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1.
V. A. Grechishnikov Yu. E. Petukhov P. M. Pivkin A. V. Isaev V. B. Romanov V. A. Kosarev A. S. Babaev A. A. Ershov 《Russian Engineering Research》2020,40(1):70-72
The shaping of the toroidal cutting section of end mills is considered. Methods are devised for selecting the positional parameters in shaping the helical rake surface on the toroidal section. Relations are established between the geometric parameters of the end mill in the toroidal section. 相似文献
2.
A. D. Bulanov A. N. Moiseev O. Yu. Troshin V. V. Balabanov D. V. Isaev 《Inorganic Materials》2004,40(6):555-557
High-purity isotopically enriched (99.98% 28Si, 99.57% 29Si, and 99.83% 30Si) silane samples are prepared for the first time. The total hydrocarbon content of the samples is no higher than 0.1–0.3 ppm. The concentration of electroactive impurities in the silicon prepared from the purified monoisotopic silane is below 1015 cm–3. 相似文献
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S. A. Isaev V. B. Kharchenko Ya. P. Chudnovskii 《Journal of Engineering Physics and Thermophysics》1994,67(5-6):1013-1017
A three-dimensional flow in the neighborhood of a shallow well on a plane was simulated numerically on the basis of a solution of the Reynolds equations written in curvilinear nonorthogonal coordinates and closed by a two-parametric dissipative model of turbulence.The work has been financed by the Russian Basic Research Foundation (Grant No. 94-02-04092 a).Civil Aviation Academy, St. Petersburg, Russia. Translated from Inzhenerno-Fizicheskii Zhurnal, Vol. 67, Nos. 5–6, pp. 373–378, November–December, 1994. 相似文献
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L. K. Isaev 《Measurement Techniques》2007,50(11):1214-1217
The main prerequisites are considered in a historical aspect and steps ate taken in creating a world-wide metrology system
with the aim of providing conditions for the mutual recognition of measurement results.
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Translated from Izmeritel’naya Tekhnika, No. 11. pp. 59–62, November, 2007. 相似文献
9.
V. M. Piksaikin L. E. Kazakov G. G. Korolev S. G. Isaev V. A. Roshchenko M. Z. Tarasko 《Atomic Energy》2002,92(2):147-155
The relative yield of delayed neutrons and the half-life of their precursor nuclei in fissioning of 233U, 235U, and 239Pu by epithermal neutrons are measured on a setup which is based on a KG-2.5 electrostatic accelerator. The experimental samples are irradiated in a polyethylene cube, one face of which is irradiated by a neutron beam consisting of T(p, n)3He neutrons. A procedure is developed for averaging the group parameters of delayed neutrons from different series of measurements, taking account of their correlation. A comparative analysis of the data of this work and in ENDF/BVI in terms of the average half-life of the precursor nuclei of the delayed neutrons and using the dependence of the reactivity on the asymptotic period of the reactor is performed.It is shown that the data of this work agree, to within the uncertainty limits, with the recommended experimental data and differ substantially from the ENDF/BVI data. 相似文献
10.
There is now considerable evidence suggesting that alterations in the DNA methylating machinery play an important role in tumorigenesis and tumour progression. For example, focal hypermethylation and generalised genomic demethylation are features of many different types of neoplasms. It is thought that tumorigenesis and tumour progression may be caused by hypermethylation induced mutational events and silencing of genes which control cellular proliferation and/or demethylation induced reactivation of genes which may only be required during embryological development. Consequently, we have begun to investigate the role of DNA methylation and developmental genes in malignant lymphoproliferative diseases. Previously, in all cases of non-Hodgkins lymphoma and leukemia studied, we have shown that the myogenic developmental gene Myf-3 is abnormally hypermethylated. In this review we discuss the possible significance of these findings since in vitro studies suggest that Myf-3 may play an important role in control of the cell cycle and therefore lymphomagenesis. In vitro and in vivo evidence suggests that PAX genes may also have oncogenic potential. The PAX family of developmental genes are involved in cellular differentiation, proliferation and cell migration. Expression of PAX3 in particular is associated with cellular mobility. Our previous studies have indicated that alternate regional expression of PAX genes may be controlled by DNA methylation. Therefore, we have proposed that abnormal methylation profiles of PAX3 may be associated with neoplastic transformation and/or metastatic potential. Results thus far reveal that the paired box of PAX3 is abnormally hypermethylated and the homeobox abnormally hypomethylated in lymphomas and leukemias. These new findings are consistent with our postulate and support the idea that inappropriate methylation induced activation or inactivation of developmental genes such as Myf-3 and PAX3 play an important role in lymphomagenesis and disease progression and that inspection of the methylation status of other developmental genes is warranted. 相似文献