A Stable Low Power Dissipating 9 T SRAM for Implementation of 4 × 4 Memory Array with High Frequency Analysis

Wireless Personal Communications - Today’s high speed data processing and memory storage operations demand immediate data write and retrieval to meet up to benchmark. To act as a volatile or...     

Electrospun microporous gelatin–polycaprolactone blend tubular scaffold as a potential vascular biomaterial

The work reported involved the fabrication of an electrospun tubular conduit of a gelatin and polycaprolactone (PCL) blend as an adventitia‐equivalent construct. Gelatin was included as the matrix for increased biocompatibility with the addition of PCL for durability. This is contrary to most of the literature available for biomaterials based on blends of gelatin and PCL where PCL is the major matrix. The work includes the assiduous selection of key electrospinning parameters to obtain smooth bead‐free fibres with a narrow distribution of pore size and fibre diameter. Few reports elucidate the optimization of all electrospinning parameters to fabricate tubular conduits with a focus on obtaining homogeneous pores and fibres. This stepwise investigation would be unique for the fabrication of gelatin–PCL electrospun tubular constructs. The fabricated microfibrous gelatin–PCL constructs had pores of size ca 50–100 μm reportedly conducive for cell infiltration. The measured value of surface roughness of 57.99 ± 17.4 nm is reported to be favourable for protein adhesion and cell adhesion. The elastic modulus was observed to be similar to that of the tunica adventitia of the native artery. Preliminary in vitro and in vivo biocompatibility tests suggest safe applicability as a biomaterial. Minimal cytotoxicity was observed using MTT assay. Subcutaneous implantation of the scaffold demonstrated acute inflammation which decreased by day 15. The findings of this study could enable the fabrication of smooth bead‐free microfibrous gelatin–PCL tubular construct as viable biomaterial which can be included in a bilayer or a trilayer scaffold for vascular tissue engineering. © 2019 Society of Chemical Industry     

Über die Anwendung von Ionensensitiven Feldeffekttransistoren zur Untersuchung von Korrosionsvorgängen

On the application of ion sensitive field-effect transistors for the investigation of corrosion phenomena Ion sensitive field-effect transistors (ISFET) are chemical sensors based on semiconductor technology. They exhibit small dimensions, a plane measuring surface and have short response times. Thus, they are very suitable for the determination of local changes of the pH value at electrochemical corrosion studies. The described in this paper experimental set-up allows in situ measurements of the pH value by means of ISFET sensors in amounts of liquids below 1 mm³; the active surface area of the material under test may be below 1 mm². In model tests preferably changes of the pH value of dist. water due to the corrosion of steel St 38 have been investigated. After an initial short-time rise caused by oxygen reduction a decay of the pH value to pH = 3 ?4 was obseved. Furthermore, ISFET sensors have been used as a potential probe for electrochemical polarization measurements in low conductive media. It was shown, that the dynamic behaviour of potentiostatic control circuits may be influenced favourably by the low output resistance of the ISFET.     

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Selective interactions among the multiple connexin proteins expressed in the vertebrate lens: the second extracellular domain is a determinant of compatibility between connexins

Gap junctions are collections of intercellular channels composed of structural proteins called connexins (Cx). We have examined the functional interactions of the three rodent connexins present in the lens, Cx43, Cx46, and Cx50, by expressing them in paired Xenopus oocytes. Homotypic channels containing Cx43, Cx46, or Cx50 all developed high conductance. heterotypic channels composed of Cx46 paired with either Cx43 or Cx50 were also well coupled, whereas Cx50 did not form functional channels with Cx43. We also examined the functional response of homotypic and heterotypic channels to transjunctional voltage and cytoplasmic acidification. We show that all lens connexins exhibited sensitivity to cytoplasmic acidification as well as to voltage, and that voltage-dependent closure of heterotypic channels for a given connexin was dramatically influenced by its partner connexins in the adjacent cell. Based on the observation that Cx43 can discriminate between Cx46 and Cx50, we investigated the molecular determinants that specify compatibility by constructing chimeric connexins from portions of Cx46 and Cx50 and testing them for their ability to form channels with Cx43. When the second extracellular (E2) domain in Cx46 was replaced with the E2 of Cx50, the resulting chimera could no longer form heterotypic channels with Cx43. A reciprocal chimera, where the E2 of Cx46 was inserted into Cx50, acquired the ability to functionally interact with Cx43. Together, these results demonstrate that formation of intercellular channels is a selective process dependent on the identity of the connexins expressed in adjacent cells, and that the second extracellular domain is a determinant of heterotypic compatibility between connexins.     

Crack Development in Individually Quick Frozen Cut and Peel Carrots

ABSTRACT:  Crack development during freezing (CDF) is one of the major challenges in individually quick frozen (IQF) cut and peel carrot processing. The effects of processing and freezer storage on crack development were examined on the cut and peel carrot variety, Sugarsnax. Carrot samples were removed from the major processing steps, the trans-slicer, the shaper, the blancher, and the dryer, and examined for crack development by measuring percentage cracked, crack morphology, total soluble solids, moisture levels, and membrane injury index immediately after processing. These parameters were also examined following 20 wk of standard freezer storage for cut and peels. Approximately 2% of nonprocessed carrots were cracked compared to 45% of carrots after the initial trans-slicing stage. As the processing continued, cracking decreased due to the removal of the outer epidermis to 16% of the finished product. This suggests that CDF was initiated at the 1st processing stage. Crack width and depth were 2.3 and 2.6 mm, respectively, at the trans-slicer stage and decreased to 1.1 and 1.8 mm at the end of the line. It was found that CDF was further exacerbated by freezer storage due to inefficient water removal at the dryer stage. Crack width and depth increased to 1.5 and 3.0 mm after 20 wk for freezer storage. Root size also played a role in CDF, suggesting that larger pieces are more susceptible to crack development. Total soluble solid concentrations did not play a role in crack formation during cut and peel processing.     

High resolution spherical microwave holography

A practical technique is developed to determine the electric and/or magnetic field on objects and sources inside a spherical measurement surface. The technique, known as spherical microwave holography (SMH), provides a nondestructive, nonintrusive method of point-by-point evaluation of antennas and radomes over their spatial extent. The resolution capability of SMH is developed and demonstrated by measurements. Resolution in SMH is only limited by the measurement system's capabilities. Dielectric and metallic obstacles on the surface of a radome are located and identified. Resolution as small as 0.33λ₀ is demonstrated