全文获取类型
收费全文 | 3360篇 |
免费 | 128篇 |
国内免费 | 2篇 |
专业分类
电工技术 | 33篇 |
综合类 | 5篇 |
化学工业 | 607篇 |
金属工艺 | 39篇 |
机械仪表 | 66篇 |
建筑科学 | 154篇 |
矿业工程 | 4篇 |
能源动力 | 55篇 |
轻工业 | 418篇 |
水利工程 | 35篇 |
石油天然气 | 1篇 |
无线电 | 226篇 |
一般工业技术 | 470篇 |
冶金工业 | 1112篇 |
原子能技术 | 11篇 |
自动化技术 | 254篇 |
出版年
2024年 | 5篇 |
2023年 | 30篇 |
2022年 | 69篇 |
2021年 | 93篇 |
2020年 | 71篇 |
2019年 | 56篇 |
2018年 | 73篇 |
2017年 | 63篇 |
2016年 | 73篇 |
2015年 | 56篇 |
2014年 | 89篇 |
2013年 | 153篇 |
2012年 | 130篇 |
2011年 | 198篇 |
2010年 | 153篇 |
2009年 | 168篇 |
2008年 | 193篇 |
2007年 | 158篇 |
2006年 | 125篇 |
2005年 | 119篇 |
2004年 | 125篇 |
2003年 | 97篇 |
2002年 | 111篇 |
2001年 | 76篇 |
2000年 | 75篇 |
1999年 | 72篇 |
1998年 | 127篇 |
1997年 | 109篇 |
1996年 | 90篇 |
1995年 | 75篇 |
1994年 | 92篇 |
1993年 | 58篇 |
1992年 | 44篇 |
1991年 | 19篇 |
1990年 | 33篇 |
1989年 | 24篇 |
1988年 | 35篇 |
1987年 | 16篇 |
1986年 | 9篇 |
1985年 | 17篇 |
1984年 | 9篇 |
1983年 | 14篇 |
1982年 | 12篇 |
1981年 | 16篇 |
1980年 | 6篇 |
1979年 | 8篇 |
1978年 | 8篇 |
1977年 | 11篇 |
1976年 | 12篇 |
1974年 | 4篇 |
排序方式: 共有3490条查询结果,搜索用时 31 毫秒
1.
Karolina Storesund Francine Amon Anne Steen‐Hansen Shayesteh Haghighatpanah Ida Larsson 《火与材料》2021,45(1):181-190
The aim of this exploratory study has been to investigate the fire properties and environmental aspects of different upholstery material combinations, mainly for domestic applications. An analysis of the sustainability and circularity of selected textiles, along with lifecycle assessment, is used to qualitatively evaluate materials from an environmental perspective. The cone calorimeter was the primary tool used to screen 20 different material combinations from a fire performance perspective. It was found that textile covers of conventional fibres such as wool, cotton and polyester, can be improved by blending them with fire resistant speciality fibres. A new three‐dimensional web structure has been examined as an alternative padding material, showing preliminary promising fire properties with regard to ignition time, heat release rates and smoke production. 相似文献
2.
Dr. Maria L. Di Paolo Dr. Michael S. Christodoulou Dr. Alessandra M. Calogero Dr. Luca Pinzi Prof. Giulio Rastelli Prof. Daniele Passarella Prof. Graziella Cappelletti Prof. Lisa Dalla Via 《ChemMedChem》2019,14(18):1641-1652
A series of 2-phenyloxazoles bearing an amide group at position 4 were designed and synthesized for evaluation as potential inhibitors of human recombinant monoamine oxidases (hrMAOs). Results of kinetics experiments demonstrated that all compounds behave as competitive MAO inhibitors, with good selectivity toward the MAO-B isoform. The most potent and selective derivatives are characterized by inhibition constant (Ki) values in the sub-micromolar range and a good selectivity index (Ki MAO-A/Ki MAO-B>50). Some derivatives were also found to be able to inhibit MAO activity in nerve growth factor (NGF)-differentiated PC12 cells, taken as a model of neuronal cells. In particular, 2-(2-hydroxyphenyl)-N-phenyloxazole-4-carboxamide (compound 4 a ) may be a promising new scaffold, exerting the highest selectivity and inhibitory effect toward MAOs in NGF-differentiated PC12 cell lysates, without compromising cell viability. Molecular docking analysis allowed a rationalization of the experimentally observed binding affinity and selectivity. 相似文献
3.
Dr. Yahu A. Liu Dr. Qihui Jin Qiang Ding Dr. Xueshi Hao Tingting Mo Shanshan Yan Dr. Yefen Zou Dr. Zhihong Huang Xiaoyue Zhang Wenqi Gao Dr. Tom Y.-H. Wu Chun Li Dr. Badry Bursalaya Dr. Michael Di Donato Dr. You-Qing Zhang Lisa Deaton Dr. Weijun Shen Dr. Brandon Taylor Anwesh Kamireddy Dr. George Harb Dr. Jing Li Dr. Yong Jia Dr. Andrew M. Schumacher Dr. Bryan Laffitte Dr. Richard Glynne Dr. Shifeng Pan Dr. Peter McNamara Dr. Valentina Molteni Dr. Jon Loren 《ChemMedChem》2020,15(16):1562-1570
Loss of β-cell mass and function can lead to insufficient insulin levels and ultimately to hyperglycemia and diabetes mellitus. The mainstream treatment approach involves regulation of insulin levels; however, approaches intended to increase β-cell mass are less developed. Promoting β-cell proliferation with low-molecular-weight inhibitors of dual-specificity tyrosine-regulated kinase 1A (DYRK1A) offers the potential to treat diabetes with oral therapies by restoring β-cell mass, insulin content and glycemic control. GNF4877, a potent dual inhibitor of DYRK1A and glycogen synthase kinase 3β (GSK3β) was previously reported to induce primary human β-cell proliferation in vitro and in vivo. Herein, we describe the lead optimization that lead to the identification of GNF4877 from an aminopyrazine hit identified in a phenotypic high-throughput screening campaign measuring β-cell proliferation. 相似文献
4.
