Serologic evidence of previous Campylobacter jejuni infection in patients with the Guillain-Barré syndrome

OBJECTIVE: To determine if patients with the Guillain-Barré syndrome are likely to have had Campylobacter jejuni infection before onset of neurologic symptoms. DESIGN: A case-control study. SETTING: Several university medical centers. PATIENTS: Case patients met clinical criteria for the Guillain-Barré syndrome between 1983 and 1990 and had a serum sample collected and frozen within 3 weeks after onset of neurologic symptoms (n = 118). Disease controls were patients with other neurologic illnesses (n = 56); healthy controls were hospital employees or healthy family members of patients (n = 47). MEASUREMENTS: Serum IgA, IgG, and IgM antibodies to C. jejuni were determined by enzyme-linked immunosorbent assays. Assays were done in a blinded manner. RESULTS: Optical density ratios > or = 2 in two or more immunoglobulin classes were seen in 43 (36%) of patients with the Guillain-Barré syndrome and in 10 (10%) of controls (odds ratio, 5.3; 95% CI, 2.4 to 12.5; P < 0.001). Increasing the optical density ratio or the number of immunoglobulin classes necessary to yield a positive result increased the strength of the association. The number of patients with the Guillain-Barré syndrome who had positive serologic responses was greatest from September to November (P = 0.02). Male patients were three times more likely to have serologic evidence of C. jejuni infection (P = 0.009); the proportion of patients with the syndrome who had a positive serologic response increased with age. CONCLUSIONS: Patients with the Guillain-Barré syndrome are more likely than controls to have serologic evidence of C. jejuni infection in the weeks before onset of neurologic symptoms. Campylobacter jejuni may play a role in the initiation of the Guillain-Barré syndrome in many patients.     

Automatic Channel Detection Using DNN on 2D Seismic Data

Geologists interpret seismic data to understand subsurface properties and subsequently to locate underground hydrocarbon resources. Channels are among the most important geological features interpreters analyze to locate petroleum reservoirs. However, manual channel picking is both time consuming and tedious. Moreover, similar to any other process dependent on human intervention, manual channel picking is error prone and inconsistent. To address these issues, automatic channel detection is both necessary and important for efficient and accurate seismic interpretation. Modern systems make use of real-time image processing techniques for different tasks. Automatic channel detection is a combination of different mathematical methods in digital image processing that can identify streaks within the images called channels that are important to the oil companies. In this paper, we propose an innovative automatic channel detection algorithm based on machine learning techniques. The new algorithm can identify channels in seismic data/images fully automatically and tremendously increases the efficiency and accuracy of the interpretation process. The algorithm uses deep neural network to train the classifier with both the channel and non-channel patches. We provide a field data example to demonstrate the performance of the new algorithm. The training phase gave a maximum accuracy of 84.6% for the classifier and it performed even better in the testing phase, giving a maximum accuracy of 90%.     

Variance sensitive adaptive threshold-based PCA method for fault detection with experimental application

Principal Component Analysis (PCA) is a statistical process monitoring technique that has been widely used in industrial applications. PCA methods for Fault Detection (FD) use data collected from a steady-state process to monitor T² and Q statistics with a fixed threshold. For the systems where transient values of the processes must be taken into account, the usage of a fixed threshold in PCA method causes false alarms and missing data that significantly compromise the reliability of the monitoring systems. In the present article, a new PCA method based on variance sensitive adaptive threshold (T_vsa) is proposed to overcome false alarms which occur in the transient states according to changing process conditions and the missing data problem. The proposed method is implemented and validated experimentally on an electromechanical system. The method is compared with the conventional monitoring methods. Experimental tests and tabulated results confirm the fact that the proposed method is applicable and effective for both the steady-state and transient operations and gives early warning to operators.     

DeepClassRooms: a deep learning based digital twin framework for on-campus class rooms

Neural Computing and Applications - A lot of different methods are being opted for improving the educational standards through monitoring of the classrooms. The developed world uses Smart...     

