Mn-containing catalytic materials for the total combustion of toluene: The role of Mn localisation in the structure of LDH precursor

Mg/Mn/Al mixed oxide systems of similar atomic ratios close to 2/0.5/1 were obtained by calcination of Mg,Al layered double hydroxide (LDH) type precursors containing Mn either in the cationic form within the brucite layer or as permanganate anions in the interlayer. The materials were characterised with PXRD, thermal analysis, XPS, ESR, TPR and BET. In mixed oxides derived from interlayer-doped precursor PXRD identified MgO–MnO solid solution and poorly crystalline Al-rich spinel phase, while those obtained from layer-doped LDH contained a better crystalline Mn-rich spinel. Surface of both materials was covered with poorly crystalline and/or amorphous Mn⁴⁺-containing phases. Higher reducibility of this surface coat in calcined layer-doped catalyst, as compared to interlayer-doped one, was attributed to the differences in the nature of underlying crystalline phases, and was considered the chief reason for the higher catalytic activity of this catalyst in the total oxidation of toluene.     

Photovoltaic effect and carrier transport mechanisms in Hg1-Mnxtdiodes

Hg_1-xMn_xTe semiconducting semimagnetic alloy has been examined in the context of its possible applications in infrared detectors. For analysis of detector properties the intrinsic carrier concentration has been calculated as a function of temperature and crystal composition. The starting material was In-doped Hg_1-xMn_xTe grown by the modified Bridgman method. The as-grown crystals with manganese content of 12-19% were p-type with carrier concentration and mobility of 100 cm²/ Vs at 77 K. An-type layer was formed on the surface by the annealing process in saturated Hg-vapour at 270-320° for 2 hrs. Capacitance-voltage curves have C^-3 dependence on applied voltage indicating that the junction is linearly graded. From standard electrical measurements and spectral characteristics the main detector parameters were determined and compared to those of Hg_1-xCd_xTe devices. The influence of material properties on detector parameters was analyzed. In order to estimate the carrier transport mechanisms, differential resistivities and current-voltage curves were measured over a wide range of temperaturesi.e. 25 to 300 K. From the temperature dependence of the R₀A product, it was established that at high temperatures (150-300 K) the carrier transport is dominated by a recombination-generation mechanism. In low temperature region the excess current at forward bias is probably attributed to carrier tunneling via energy states distributed randomly within the forbidden gap. At reverse bias the leakage surface or volume currents dominate in the carrier transport.     

Fragment-Based Drug Discovery for RNA Targets

Rapid development within the fields of both fragment-based drug discovery (FBDD) and medicinal targeting of RNA provides possibilities for combining technologies and methods in novel ways. This review provides an overview of fragment-based screening (FBS) against RNA targets, including a discussion of the most recently used screening and hit validation methods such as NMR spectroscopy, X-ray crystallography, and virtual screening methods. A discussion of fragment library design based on research from small-molecule RNA binders provides an overview on both the currently limited guidelines within RNA-targeting fragment library design, and future possibilities. Finally, future perspectives are provided on screening and hit validation methods not yet used in combination with both fragment screening and RNA targets.     

AAOP-based dynamically reconfigurable monitoring system

A key aspect of resource management is efficient and effective deployment of available resources whenever needed. The issue typically covers two areas: monitoring of resources used by software systems and managing the consumption of resources. A key aspect of each monitoring system is its reconfigurability – the ability of a system to limit the number of resources monitored at a given time to those that are really necessary at any particular moment. The authors of this article propose a fully dynamic and reconfigurable monitoring system based on the concept of Adaptable Aspect-Oriented Programming (AAOP) in which a set of AOP aspects is used to run an application in a manner specified by the adaptability strategy. The model can be used to implement systems that are able to monitor an application and its execution environment and perform actions such as changing the current set of resource management constraints applied to an application if the application/environment conditions change. Any aspect that implements a predefined interface may be used by the AAOP-based monitoring system as a source of information. The system utilizes the concept of dynamic AOP, meaning that the aspects (which are sources of information) may be dynamically enabled/disabled.     

