetic force induced in the field winding at starting. Therefore, the rotor structure is very complex, and there are disadvantages, especially for the robust and highly reliable motor that is desired. To solve the problem found in traditional motors, the authors proposed a brushless three-phase synchronous induction motor with two stators and one wound rotor. This problem is solved because the proposed motor is of two-stators structure: the rotor winding operates as a secondary winding of induction motor at starting and as the field winding at synchronous operation. The motor can self-start as a wound-rotor induction motor without external secondary resistance. Therefore, discharge resistance is not necessary; the starting equipment is very simple and the rotor structure is robust. It is possible to start with high torque. In this paper, the basic constitution of the proposed motor and the principles of operation are described in detail. The experimental results at starting and pulling into synchronism are shown for confirming the principles of operation and the experimental and numerical results of the starting characteristics. The load ones and the generating ones are shown and then the practical use of the proposed motor is confirmed.  相似文献   
5.
Racemic amino acid esters were optically resolved via hydrolysis in organic solvents by the catalysis of an industrial alkaline protease, “Alcalase”. The products which were composed mainly of L-amino acids were insoluble and easily separated by filtration. The activity of the enzyme and enantiomeric excess of the products were significantly dependent on the nature of solvent and the water content in the reaction media. Generally, high values of enantiomeric excess were obtained at low water contents. Many natural and unnatural amino acids were resolved by this method.  相似文献   
6.
This paper describes a numerical method for analyzing turbulent liquid metal magnetohydrodynamic flow in a rectangular duct under a transverse magnetic field. The main features of the proposed method are as follows: (1) a new iterative solution procedure is implemented to satisfy the conservation law for the electric current density; (2) Buleev's turbulence model is employed to calculate the turbulent intensities and shear stresses. The iterative solution procedure is tested and its ability is illustrated through solution of an example problem that corresponds to Hartmann's theoretical work. In order to verify the applicability of the turbulence model, the present method is applied to an analysis of Reed and Lykoudis's experimental data. The obtained numerical results agree well with the experimental data except for some slight differences.  相似文献   
7.
A second-generation model of cubicletype gas-insulated switchgear (C-GIS) with composite insulation incorporating SF6 gas has been developed. The design does not require a gas process in field assembly; it has high reliability and its installation is more rapid; and a further reduction in size is achieved. The design principles are described in detail.  相似文献   
8.
An ideal fabrication process is designed to minimize mechanical stress in semiconductor devices and to improve device reliability. Mechanical stress levels were predicted by in-house simulations supported by a thin-film database. These stress levels were correlated with stress-induced defects by TEM analysis supported by fail bit addressing on matured megabit SRAMs. Amorphous-doped silicon film with various annealing temperatures were used for the gate electrode to change the mechanical stress in devices and to get the direct relationship between predicted stress levels and stress related defects. The authors describe brief guidelines for suppressing dislocations in the small geometry shallow-trench isolation process utilizing this system. Polysilicon thickness in the W-polycide gate electrode is designed to minimize mechanical stress in the gate oxide and to suppress the gate oxide failure in probe and class tests. Moreover, critical stress generates dislocations during post source/drain ion implantation anneal obtained by a ball indentation method. This indicated that lower temperature anneal is effective in suppressing the dislocations. A two-step anneal was introduced to suppress dislocations and to enable higher ion activation.  相似文献   
9.
To present axes for evaluating the water resources, lake environment and water use in a lake and its watershed, a comparative study was done for four East Asian lakes; lake Kasumigaura (Japan), Lake Laguna (Philippines), Lake Songkhla (Thailand) and Lake Dianchi (China). Two axes were then determined from the relationship between: (1) water use and water supply rate, and (2) water use and water quality. To clarify the meanings ‘carrying capacity’ and ‘vulnerability’, the maximum population density in the lake basin and total nitrogen concentration in the lake water were calculated and discussed to decide the direction of environmentally sound management of the drainage basin.  相似文献   
10.
A nonlinear calibration curve for volume fraction vs integrated intensity ratio was obtained for the monoclinic-tetragonal ZrO2 system by using X-ray powder pattern-fitting and pattern-decomposition techniques. The empirical equation agrees well with the theoretical one. By using this equation, the deviation from linearity (6.8% maximum) resulting from the intensity difference of corresponding reflections of the two phases can be estimated quite accurately.  相似文献   
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