Bilateral arachnoid cysts, seizures and severe encephalopathy: case report

A case is presented of a 3 1/2-year-old girl with a clinical picture of very severe psychomotor retardation, autistic behavior, and repetitive convulsive episodes starting in the neonatal period and resistant to any pharmacological treatment. Electroencephalography showed generalized abnormalities. Magnetic resonance imaging of the brain disclosed arachnoid cysts in both temporal fossae with marked hypoplasia of both temporal lobes. It is proposed that the severity of symptoms is related to the magnitude of underlying anatomical lesions as well as the associated intractable epilepsy.     

火电机组运行优化系统的现状与展望

简单回顾了国内外在火电机组运行优化领域的研究历程，列举了目前国内外市场上针对火电机组的各种主流运行优化产品的功能特点和应用情况，分析了国外引进产品和国内自主研发产品在中国当前市场环境下各自的优势和劣势。介绍了当前运行优化系统在国内电站机组的应用现状，阐述了国内外运行优化系统在实际应用中存在的问题，并提出了相应的改进意见。对机组运行优化系统的未来发展进行了展望，指出机组运行优化系统将利用先进技术设备和信息平台，与电站管理紧密结合，在日益规范的市场中不断发展完善，为提高电站经济性发挥更大的作用。     

The effect of unilateral destruction of the head of the caudate nucleus with kainic acid on the structure of the wakefulness-sleep cycle and the EEG in rats

The wakefulness-sleep cycle characteristics changes in Wistar line rats after unilateral lesions of the neuronal elements of the caudate nucleus head with kainic acid (at sparing the conducting ways going through this structure) were studied. It was shown that in 4 days after acid injection the share of the active wakefulness and light slow-wave sleep is significantly increased, whereas the percentage of the passive wakefulness, deep slow-wave stage, and paradoxal sleep (up to 80%) is reduced. The wakefulness-sleep cycle in rats is completely normalized on the 7th day after injection. The obtained data allow to consider the caudate nucleus as a modulator for wakefulness-sleep cycle, that is the structure involved in the motive activity regulation.     

Cdc34 and the F-box protein Met30 are required for degradation of the Cdk-inhibitory kinase Swe1

Ubiquitin-mediated proteolysis controls the abundance of many cell cycle regulatory proteins. Recent work in Saccharomyces cerevisiae suggests that a complex consisting of Cdc53, Skp1, and a third component known as an F-box protein (termed SCF) in combination with Cdc34 specifically targets regulatory proteins for degradation, and that substrate specificity is likely to be mediated by the F-box subunit. A screen for genetic interactions with a cdc34 mutation yielded MET30, which encodes an F-box protein. MET30 is an essential gene required for cell cycle progression and met30 mutations interact genetically with mutations in SCF components. Furthermore, physical interactions between Met30, Cdc53, Cdc34, and Skp1 in vivo provide evidence for an SCFMet30 complex. We demonstrate the involvement of Met30 in the degradation of the Cdk-inhibitory kinase Swe1. Swe1 is stabilized in met30 mutants and GST-Met30 pull-down experiments reveal that Met30 specifically binds Swe1 in vivo. Furthermore, extracts prepared from cdc34 or met30 mutants are defective in polyubiquitination of Swe1. Taken together, these data suggest that SCF-mediated proteolysis may contribute to the regulation of entry into mitosis. Our data, in combination with previously published results, also provide evidence for distinct SCF complexes in vivo and support the idea that their F-box subunits mediate SCF substrate specificity.     

基于互联网实现多种信息传输技术

随着信息技术的迅速发展,使用互联网实现楼宇内电话、电视、电脑、安防和环境监控、计量数据等信息的合路传输,是实现智能家居和数字楼宇的一种主要发展趋势。最终目的,实现对物和过程的智能化感知。文章首先介绍信息合路编码、中央控管电路,然后介绍网络接口电路原理和系统体系构架。重点介绍多种多样的信息传输技术。它对现代楼宇信息化、智能化建设有很好的参考作用。     

辣椒疫病菌对氟吗啉的抗药性研究

为了评估氟吗啉的未来抗性风险，以辣椒疫病菌为靶标，通过室内抗性菌株的驯化、筛选，以及紫外线诱变等方法，初步探索了辣椒疫病菌对氟吗啉的抗性情况。结果表明：抗性菌株对氟吗啉的抗性倍数较低，在3.45～11．33，生长速率明显低于野生敏感菌株。由此可见辣椒疫病菌对氟吗啉的抗性风险可能较低。     

MIMO系统非线性模糊免疫PID的设计与优化

针对工业中常规控制器难以达到较好控制效果的控制难点,提出了免疫PID控制器,利用模糊控制可以无限逼近非线性的特性,构成非线性模糊免疫PID控制器,并基于正交函数将M1MO(多输入多输出)控制系统的非线性模糊免疫PID控制器的设计过程转化为由一个只含有代数方程的算法来实现,最后用具有自适应功能的遗传算法对其进行优化.仿真结果表明,所设计的控制器在控制性能上优于常规PID,并能快速得到最优参数.另方面对于多输入多输出控制系统,控制器的设计和优化显得更为简便和有效.     

医院超声图象管理系统的设计与实现

介绍了医院超声图象管理系统的功能和特点,并阐述了其关键技术。