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排序方式: 共有170条查询结果,搜索用时 15 毫秒
1.
Gold Nanorods,DNA Origami,and Porous Silicon Nanoparticle‐functionalized Biocompatible Double Emulsion for Versatile Targeted Therapeutics and Antibody Combination Therapy 下载免费PDF全文
2.
JW Lynch GA Kaplan RD Cohen J Tuomilehto JT Salonen 《Canadian Metallurgical Quarterly》1996,144(10):934-942
Much remains to be understood about how low socioeconomic status (SES) increases cardiovascular disease and mortality risk. Data from the Kuopio Ischemic Heart Disease Risk Factor Study (1984-1993) were used to estimate the associations between acute myocardial infarction and income, all-cause mortality, and cardiovascular mortality in a population-based sample of 2,272 Finnish men, with adjustment for 23 biologic, behavioral, psychologic, and social risk factors. Compared with the highest income quintile, those in the bottom quintile had age-adjusted relative hazards of 3.14 (95% confidence interval (CI) 1.77-5.56), 2.66 (95% CI 1.25-5.66), and 4.34 (95% CI 1.95-9.66) for all-cause mortality, cardiovascular mortality, and AMI, respectively. After adjustment for risk factors, the relative hazards for the same comparisons were 1.32 (95% CI 0.70-2.49), 0.70 (95% CI 0.29-1.69), and 2.83 (95% CI 1.14-7.00). In the lowest income quintile, adjustment for risk factors reduced the excess relative risk of all-cause mortality by 85%, that of cardiovascular mortality by 118%, and that of acute myocardial infarction by 45%. These data show how the association between SES and cardiovascular mortality and all-cause mortality is mediated by known risk factor pathways, but full "explanations" for these associations will need to encompass why these biologic, behavioral, psychologic, and social risk factors are differentially distributed by SES. 相似文献
3.
Jarno Groenesteijn Meint J. de Boer Joost C. Lötters Remco J. Wiegerink 《Microfluidics and nanofluidics》2017,21(7):126
Microfluidic devices often require channels of a specific size and shape. These devices are then made in a fabrication process that is often specialized to produce only those (and very similar) channels. As a result, devices requiring channels of different size and shape cannot easily be integrated on the same chip. This paper presents a method to fabricate microfluidic channels in a wide range of shape and size on the same chip by using a slit pattern through which the channels are etched. The fabrication process to fabricate these channels is discussed in detail, and an empirical model is presented to find the optimal slit pattern for a required size and shape. This part of the paper focusses on the channel design and fabrication. Details on the whole fabrication process and optional functionalization of the channels are presented in part I of this paper. 相似文献
4.
Christian Wolkersdorfer Rob Bowell Ingar F. Walder Steinar Nilssen Marja Liisa R?is?nen P?ivi Heikkinen Kari Pulkkinen Kirsti Korkka-Niemi Veli-Pekka Salonen Georgia Destouni Andrea Hasche Andrzej J. Witkowski A. Blachère S. Morel D. Lefort Sanda Mid?i? Irem Silajd?i? R. H. Coulton K. P. Williams Ben Rees Kevin B. Hallberg D. Barrie Johnson 《Mine Water and the Environment》2012,31(3):237-238
5.
Justin Salminen Peter Blomberg Jarno Mäkinen Lea Räsänen 《American Institute of Chemical Engineers》2015,61(9):2739-2748
Mining and metals processing are not invisible activities and are heavy industries, which require energy, water, chemicals, and land area. Recently more emphasis is given to environmental and societal aspects in mining and processing. Development of good practices with improved resource efficiency, new recovery methods and sustainability thinking are increasingly required. This work shows pH titration method for acid mine drainage (AMD) water incorporated with aqueous thermodynamic model for selective metals precipitation from complex solution. Also two examples on gold recovery methods from aqueous streams are shown: biosorption using fungal matter and solvent extraction using a task‐specific ionic liquid. By understanding chemical thermodynamics and natural phenomena, there is a better chance of developing solutions for environmental problems and new industrial processes. © 2015 American Institute of Chemical Engineers AIChE J, 61: 2739–2748, 2015 相似文献
6.
Marja Salmimaa Jyrki Kimmel Tero Jokela Peter Eskolin Toni Järvenpää Petri Piippo Kiti Müller Jarno Satopää 《Journal of the Society for Information Display》2018,26(2):98-104
A system for assisting in microneurosurgical training and for delivering interactive mixed reality surgical experience live was developed and experimented in hospital premises. An interactive experience from the neurosurgical operating theater was presented together with associated medical content on virtual reality eyewear of remote users. Details of the stereoscopic 360‐degree capture, surgery imaging equipment, signal delivery, and display systems are presented, and the presence experience and the visual quality questionnaire results are discussed. The users reported positive scores on the questionnaire on topics related to the user experience achieved in the trial. 相似文献
7.
Laura Lehtola Marjo Kauppinen Jarno Vähäniitty Marko Komssi 《Requirements Engineering》2009,14(2):113-128
A strong link between strategy and product development is important, since companies need to select requirements for forthcoming
releases. However, in practice, connecting requirements engineering (RE) and business planning is far from trivial. This paper
describes the lessons learned from four software product companies that have recognized the need for more business-oriented
long-term planning. The study was conducted using the action research approach. We identified five practices that seem to
strengthen the link between business decisions and RE. These are (1) explicating the planning levels and time horizons; (2)
separating the planning of products’ business goals from R&D resource allocation; (3) planning open-endedly with a pre-defined
rhythm; (4) emphasizing whole-product thinking; and (5) making solution planning visible. To support whole-product thinking
and solution planning, we suggest that companies create solution concepts. The purpose of the solution concept is to provide
a big picture of the solution and guide RE activities. 相似文献
8.
Outi Sipil A. Visa O. Salonen T. Erkinjuntti T. Katila 《Pattern recognition letters》2001,22(14):1475-1482
Automatic intensity-based tissue classification sets requirements for the quality of multispectral magnetic resonance (MR) images. Tests for evaluating the separability of tissue classes, and on the other hand class distances required to obtain reliable classification, are presented in this study. Intraslice, interslice and interpatient training schemes for 5-nn classification were considered. Interslice training was utilized in classification of images from 10 patients with ischemic stroke giving results of satisfactory but highly variable quality. Based on the experience with these data sets, similar tests are recommended before imaging a large patient series in order to avoid extra manual work and to obtain reliable classification results. 相似文献
9.
10.
Muikku M Rahola T Pusa S Salonen L Wahl W Roth P Haninger T Kucheida D 《Radiation protection dosimetry》2003,105(1-4):615-618
In a preliminary study, in vivo skull measurements and in vitro urine measurements of 210Pb and nulU have been performed to find out the individual, chronic exposure to waterborne natural radionuclides of a small group of Finnish people. For their domestic water, the studied individuals use water from drilled wells containing elevated concentrations of natural uranium and its daughter nuclides ((234,235,238)U, 222Rn, (226,228)Ra, 210Po, 210Pb). Enhanced 210Pb and 235U activities were observed in several people. A positive correlation is observed between the U concentration in urine (microg d(-1)) and the number of counts (cpm) in the gamma ray energy peaks originating from the decay of 235U and 234Th respectively. Calibration of the detector set-up and the determination of background sources are in progress. 相似文献