Phosphorus atomic chains,the narrowest nanostructures of black phosphorus (BP),are highly relevant to the in-depth development of BP-based one-dimensional (1D) nano-electronics components.In this study,we report a top-down route for the preparation of phosphorus atomic chains via electron beam sculpturing inside a transmission electron microscope (TEM).The growth and dynamics (i.e.,rupture and edge migration) of 1D phosphorus chains are experimentally captured for the first time.Furthermore,the dynamic behavior and associated energetics of the as-formed phosphorus chains are further investigated by density functional theory (DFT) calculations.It is hoped that these 1D BP structures will serve as a novel platform and inspire further exploration of the versatile properties of BP. 相似文献
Immunotherapy is a promising strategy to inhibit cancer progression via activation of the immune system. In immunotherapy, adjuvants as immunologic stimulants or delivery systems play a critical role in inducing the antitumor immune response and decreasing the side effects of immune stimulants. Polymer nanoparticles have attracted increasing attention as an indispensable component of immunotherapy, owing to their favorable properties, such as excellent biocompatibility and biodegradability, flexible size, high activity as immune stimulants, large surface area for binding multivalent immune ligands, and high loading capacity for immune-related components. In cancer immunotherapy, polymer nanoparticles can protect cargo from the surrounding milieu, deliver the antigens and immunostimulatory molecules to antigen-presenting cells, or stimulate robust T cell response. This review summarizes the current advancements in polymer nanoparticle adjuvants for cancer immunotherapy and predicts their prospects in fundamental and clinical studies.
View materialization is an important way of improving the performance of query
processing. When an update occurs to the source data from which a materialized view is
derived, the materialized view has to be updated so that it is consistent with the source
data. This update process is called view maintenance. The incremental method of view
maintenance, which computes the new view using the old view and the update to the
source data, is widely preferred to full view recomputation when the update is small in
size. In this paper we investigate how to incrementally maintain views in object-relational
(OR) databases. The investigation focuses on maintaining views defined in OR-SQL, a
language containing the features of object referencing, inheritance, collection, and aggregate
functions including user-defined set aggregate functions. We propose an architecture and
algorithms for incremental OR viewmaintenance. We implement all algorithms and analyze
the performance of them in comparison with full view recomputation. The analysis shows
that the algorithms significantly reduce the cost of updating a vieww hen the size of an
update to the source data is relatively small.
Received 23 May 2000 / Revised 27 March 2001 / Accepted in revised form 30 April 2001
Correspondence and offprint requests to: Jixue Liu, School of Computer and Information Science, University of South Australia, Mawson Lakes, Adelaide SA5084, Australia.
Email: jixue.liu@unisa.edu.auau 相似文献
Irrelevant updates in a database are updates to source data that do not affect a view defined over the source data. Self-maintainable updates are ones for which the view can be updated, without having to access source data, when the source data from which the view is derived is updated. In this paper we derive necessary and sufficient conditions for an update to be irrelevant or self-maintainable when the source data is a graph and the view is defined to be the transitive closure of the graph. 相似文献