The Semantic Web: Collective Intelligence on the Web

The World Wide Web has turned hypertext into a success story by enabling world-wide sharing of unstructured information and informal knowledge. The Semantic Web targets the sharing of structured information and formal knowledge pursuing objectives of achieving collective intelligence on the Web. Germane to the structure of the Semantic Web is a layering and standardization of concerns. These concerns are reflected by an architecture of the Semantic Web that we present through a common use case. Semantic Web data for the use case is now found on the Web and is part of a quickly growing set of Semantic Web resources available for formal processing.     

An alternative approach to carbon nanotube sample preparation for TEM investigation

A two-stage replication technique (positive replica) is shown to be suitable for transmission electron microscopy (TEM) examination of carbon nanotubes (CNTs) and other one-dimensional nanostructures in their longitudinal direction. This method enables handling the fragile nanostructures, is fast and simple and allows to study the growth mechanism of nanofeatures, including the early stages of their growth. CNTs may also be examined when the growth layers are very thin, and even when only a few nanotubes are on a substrate. Replicas can be taken from various substrate shapes covered with nanostructures and from minute or specifically selected areas of the substrates. CNTs extracted by the replica are not disturbed, and their nanostructures are preserved. It is demonstrated that using positive replicas, HRTEM images from the nanosized carbon forms can also be obtained.     

Soldering of Mg Joints Using Zn-Al Solders

Magnesium has applications in the automotive and aerospace industries that can significantly contribute to greater fuel economy and environmental conservation. The Mg alloys used in the automotive industry could reduce mass by up to 70 pct, providing energy savings. However, alongside the advantages there are limitations and technological barriers to use Mg alloys. One of the advantages concerns phenomena occurring at the interface when joining materials investigated in this study, in regard to the effect of temperature and soldering time for pure Mg joints. Eutectic Zn-Al and Zn-Al alloys with 0.05 (wt pct) Li and 0.2 (wt pct) Na were used in the soldering process. The process was performed for 3, 5, and 8 minutes of contact, at temperatures of 425 °C, 450 °C, 475 °C, and 500 °C. Selected, solidified solder-substrate couples were cross-sectioned, and their interfacial microstructures were investigated by scanning electron microscopy. The experiment was designed to demonstrate the effect of time, temperature, and the addition of Li and Na on the kinetics of the dissolving Mg substrate. The addition of Li and Na to eutectic Zn-Al caused to improve mechanical properties. Higher temperatures led to reduced joint strength, which is caused by increased interfacial reaction.     

Existing Drugs Considered as Promising in COVID-19 Therapy

COVID-19 is a respiratory disease caused by newly discovered severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The disease at first was identified in the city of Wuhan, China in December 2019. Being a human infectious disease, it causes high fever, cough, breathing problems. In some cases it can be fatal, especially in people with comorbidities like heart or kidney problems and diabetes. The current COVID-19 treatment is based on symptomatic therapy, so finding an appropriate drug against COVID-19 remains an immediate and crucial target for the global scientific community. Two main processes are thought to be responsible for the COVID-19 pathogenesis. In the early stages of infection, disease is determined mainly by virus replication. In the later stages of infection, by an excessive immune/inflammatory response, leading to tissue damage. Therefore, the main treatment options are antiviral and immunomodulatory/anti-inflammatory agents. Many clinical trials have been conducted concerning the use of various drugs in COVID-19 therapy, and many are still ongoing. The majority of trials examine drug reposition (repurposing), which seems to be a good and effective option. Many drugs have been repurposed in COVID-19 therapy including remdesivir, favipiravir, tocilizumab and baricitinib. The aim of this review is to highlight (based on existing and accessible clinical evidence on ongoing trials) the current and available promising drugs for COVID-19 and outline their characteristics.     

Hanle Effect of Charged and Neutral Excitons in Quantum Wells

We measured magnetic field depolarization of charged and neutral exciton cw photoluminescence of a system consisting of two coupled quantum wells with a residual concentration of holes. Using the Hanle expression, we obtained exciton lifetime and electron spin relaxation time, which are in agreement with results of time-resolved experiments. We suppose that the tunneling takes place via an emission of an LO phonon and we find this process spin conserving.