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排序方式: 共有354条查询结果,搜索用时 15 毫秒
1.
FilippoDiGiovanni GnetanoBazzano AntonioGrimaldi 《今日电子》2003,(3):40-41
功率转换器的功率密度越来越高,发热问题越来越严重,这种功率转换器的设计对现代大功率半导体技术提出了新的挑战;因而,热问题的优化设计和核实变得比大功率器件的电模型更加重要,本文提出一种新的PSPICE模型,可以利用它计算MOSFET芯片在瞬变过程中的温度。其中的热阻可以从制造商提供的产品使用说明书得到。本文介绍的模型提供发热和电气参数之间的动态关系。它建立了与许可的热环境的关系,例如,栅极驱动电路、负载、以及散热器的分析与优化设计。利用这个模型可以改善散热器的设计。由于决定功率损耗的参数是分布在一定范围内,受生产制造的影响很大,因而散热器的设计往往由于无法预先知道功率损耗而无法进行。 相似文献
2.
Baccigalupi A. Daponte P. Grimaldi D. 《IEEE transactions on instrumentation and measurement》1994,43(5):774-776
This paper provides a method for evaluating three lumped equivalent capacitances which take into account the physical effects of stray capacitances in two coupled inductors. Capacitance evaluation is performed in two steps: (i) initially, the resistance and leakage inductance of each winding, together with the magnetic core equivalent impedance, are evaluated by means of discrete parameter estimation; (ii) successively, the three equivalent capacitances are evaluated by resolving a linear set of three algebraical equations after the natural oscillation frequencies of the two coupled inductors in experimental tests are determined. The paper provides both the definitions and the mathematical theory on which the method is based. The actual response of two coupled inductors was compared with the response of the identified model; tests showed a good correlation between them 相似文献
3.
Zhao Donghui Wang Hua Chen Guorong Stefania Baccaro Angelica Cecilia Mauro Falconieri L. Pilloni 《Journal of the American Ceramic Society》2006,89(11):3582-3584
Gamma-ray irradiations induced various alterations in sulfur- and selenium-based chalcogenide glasses. The absorbed dose was in the range of 0.01–3.6 MGy. The glasses exhibit prominent sensitivity to γ-ray irradiation, characterized by changes in some of the physical properties of the glasses, e.g., optical transmission, optical band gap, density, and thermal expansion coefficient. The effects on glass structure and microscopic morphology were also studied by Raman spectra and scanning electron microscopic observations. 相似文献
4.
The neuroprotective actions of cannabidiol and other cannabinoids were examined in rat cortical neuron cultures exposed to toxic levels of the excitatory neurotransmitter glutamate. Glutamate toxicity was reduced by both cannabidiol, a nonpsychoactive constituent of marijuana, and the psychotropic cannabinoid (-)Delta9-tetrahydrocannabinol (THC). Cannabinoids protected equally well against neurotoxicity mediated by N-methyl-D-aspartate receptors, 2-amino-3-(4-butyl-3-hydroxyisoxazol-5-yl)propionic acid receptors, or kainate receptors. N-methyl-D-aspartate receptor-induced toxicity has been shown to be calcium dependent; this study demonstrates that 2-amino-3-(4-butyl-3-hydroxyisoxazol-5-yl)propionic acid/kainate receptor-type neurotoxicity is also calcium-dependent, partly mediated by voltage sensitive calcium channels. The neuroprotection observed with cannabidiol and THC was unaffected by cannabinoid receptor antagonist, indicating it to be cannabinoid receptor independent. Previous studies have shown that glutamate toxicity may be prevented by antioxidants. Cannabidiol, THC and several synthetic cannabinoids all were demonstrated to be antioxidants by cyclic voltametry. Cannabidiol and THC also were shown to prevent hydroperoxide-induced oxidative damage as well as or better than other antioxidants in a chemical (Fenton reaction) system and neuronal cultures. Cannabidiol was more protective against glutamate neurotoxicity than either ascorbate or alpha-tocopherol, indicating it to be a potent antioxidant. These data also suggest that the naturally occurring, nonpsychotropic cannabinoid, cannabidiol, may be a potentially useful therapeutic agent for the treatment of oxidative neurological disorders such as cerebral ischemia. 相似文献
5.
