Structure and evolution of Indian physics co-authorship networks

We trace the evolution of Indian physics community from 1919 to 2013 by analyzing the co-authorship network constructed from papers published by authors in India in American Physical Society (APS) journals. We make inferences on India’s contribution to different branches of Physics and identify the most influential Indian physicists at different time periods. The relative contribution of India to global physics publication (research) and its variation across subfields of physics is assessed. We extract the changing collaboration pattern of authors between Indian physicists through various network measures. We study the evolution of Indian physics communities and trace the mean life and stationarity of communities by size in different APS journals. We map the transition of authors between communities of different sizes from 1970 to 2013, capturing their birth, growth, merger and collapse. We find that Indian–Foreign collaborations are increasing at a faster pace compared to the Indian–Indian. We observe that the degree distribution of Indian collaboration networks follows the power law, with distinct patterns between Physical Review A, B and E, and high energy physics journals Physical Review C and D, and Physical Review Letters. In almost every measure, we observe strong structural differences between low-energy and high-energy physics journals.

     

Cryptolepis sanguinolenta: an ethnobotanical approach to drug discovery and the isolation of a potentially useful new antihyperglycaemic agent

Hypoxia induces an increase in PMN adherence to endothelial cells for which an interaction between ICAM-1 and CD18/CD11b has been demonstrated. Since PECAM-1 has been shown to be involved in PMN transmigration through the endothelium and to increase the binding capacity of leukocyte CD18/CD11b, the role of this molecule in the hypoxia-induced PMN adherence was investigated. Hypoxia did not change the total surface expression of PECAM-1 on HUVEC and did not change the cell-cell border localization of this molecule as TNF-alpha did. In addition, blocking anti-PECAM-1 antibodies could not inhibit the increased adherence of unstimulated human PMN to hypoxia-incubated HUVEC while anti-ICAM-1 partially inhibited this process. These results indicate that PECAM-1 is probably not involved in the hypoxia-induced PMN adherence to endothelial cells.     

Two new naphthoquinones with antiviral activity from Rhinacanthus nasutus

Two new naphthoquinones, rhinacanthin-C (1) and rhinacanthin-D (2), exhibit inhibitory activity against cytomegalovirus (CMV), with EC50 values of 0.02 and 0.22 microgram/mL, respectively, against human CMV. They were isolated from the medicinal plant Rhinacanthus nasutus (Acanthaceae). The structures of the compounds were determined by analysis of their spectroscopic data, in particular, 2D NMR.