5.
McIntyre Christa K.; Marriott Lisa K.; Gold Paul E. 《Canadian Metallurgical Quarterly》2003,117(2):320
The present experiment examined the relationship between release of acetylcholine (ACh) in the amygdala and performance on a hippocampus-dependent spatial working memory task. Using in vivo microdialysis, the authors measured ACh release in rats during testing on a spontaneous alternation task. Amygdala ACh release was positively correlated with performance on the hippocampus-dependent task. These findings suggest that activation of the amygdala promotes processing in other neural systems important for learning and memory. (PsycINFO Database Record (c) 2010 APA, all rights reserved) 相似文献
6.
We could not imagine a more appropriate inauguration of the Psychology of Aesthetics, Creativity, and the Arts (PACA) going to four issues per year than with a special issue honoring the life and work of the great aesthetician and psychologist, Rudolf Arnheim. PACA is off to a great start. With this move to four issues per year, we are restarting our numbering system, so this special issue is Volume 1, Issue 1. As you read the articles in this issue, we hope that you enjoy reflecting on how much Rudolf Arnheim has contributed to the field of psychology of aesthetics. (PsycINFO Database Record (c) 2010 APA, all rights reserved) 相似文献
7.
Ö. Jonsson T. Larsson M. Rönnqvist 《Structural and Multidisciplinary Optimization》1994,7(1-2):103-111
An efficient and commonly used approach to structural optimization is to solve a sequence of approximate design problems that are constructed iteratively. As is well-known, a major part of the computational burden of this scheme lies in the sensitivity analysis needed to state the approximate problems. We propose a possibility for reducing this burden by streamlining the calculations in a combined approximation and duality scheme for structural optimization. The difference between this scheme and the traditional one is that, instead of calculating all the constraint gradients to state an approximate design problem explicitly, linear combinations of these gradients are generated as they are needed during the solution of the approximate problem by the dual method. We show, by analysing some typical scenarios of problem characteristics, that this rearrangement of the calculations may be a computationally viable alternative to the traditional scheme. An advantage of streamlining the calculations is that there is no need to incorporate an active set strategy in the scheme, as is usually done, since all the design constraints may be taken into consideration without any loss of computational efficiency. This may, clearly, enhance the practical rate of convergence of the overall approximation scheme. Moreover, the proposed rearrangement of the calculations may make it computationally viable to apply iterative equation solvers to the structural analysis problem. Numerical results with direct as well as iterative equation solvers show that the streamlined scheme is a feasible and promising approach to structural optimization. 相似文献
8.
In a conceptual replication of A. Biglan et al (see record 1989-39898-001), 288 Ss rated their emotional and behavioral responses to aggressive, distressed, and neutral behaviors. The stimulus behaviors occurred in the context of casual relationships and were portrayed by male and female actors. Consistent with Biglan et al, it was found that aggressive behaviors evoked angry emotions and negative behavioral responses; distressed behaviors evoked both angry and concerned emotions and supportive behavioral responses. However, in contrast to the original results, evidence was also found of negative (primarily avoidant) behavioral responses to distressed behavior. (PsycINFO Database Record (c) 2010 APA, all rights reserved) 相似文献
9.
AP Christiansen B Wanscher HB Larsson O Henriksen 《Canadian Metallurgical Quarterly》1994,156(43):6348-6352
Multiple sclerosis is a chronic demyelinating disease. Paraclinical examinations may contribute to the diagnosis of multiple sclerosis. Magnetic resonance imaging (MRI) has a very high sensitivity concerning multiple sclerosis, and has made it possible to visualize multiple sclerosis plaques in vivo, to follow each plaque over the course of time and in this way to obtain information about the pathogenesis. MRI has shown that the size of plaques may vary considerably, and that plaques are dynamic structures with the ability to change in size over few weeks. By using MRI and the contrast agent Gadolinium-DTPA, it is possible to distinguish a newly developed plaque from an older one. Therefore, MRI has become an important examination in therapeutic trials. Just now, MRI with Gadolinium-DTPA is being used to evaluate the efficacy of plasmapheresis and immunoglobulin treatment in a joint study between Rigshospitalet and Hvidovre Hospital. 相似文献
10.
This study evaluates the impact assessment methodologies used by Uganda's Water Hyacinth Control Programme in Lake Victoria, a domestic project with transboundary implications. The Control Programme sought to reduce infestations of water hyacinth (Eichhornia crassipes), an aquatic weed native to South America, through the use of integrated chemical, mechanical and biological methods. The environmental impact assessment for the project was conducted by Aquatics Unlimited, with support from the United States Agency for International Development. Although the case study involves a domestic impact assessment, it raised transboundary concerns. One of the major outcomes of the assessment was recognition of the need for informed involvement of the other riparian countries, Kenya and Tanzania, in the assessment process to ensure a regional effort among all three East African Community Partner States to control water hyacinth and other invasive weeds in Lake Victoria. 相似文献