Roberto Lande Immacolata Pietraforte Anna Mennella Raffaella Palazzo Francesca Romana Spinelli Konstantinos Giannakakis Francesca Spadaro Mario Falchi Valeria Riccieri Katia Stefanantoni Curdin Conrad Cristiano Alessandri Fabrizio Conti Loredana Frasca 《International journal of molecular sciences》2021,22(4)
LL37 acts as T-cell/B-cell autoantigen in Systemic lupus erythematosus (SLE) and psoriatic disease. Moreover, when bound to “self” nucleic acids, LL37 acts as “danger signal,” leading to type I interferon (IFN-I)/pro-inflammatory factors production. T-cell epitopes derived from citrullinated-LL37 act as better antigens than unmodified LL37 epitopes in SLE, at least in selected HLA-backgrounds, included the SLE-associated HLA-DRB1*1501/HLA-DRB5*0101 backgrounds. Remarkably, while “fully-citrullinated” LL37 acts as better T-cell-stimulator, it loses DNA-binding ability and the associated “adjuvant-like” properties. Since LL37 undergoes a further irreversible post-translational modification, carbamylation and antibodies to carbamylated self-proteins other than LL37 are present in SLE, here we addressed the involvement of carbamylated-LL37 in autoimmunity and inflammation in SLE. We detected carbamylated-LL37 in SLE-affected tissues. Most importantly, carbamylated-LL37-specific antibodies and CD4 T-cells circulate in SLE and both correlate with disease activity. In contrast to “fully citrullinated-LL37,” “fully carbamylated-LL37” maintains both innate and adaptive immune-cells’ stimulatory abilities: in complex with DNA, carbamylated-LL37 stimulates plasmacytoid dendritic cell IFN-α production and B-cell maturation into plasma cells. Thus, we report a further example of how different post-translational modifications of a self-antigen exert complementary effects that sustain autoimmunity and inflammation, respectively. These data also show that T/B-cell responses to carbamylated-LL37 represent novel SLE disease biomarkers. 相似文献
6.
C. Tuve' R. Potenza M. Chiorboli M.G. Grimaldi F. La Rosa F. Raimondo M. Marinelli E. Milani A. Tucciarone G. Verona Rinati M. Donato G. Faggio G. Messina S. Santangelo G. Pucella 《Diamond and Related Materials》2006,15(11-12):1986
Polycrystalline (pCVD) and single crystal (scCVD) diamond films grown from Chemical Vapour Deposition (CVD), if sufficiently pure at Raman analysis, are very good materials for beam or flux monitors inside accelerators or nuclear reactors. This is because they are very hard to damage in high radiation fields and very resistant to high temperatures. Films of pCVD diamond are, however, not so good as spectroscopy detectors due to inhomogeneities induced by their growth in grains with the consequent presence of grain boundaries which worsen their energy resolution. The latter can be significantly improved by growing scCVD diamond films onto HPHT synthetic diamond substrates. We have shown that it is possible to measure the density of defects inside diamond specimens using as probes suitable penetrating nuclear radiations. With the preliminary results reported here we'll show that, bombarding CVD diamond films grown at Roma “Tor Vergata” with energetic protons and 4He, 6Li and 12C ions produced in the accelerators of Catania laboratories, the pulse height defects are higher than those in silicon detectors and likewise well described by a power law in the deposited energy. Furthermore, we'll show that pulse heights for the same particles seem to depend on the duration of the measurement, thus exhibiting a sort of depolarization of the insulator when exposed to the electric voltage which makes it a particle detector. 相似文献
7.
