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排序方式: 共有362条查询结果,搜索用时 15 毫秒
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Journal of Mechanical Science and Technology - The idea of integral calculus is used in traditional milling force prediction methods. In the traditional method, the milling cutter is divided into... 相似文献
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A Barbarino S Colasanti SM Corsello MA Satta S Della Casa CA Rota R Tartaglione A Barini 《Canadian Metallurgical Quarterly》1995,80(4):1329-1332
This study investigated the acute effects of interferon-alpha 2 (IFN-alpha 2) on hormonal secretion in adult patients affected by a chronic myeloproliferative syndrome and tried to shed some light on the mechanism by which IFN-alpha 2 stimulates cortisol and GH secretion in humans. We compared the pattern of IFN-alpha 2-induced cortisol and GH release with that elicited after the same challenge given subsequent to pretreatment with dexamethasone (Dex). We studied eight patients affected by a chronic myeloproliferative syndrome (thrombocythemia) who had been selected for treatment with IFN-alpha 2. Four sets of experiments were performed: 1) 2 mL iv saline was given at 0800 h in eight cases; 2) 3 x 10(6) IU iv IFN-alpha 2 was given at 0800 h in eight cases; 3) 3 x 10(6) IU iv IFN-alpha 2 was given at 0800 h after pretreatment with 1.5 mg Dex (1 mg at midnight the previous night and 0.5 mg at 0700 h on the day of the test) in six cases; and 4) 2 mL iv saline was given at 0800 h after the same Dex pretreatment in four cases. Cortisol and GH were measured in plasma samples drawn at 30-min intervals between 0800 and 1300 h. Acute iv administration of IFN-alpha 2 stimulated the release of both cortisol and GH in each patient with a significant increment vs. control values, as assessed by areas under the curve. The administration of Dex significantly decreased basal plasma cortisol secretion and abolished cortisol response to IFN-alpha 2 administration. These data suggest that the stimulatory action of IFN-alpha 2 on cortisol release is mediated via a modulation of the activity of the hypothalamic-pituitary axis rather than through a direct effect at the level of the adrenal cortex. After Dex plus saline administration, no significant effect was observed on plasma GH levels, which remained low. Dex administration significantly decreased GH response to IFN-alpha 2. These data suggest that a hypothalamic or pituitary stimulation (or both) is involved in the mechanism of IFN-alpha 2-induced GH secretion. It remains to be established whether IFN-alpha 2 directly stimulates pituitary somatotropic cells or whether the cytokine exerts a stimulatory action on GH secretion by indirectly modulating the hypothalamic or pituitary activity. In conclusion, acute iv administration of IFN-alpha 2 represents a potent stimulus for cortisol and GH secretion in adult human subjects.(ABSTRACT TRUNCATED AT 400 WORDS) 相似文献
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多线程软件由于进程间共享使用资源而极易发生死锁这一严重的并发漏洞.通过Petri网模型对多线程软件进行建模,并利用混合整数规划技术检测其漏洞.目前,使用互斥锁的多线程软件可通过Gadara网建模和检测.而使用信号量的多线程软件,虽可用S*PR网建模,但是尚未有理论支撑混合整数规划用于其漏洞检测.定义了S*PR网的一个子类——SEM-S*PR网,它允许资源库所初始标志大于1且分支可对称地使用资源,进而可建模一类使用信号量的多线程软件.依据结构特点,证明了该网保持活性的充分必要条件是网运行过程中所有信标始终非空.此结论是混合整数规划用于SEM-S*PR网建模的多线程软件的并发漏洞检测的理论基础. 相似文献
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In recent years,trap-related interfacial transport phenomena have received great attention owing to their potential applications in resistive switching devices and photo detectors.Not long ago,one new type of memristive interface that is composed of F-doped SnO2 and Bi2S3 nano-network layers has demonstrated a bivariate-continuous-tunable resistance with a swift response comparable to the one in neuron synapses and with a brain-like memorizing capability.However,the resistive mechanism is still not clearly understood because of lack of evidence,and the limited improvement in the development of the interfacial device.By combining I-V characterization,electron energy-loss spectroscopy,and firstprinciple calculation,we studied in detail the macro/micro features of the memristive interface using experimental and theoretical methods,and confirmed that its atomic origin is attributed to the traps induced by O-doping.This implies that impurity-doping might be an effective strategy for improving switching features and building new interfacial memristors. 相似文献
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提出了一种频率特性测试方法,该方法以Multitone信号作为激励信号来减少测试时间,并运用相关分析法作为数据处理方法来提高测试精度;以某型舵机系统为例,对该方法进行了实验验证;实验结果表明,其测试精度与传统的测试方法基本相同,测试时间减少一半;该方法能有效减少噪声对测量结果的影响,适合频率特性的快速高精度测试。 相似文献
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An approach for moving object recognition based on BPR and CI 总被引:1,自引:0,他引:1
A recognition and classification method of multiple moving objects in traffic based on the combination of the Biomimetic Pattern
Recognition (BPR) and Choquet Integral (CI) is proposed. The recognition process consists of three stages. At the first stage,
vehicles and pedestrians are detected in video images and the area, the shape and the velocity features are obtained by classical
methods. At the second stage, BPR is used to classify the Zernike moments extracted at the first stage. At the last stage,
CI is then adopted for multi-features fusion based on the output of BPR, and the area and the velocity features obtained at
the first stage to improve the recognition accuracy. Experiment results show that this approach is efficient. 相似文献
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本文应用量子化学密度泛函理论(DFT)研究了2-(4-甲氧基苯基)亚肼基乙酸与乙醛酸的反应机理及动力学行为,并研究了不同取代基对反应的影响.在RB3LYP/6-31G*水平上,优化了各反应通道的反应物、中间体、过渡态及产物的几何构型,计算了各驻点的振动频率、零点能和电荷分布.计算结果表明,该反应有2条反应通道,分别生成(2Z)和(2E)-3(4-甲氧基苯基二氮烯基)丙烯酸.产物发生了键长的平均化和电荷的重新分布.两反应通道具有相同的反应入口,Z式产物为主要产物,2-(4-甲氧基苯基)亚肼基乙酸中苯环对位被给电子基团取代,有利于反应进行. 相似文献