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1.
Neural Processing Letters - The uncertainty caused mainly by the deficiency of precision and data, artificial/human-made errors, information accessed from expert opinions or very miniature size of... 相似文献
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A crack-tip screening analysis of cleavage fracture of steel is developed. The analysis incorporates evidence that reinitiation
of an arrested cleavage crack requires less stress intensity than cleavage initiation from a fatigue precrack. Fractographic
evidence as well as metallographic sectioning of arrested cracks have previously shown that the mechanism of rapid crack propagation
by cleavage is affected strongly by partial crack-plane deflection which leaves unbroken ligaments in its wake. The tearing
of these ligaments by dimple rupture is the dominant energy-absorbing mechanism. Earlier etch-pit experiments using an Fe-Si
alloy showed that the crack-tip stress intensity based on plastic zone size is extremely low. These observations are incorporated
into a model in which cleavage crack reinitiation is analyzed using a sharp crack that is shielded by a distribution of pinching
forces along its faces. During reloading of the arrested crack, the ligaments restrict crack-tip blunting, leading to higher
local stresses. As a result, lower stress intensities are needed for reinitiation than for initiation from a fatigue precrack. 相似文献
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Satisfaction of twin objectives of maximization of Mn along with minimization of PDI do not necessarily guarantee the maximization of concentration of desired species in a semibatch epoxy polymerization process. As the final product consists of a number of polymer species, a need is felt to perform an advanced optimization study to come up with such process conditions for which the selective growth of a particular polymer species is maximized in minimum possible processing time and the population of other species should be at their lowest values. These above-mentioned conflicting objectives frame the platform for a multi-objective optimization problem, which is solved here using a real-coded non-dominated sorting genetic algorithm or NSGA II and Pareto optimal solutions are obtained. The decision variables are discrete addition rates of various ingredients, e.g. the amount of addition of bisphenol-A (a monomer), sodium hydroxide and epichlorohydrin at different time steps. All species balance equations, bounds on Mn, PDI and addition amounts are treated as constraints. Results are very promising in terms of optimized operations for selective enhancement of desired polymer species for the epoxy polymerization process. Total additions are kept very close to available experimental conditions to minimize probable extrapolation errors. It has been observed that preferential oligomer production is extremely difficult for epoxy polymerization. Lower chain polymers are the only choice for a good quality, stable polymer product. 相似文献
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Neog D.K. Pattnaik S.S. Panda D.C. Devi S. Khuntia B. Dutta M. 《Antennas and Propagation Magazine, IEEE》2005,47(3):60-65
This paper deals with the design of a multi-slot hole-coupled microstrip antenna on a substrate of 2 mm thickness that gives multi-frequency (wideband) characteristics. The Method of Moments (MoM)-based IE3D software was used to simulate the results for return loss, VSWR, the Smith chart, and the radiation patterns. A tunnel-based artificial neural network (ANN) was also developed to calculate the radiation patterns of the antenna. The radiation patterns were measured experimentally at 10.5 GHz and 12 GHz. The experimental results were in good agreement with the simulated results from IE3D and those of the artificial neural network. A new method of using a genetic algorithm (GA) in an artificial neural network is also discussed. This new method was used to calculate the resonant frequency of a single-shorting-post microstrip antenna. The resonant frequency calculated using the genetic-algorithm-coupled artificial neural network was compared with the analytical and experimental results. The results obtained were in very good agreement with the experimental results. 相似文献
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Densification of a-Sic powders with no premixed sintering aids (type 1) and with premixed B and C (type 2) was investigated by sintering them at 2150° to 2200°C for 30 min. Flexure strengths, Weibull moduli, and fracture flaws were characterized for type 2 α-SiC only. The results were compared with those for a state-of-the-art sintered a-Sic material. 相似文献
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Ozone exposure results in an acute decrease in the serum levels of thyroid hormones; the physiologic sequelae of this are unclear. Whereas thyroid hormone supplementation appears to benefit pulmonary function in septic, oxyradical models of injury, thyroid hormone increases ozone toxicity. We demonstrated an increase in metabolic rate and pulmonary injury in lungs from ozone exposed, T3 treated animals. This was evidenced by an increase in pulmonary weight gain, vascular perfusion pressure, and decrease in compliance in the supplemented animals. However, an increase in alkane generation, as an index of lipid peroxidation, was not seen in the ozone exposed, hormonally treated animals. This suggests that although thyroid hormone supplementation increases metabolic rate and ozone toxicity, an increased rate of lipid peroxidation plays a minimal role. 相似文献
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JA Moshier E Malecka-Panas H Geng J Dosescu J Tureaud M Skunca AP Majumdar 《Canadian Metallurgical Quarterly》1995,55(22):5358-5365
Ornithine decarboxylase (ODC) has been shown to be oncogenic in transfected NIH/3T3 cells overexpressing the enzyme from a heterologous promoter. These cells, designated as NODC-2 cells, acquire proliferative properties associated with tumorigenic transformation such as loss of contact inhibition, decreased population doubling time, anchorage-independent growth, and tumor production in nude mice. At least one of these parameters, loss of contact inhibition, remains dependent on elevated ODC levels. We have used these cells to investigate the molecular mechanisms by which ODC overexpression drives cell transformation and to examine the involvement of other proto-oncogene products in this process. An interaction between ODC overexpression and the epidermal growth factor receptor (EGF-R) was suggested initially by the elevation of both basal (300%) and ligand-induced (457%) EGF-R tyrosine kinase activities in NODC-2 cells compared to similarly treated control NLK cells. Disruption of EGF-R mediated signal transduction in NODC-2 cells both by treatment with tyrphostin-25 or by transfection with a vector expressing a dominant negative EGF-R mutant resulted in reacquisition of contact-inhibited growth and suppression of anchorage-independent, clonogenic growth in soft agar. We conclude that ODC-induced transformation of NIH/3T3 cells is mediated, at least partly, by alterations in EGF-R signal transduction activity. 相似文献