Coordinated controller tuning of a boiler turbine unit with new binary particle swarm optimization algorithm

Coordinated controller tuning of the boiler turbine unit is a challenging task due to the nonlinear and coupling characteristics of the system. In this paper, a new variant of binary particle swarm optimization (PSO) algorithm, called probability based binary PSO (PBPSO), is presented to tune the parameters of a coordinated controller. The simulation results show that PBPSO can effectively optimize the control parameters and achieves better control performance than those based on standard discrete binary PSO, modified binary PSO, and standard continuous PSO.     

Artificial Neural Networks for Prediction of COVID-19 in Saudi Arabia

In this study, we have proposed an artificial neural network (ANN) model to estimate and forecast the number of confirmed and recovered cases of COVID-19 in the upcoming days until September 17, 2020. The proposed model is based on the existing data (training data) published in the Saudi Arabia Coronavirus disease (COVID-19) situation—Demographics. The Prey-Predator algorithm is employed for the training. Multilayer perceptron neural network (MLPNN) is used in this study. To improve the performance of MLPNN, we determined the parameters of MLPNN using the prey-predator algorithm (PPA). The proposed model is called the MLPNN–PPA. The performance of the proposed model has been analyzed by the root mean squared error (RMSE) function, and correlation coefficient (R). Furthermore, we tested the proposed model using other existing data recorded in Saudi Arabia (testing data). It is demonstrated that the MLPNN-PPA model has the highest performance in predicting the number of infected and recovering in Saudi Arabia. The results reveal that the number of infected persons will increase in the coming days and become a minimum of 9789. The number of recoveries will be 2000 to 4000 per day.     

Flow and heat transfer of two immiscible fluids in double-layer optical fiber coating

The coatings of optical fibers are generally characterized by a multi-layer coating structure. In this work, the mathematical modeling of two immiscible non-Newtonian fluids for optical fiber coating inside a straight annular die is developed in the form of a nonlinear differential equation with nonhomogeneous boundary conditions. Two non-Newtonian fluids, namely power law and Phan-Thien–Tanner fluids, are used in the primary and secondary coating dies, respectively. An exact solution is obtained for velocity fields and temperature distributions for the primary and secondary coating resins. The thickness of coated fiber optics is also calculated for both layers. The effect of different emerging parameters on the solution is discussed and sketched.     

Molecular dynamics simulation of compressible hot/cold moving lid-driven microcavity flow

Hard-sphere molecular dynamics simulations of lid-driven microcavity gas flow with various subsonic speeds and lid temperatures are conducted. Simulations with faster and colder lids show streamlines of stronger primary vortices. Variations of mass and energy centers with respect to lid speed and temperature are examined. Center of energy is less sensitive to employed lid conditions than center of gravity is. Although moving lid imparts energy into fluid, due to change of impingement rates on the walls of fixed temperature, average energy within the cavity seems quite insensitive to the subsonic lid speed. Behavior of compressibility at both top corners is observed even at low Mach numbers widely considered within incompressible flow region. While high Knudsen number causes considerable property slips near the lid, two-dimensional pressure, density, and temperature plots of excellent quality are generated. Results are promising in use of molecular dynamics simulations for compressible vortex flow analyses while providing insights for understanding microfluidics and nanofluidics in context of molecular mass, momentum and heat transfer in microscale and nanoscale systems.     

Performance of cryogenically treated M35 HSS drills in drilling of austenitic stainless steels

In this study, performance of cryogenically treated M35 high speed steel (HSS) twist drills in drilling of AISI 304 and 316 stainless steels was evaluated in terms of thrust force, surface roughness, tool wear, tool life, and chip formation. To present the differences in tool performance between untreated and treated drills, and machinability between AISI 304 SS and AISI 316 SS, a number of experiments were performed at different combinations of cutting speed, and feed rate. As the results of the conducted experiments, the treated drills showed better performance than untreated drills in terms of thrust force, surface roughness, and tool wear and tool life for both types of stainless steels. Tool lives of treated HSS drills in drilling of AISI 304 SS and AISI 316 SS improved 32% and 14%, respectively, when compared with untreated drills. Experimental results also showed that machinability of AISI 304 SS was harder than the machinability of AISI 316 SS.