Linear polyethers possess unusually high CO2 solubility and, hence, selectivity due to the presence of accessible ether linkages that can interact with the quadrupolar moment of CO2 molecules. In this work, membranes derived from crosslinked poly(propylene glycol) diacrylate (PPGda) oligomers differing in molecular weight (M), as well as PPGda nanocomposites containing either an organically-modified montmorillonite clay or a methacrylate-terminated fumed silica are investigated and compared with highly CO2-selective poly(ethylene glycol) diacrylate (PEGda) homopolymer and nanocomposite membranes previously reported. The rheological and permeation properties of PPGda depend sensitively on M, with the elastic modulus decreasing, but CO2 permeability and CO2/H2 selectivity increasing, with increasing M. Incorporation of either nanofiller into PPGda enhances the elastic modulus and reduces the gas permeability in the resultant nanocomposites without strongly affecting CO2/H2 selectivity. Blending PPGda and PEGda prior to chemical crosslinking yields binary membranes that exhibit intermediate gas-transport properties accurately described by a linear rule of mixtures. 相似文献
8.
Andrea Caiti Vincenzo Calabrò Andrea Munafò Gianluca Dini Angelica Lo Duca 《野外机器人技术杂志》2013,30(2):237-253
The EU‐funded project UAN (Underwater Acoustic Network) was aimed at conceiving, developing, and testing at sea an innovative and operational concept for integrating underwater and above‐water sensors in a unique communication system to protect offshore and coastline critical infrastructures. This work gives details on the underwater part of the project. It introduces a set of original security features and gives details on the integration of autonomous underwater vehicles (AUVs) as mobile nodes of the network and as surveillance assets, acoustically controlled by the command and control center to respond against intrusions. Field results are given of the final UAN project sea trial, UAN11, held in May 2011 in Norway. During the experimental activities, a UAN composed of four fixed nodes, two AUVs, and one mobile node mounted on the supporting research vessel was operated continuously and integrated into a global protection system. In this article, the communication performance of the network is reported in terms of round‐trip time, packet loss, and average delivery ratio. The major results of the experiment can be thus summarized: the implemented network structure was successful in continuously operating over five days with nodes seamlessly entering and exiting the network; the performance of the network varied greatly with fluctuations in the acoustic channel; the addition of security features induced a minor degradation in network performance with respect to channel variation; the AUVs were successfully controlled from a remote station through acoustic signals routed by the network. © 2013 Wiley Periodicals, Inc. 相似文献
9.
We propose an experimental methodology to determine the secondary Bjerknes force between rigid particles. Measurements done for different particles sizes showed acoustical inter particles interactions. We use and extend the methodology presented in a previous work. The determination of this force will lead us a better understanding of the aggregation process in acoustic resonators. We report in this work, the results of two parabolic flights campaigns performed at the Airbus A300 ZERO-G (Novespace, France). 相似文献
10.
Garzón-Alvarado DA Martinez AM Segrera DL 《Computer methods and programs in biomedicine》2011,104(3):489-497
The cerebral cortex is a gray lamina formed by bodies of neurons covering the cerebral hemispheres, varying in thickness from 1.25 mm in the occipital lobe to 4 mm in the anterior lobe. The brain's surface is about 30 times greater that of the skull because of its many folds; such folds form the gyri, sulci and fissures and mark out areas having specific functions, divided into five lobes. Convolution formation may vary between individuals and is an important feature of brain formation; such patterns can be mathematically represented as Turing patterns. This article describes how a phenomenological model was developed by describing the formation pattern for the gyri occurring in the cerebral cortex by reaction diffusion equations with Turing space parameters. Numerical examples for simplified geometries of a brain were solved to study pattern formation. The finite element method was used for the numerical solution, in conjunction with the Newton–Raphson method. The numerical examples showed that the model can represent cerebral cortex fold formation and reproduce pathologies related to gyri formation, such as polymicrogyria and lissencephaly. 相似文献