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1.
The repellent action of neem oil was evaluated against sand flies under laboratory and field conditions. Concentrations of 2% neem oil mixed in coconut or mustard oil provided 100% protection against Phlebotomus argentipes throughout the night under field conditions; against Phlebotomus papatasi it repelled sand flies for about 7 h in the laboratory. Neem oil is an indigenous product and a low-cost alternative for personal protection against sand fly bites.  相似文献   
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Results of eight multicenter, randomized, placebo-controlled, double-blind, parallel-group studies were pooled to assess the efficacy of the angiotensin II-receptor blocker irbesartan over the dose range of 1 to 900 mg. A total of 2955 adults with a seated diastolic blood pressure of 95 to 110 mm Hg were randomized to treatment with oral irbesartan once daily or placebo for 6 to 8 weeks. Office blood pressure was measured at trough (24+/-3 hours after the last dose) and peak (3+/-1 hours after the last dose) by mercury sphygmomanometry. Demographic characteristics (mean blood pressure; 151/101 mm Hg; mean age, 54 years; 63% male; and 82% white) were similar across all dose groups. After the groups were pooled, antihypertensive efficacy was assessed by therapeutic response (trough seated diastolic blood pressure <90 mm Hg or a reduction from baseline of > or = 10 mm Hg) and by modeling of the maximum reductions in trough and peak seated diastolic and systolic blood pressure. Antihypertensive effects increased with increasing doses and reached a plateau at > or = 300 mg. Irbesartan 150 mg provided placebo-subtracted reductions in trough seated systolic and diastolic blood pressure of approximately 8 and approximately 5 mm Hg, respectively, with 56% of patients displaying a favorable response. In conclusion, irbesartan provides clinically significant blood pressure lowering, with a clear relationship between (log) dose and antihypertensive effect.  相似文献   
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Determination of the thermo-mechanical structure of the crust for seismically active regions using available geophysical and geological data is of great importance. The most important feature of the intraplate earthquakes in the Indian region are that the seismicity occurs within the entire crust. In Latur region of India an earthquake occurred in the upper crust. In such situations, quantifying the uncertainties in seismogenic depths becomes very important. The stochastic heat conduction equation has been solved for different sets of boundary conditions, an exponentially decreasing radiogenic heat generation and randomness in thermal conductivity. Closed form analytical expressions for mean and variance in the temperature depth distribution have been used and an automatic formulation has been developed in Matlab for computing and plotting the thermal structure. The Matlab toolbox presented allows us to display the controlling thermal parameters on the screen directly, and plot the subsurface thermal structure along with its error bounds. The software can be used to quantify the thermal structure for any given region and is applied here to the Latur earthquake region of India.  相似文献   
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In this paper, performance of piezoelectrically actuated pyramidal valveless micropumps is studied experimentally in detail. Valveless micropumps based on silicon and glass substrate are fabricated using MEMS technology. Two different sizes of micropumps having overall dimensions of 5 mm × 5 mm × 1 mm and 10 mm × 10 mm × 1 mm are fabricated and characterized. In the fabricated micropumps, the thickness of silicon diaphragm is <20 µm which gives the advantage of operating pump at low voltage with excellent stability and consistency. The performance of micropumps in terms of flowrate and backpressure is evaluated for a wide range of driving frequency and actuating voltages. The maximum flowrate of water in the 10-mm micropump is 355 µl/min and backpressure of 3.1 kPa at zero flowrate for an applied voltage of 80 V at frequency 1.05 kHz. The reported micropumps have low footprint, high flowrate and backpressure. Thus, these micropumps are especially suited for biological applications as these can withstand adequate amount of backpressure. Comparative study of the performance of these micropumps with those available in the literature brings out the efficacy of these micropumps.  相似文献   
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Due to rapid construction, necessity for raw materials of concrete, especially coarse aggregate, tends to increase the danger of early exhaustion of the natural resources. An alternative source of raw materials would perhaps delay the advent of this early exhaustion. Recycled coarse aggregate (RCA) plays a great role as an alternative raw material that can replace the natural coarse aggregate (NCA) for concrete. Previous studies show that the properties of RCA concrete are inferior in quality compared to NCA concrete. This article attempts to study the improvement of properties of RCA concrete with the addition of bacteria named as Bacillus subtilis. The experimental investigation was carried out to evaluate the improvement of the compressive strength, capillary water absorption, and drying shrinkage of RCA concrete incorporating bacteria. The compressive strength of RCA concrete is found to be increased by about 20% when the cell concentration of B. subtilis is 106 cells/ml. The capillary water absorption as well as drying shrinkage of RCA are reduced when bacteria is incorporated. The improvement of RCA concrete is confirmed to be due to the calcium carbonate precipitation as observed from the microstructure studies carried out on it such as EDX, SEM, and XRD.  相似文献   
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Journal of Mechanical Science and Technology - A dielectric fluid plays a significant role on the machining efficiency of Electric discharge machining (EDM). Two phase (liquid-air) dielectric...  相似文献   
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In this work, the physical properties of nanocrystalline samples of La0.7Sr0.3Mn1−xFexO3 (0.0 ≤ x ≤ 0.20) perovskite manganites synthesized by the reverse micelle (RM) technique were explored in detail. The phase purity, crystal structure, and crystallite size of the samples were determined using X-ray diffraction (XRD) and Fourier transform infrared (FTIR) spectroscopy. All the samples had rhombohedral crystal structure and crystallite size increased with increase in Fe content in La0.7Sr0.3MnO3. The scanning electron micrographs (SEMs) exhibited smooth surface morphology and nonuniform shape of the particles. The optical properties studied using UV-visible absorption spectroscopy revealed a decrease in the absorbance and optical band gap with an increase in Fe content in La0.7Sr0.3MnO3 compound. The temperature-dependent resistivity measurements revealed semiconducting nature of x = 0 and 0.1 samples up to the studied temperature range, while a metal-to-insulator transition was observed at higher Fe doping. Magnetic studies revealed weak ferromagnetism in all the samples and a reduction in the maximum magnetization with an increase in Fe content. A close correlation between electrical transport and magnetic properties was observed with the doping of Fe ion in La0.7Sr0.3MnO3 at Mn site. These results advocate strong interactions associated with the double exchange mechanism among Fe3+ and Mn3+ ions.  相似文献   
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