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Joshua Vaughan Joel Fortgang William Singhose Jeffrey Donnell Thomas Kurfess 《Mechatronics》2008,18(4):179-186
It is commonly accepted that hands-on experiences increase both learning and enjoyment during coursework. Mechatronics projects provide both interesting and relevant hands-on experiences for a wide range of topics including design processes, basic mechatronics concepts, technical communication, and working in a group environment. ME2110: Creative Decisions and Design at Georgia Tech integrates mechatronics and technical communication into a sophomore level mechanical design class. This paper describes the course in detail, highlighting the course goals and layout, tools provided to the students, industry involvement, and the main challenges of administering such a course. 相似文献
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Surface treatments used in daily manufacturing of parts for the automotive industry are selected to serve functional and decorative requirements achieved of mass production. Increased loads (mechanical, thermal etc.), longer life time, weight reduction, friction reduction, and corrosion resistance are demanded for modern automotive systems. Within the last decade, improved and new deposition techniques were developed in PVD, PECVD, thermochemical heat treatment and thermal spraying. These new treatments are becoming more and more common in powertrain and engine applications. Generating optimized surfaces for different types of substrate materials (e.g. Al‐ alloys, case hardened steels etc.) and geometries (e.g. bores) also impacts the running costs. Due to the new developments within these competing surface treatments, it becomes more and more common to substitute traditional treatment‐substrate‐systems with advanced treatments. Both the application potential and selected examples of different surface treatments will be shown. Aspects of the internal coating of bores inside the engine by plasma spraying, features of the corrosion protection of parts for the powertrain by the IONITOX process and piston ring treatments are discussed in more detail. 相似文献
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Youdong Lin Joshua A. Enszer Mark A. Stadtherr 《Computers & Chemical Engineering》2008,32(8):1714-1725
The two-point boundary value problem (TPBVP) occurs in a wide variety of problems in engineering and science, including the modeling of chemical reactions, heat transfer, and diffusion, and the solution of optimal control problems. A TPBVP may have no solution, a single solution, or multiple solutions. A new strategy is presented for reliably locating all solutions of a TPBVP. The method determines narrow enclosures of all solutions that occur within a specified search interval. Key features of the method are the use of a new solver for parametric ODEs, which is used to produce guaranteed bounds on the solutions of nonlinear dynamic systems with interval-valued parameters and initial states, and the use of a constraint propagation strategy on the Taylor models used to represent the solutions of the dynamic system. Numerical experiments demonstrate the use and computational efficiency of the method. 相似文献
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Justin McKetney Daniel J. Panyard Sterling C. Johnson Cynthia M. Carlsson Corinne D. Engelman Joshua J. Coon 《Proteomics. Clinical applications》2021,15(2-3):2000072
Proteomic analysis of cerebrospinal fluid (CSF) holds great promise in understanding the progression of neurodegenerative diseases, including Alzheimer's disease (AD). As one of the primary reservoirs of neuronal biomolecules, CSF provides a window into the biochemical and cellular aspects of the neurological environment. CSF can be drawn from living participants allowing the potential alignment of clinical changes with these biochemical markers. Using cutting-edge mass spectrometry technologies, we perform a streamlined proteomic analysis of CSF. We quantify greater than 700 proteins across 10 pairs of age- and sex-matched participants in approximately one hour of analysis time each. Using the paired participant study structure, we identify a small group of biologically relevant proteins that show substantial changes in abundance between cognitive normal and AD participants, which were then analyzed at the peptide level using parallel reaction monitoring experiments. Our findings suggest the utility of fractionating a single sample and using matching to increase proteomic depth in cerebrospinal fluid, as well as the potential power of an expanded study. 相似文献
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Stephen M. Walls John V. Kucsera Joshua D. Walker Taylor W. Acee Nate K. McVaugh Daniel H. Robinson 《Computers & Education》2010
Instructors in higher education are disseminating instructional content via podcasting, as many rally behind the technology’s potential benefits. Others have expressed concern about the risks of deleterious effects that might accompany the adoption of podcasting, such as lower class attendance. Yet, relatively few studies have investigated students’ perceptions of podcasting for educational purposes, especially in relation to different podcasting forms: repetitive and supplemental. The present study explored students’ readiness and attitudes towards these two forms of podcasting to provide fundamental information for future researchers and educators. The results indicated that students may not be as ready or eager to use podcasting for repetitive or supplemental educational purposes as much as we think they are, but they could be persuaded. 相似文献
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