Comparative toxicity of 24 manufactured nanoparticles in human alveolar epithelial and macrophage cell lines

Background  

A critical issue with nanomaterials is the clear understanding of their potential toxicity. We evaluated the toxic effect of 24 nanoparticles of similar equivalent spherical diameter and various elemental compositions on 2 human pulmonary cell lines: A549 and THP-1. A secondary aim was to elaborate a generic experimental set-up that would allow the rapid screening of cytotoxic effect of nanoparticles. We therefore compared 2 cytotoxicity assays (MTT and Neutral Red) and analyzed 2 time points (3 and 24 hours) for each cell type and nanoparticle. When possible, TC50 (Toxic Concentration 50 i.e. nanoparticle concentration inducing 50% cell mortality) was calculated.     

绿色瓶子 绿色营销

收缩套标生产商Packastar去年为美宝莲生产了2000万个PLA标签,节省了相当于1.75万加仑的汽油。2007年,美宝莲使用了2千万个PLA标签,节省了相当于17,500加仑的汽油。与美宝莲一样,可口可乐也在去年夏天,为它的可口可乐世界交互店使用了PLA收缩标签,而且将继续这么做下去。现在有20%的业务来自于PLA项目的纽约