Evaluation of the effect of processing on cocoa polyphenols: antiradical activity,anthocyanins and procyanidins profiling from raw beans to chocolate

The content and composition of anthocyanins and procyanidins in fermented cocoa beans (from different geographic origins: Ecuador, Cameroon, Ivory Coast, Ghana and Nigeria), roasted nibs, cocoa mass and chocolate were determined, beside the determination of the total antiradical capacity. Concerning geographic origin, cocoa beans and processed products from Ecuador showed the highest levels of anthocyanins, followed by Nigeria and Cameroon. Generally, as cocoa beans were further processed, the levels of anthocyanins and flavan‐3‐ols decreased. The largest observed losses of phenolics occurred during roasting. A progressive decreasing trend in polyphenol concentration was observed in the other processed samples as well. Despite the original content of polyphenols in raw cocoa beans, technological processes imply a significant impact on cocoa quality, confirming the need of specific optimisation to obtain high value chocolate.     

令客户满意的五条法则及为何其重要性往往被过分夸大

根据哈佛商学院最著名的教授MichaelPorte r的观点:"运营效率意味着你能在一场赛跑中跑得更快,而战略却能帮你选择一场能最终获胜的赛跑."(引自"Michael Porte r归来",<财富>1999年2月刊.)现今,客户满意度--令客户喜欢你的产品及服务的程度,取决于企业的运营效率.因此,将企业比作一艘船,如果船即将撞上冰山,即使你能令乘客满意到最后,但却不能避免整艘船的沉没.要想成功绕开冰山,你只有想出优于对手的战略.     

Clarification of a wheat straw‐derived medium with ion‐exchange resins for xylitol crystallization

BACKGROUND: Xylitol bioproduction from lignocellulosic residues comprises hydrolysis of the hemicellulose, detoxification of the hydrolysate, bioconversion of the xylose, and recovery of xylitol from the fermented hydrolysate. There are relatively few reports on xylitol recovery from fermented media. In the present study, ion‐exchange resins were used to clarify a fermented wheat straw hemicellulosic hydrolysate, which was then vacuum‐concentrated and submitted to cooling in the presence of ethanol for xylitol crystallization. RESULTS: Sequential adsorption into two anion‐exchange resins (A‐860S and A‐500PS) promoted considerable reductions in the content of soluble by‐products (up to 97.5%) and in medium coloration (99.5%). Vacuum concentration led to a dark‐colored viscous solution that inhibited xylitol crystallization. This inhibition could be overcome by mixing the concentrated medium with a commercial xylitol solution. Such a strategy led to xylitol crystals with up to 95.9% purity. The crystallization yield (43.5%) was close to that observed when using commercial xylitol solution (51.4%). CONCLUSION: The experimental data demonstrate the feasibility of using ion‐exchange resins followed by cooling in the presence of ethanol as a strategy to promote the fast recovery and purification of xylitol from hemicellulose‐derived fermentation media. Copyright © 2008 Society of Chemical Industry     

Efficient compensation for frequency-dependent errors in analog reconstruction filters used in IQ modulators

In a direct-conversion transmitter system, the nonideal transfer characteristics of practical analog subsystems can have significant adverse effects on the performance of the transmitter system. While a significant body of research exists on correcting static errors (including gain imbalance, phase errors, and DC offsets) in the analog subsystems, relatively little attention has been paid to the impact of nonideal frequency-dependent characteristics in the analog reconstruction filters that are employed in direct-conversion structures. This paper presents a new computationally efficient and numerically robust method for automatic digital compensation for nonideal frequency-dependent characteristics in the signal reconstruction filters of a quadrature (IQ) modulator structure. The new compensation technique is used in conjunction with existing compensation approaches that compensate for static errors.     

Fast Full-Band Device Simulator for Wurtzite and Zincblende GaN MESFET Using a Cellular Monte Carlo Method

A fast full-band device simulator for wurtzite and zincblende GaN using a Cellular Monte Carlo (CMC) approach is reported for wurtzite and zincblende GaN. The full-phonon dispersion relationship including anisotropic polar-optical phonon scattering is taken into account for the wurtzite GaN calculation. In the bulk simulation, the CMC model is about 30–100 times faster than the conventional Ensemble Monte Carlo model at high electric field region. This CMC model is applied to the simulator of MESFET devices, and the calculation speed is significantly improved.     

Interobl: An interactive software tool for displaying and scaling oblique ionograms

By analyzing an oblique ionogram several characteristics, such as LOF, MOF, FMUF, FHLOF, FLLOF, and 2FMOF, can be found. These characteristics are important both for ionospheric studies and for terrestrial communication purposes, as they give information about the sky wave communication conditions in the High Frequency (HF) radio spectrum.A RCS-5B sweeping HF receiver for oblique sounding was installed at Chania (Crete, Greece, 35.7°N, 24.0°E) in April 2005 to perform a radio link with Inskip (UK, 53.5°N, 2.5°W). The receiver, able to record the sounding only as a binary file, was not equipped with a tool to display and scale the recorded trace. This work describes software that is able to do this, consequently increasing the speed of the scaling phase performed by the operator. The usefulness of this software for validating FMUF prediction models is also shown.     

The natural killer cell receptor specific for HLA-A allotypes: a novel member of the p58/p70 family of inhibitory receptors that is characterized by three immunoglobulin-like domains and is expressed as a 140-kD disulphide-linked dimer

Human natural killer (NK) cells express inhibitory receptors that are specific for different groups of HLA-C or HLA-B alleles. The majority of these receptors belong to the immunoglobulin (Ig) superfamily and are characterized by two or three extracellular Ig-like domains. Here we describe a novel inhibitory NK receptor that is specific for a group of HLA-A alleles. The HLA-A3-specific NK cell clone DP7 has been used for mice immunization. Two mAbs, termed Q66 and Q241, bound to the immunizing clone and stained only a subset of NK cell populations or clones. Among Q66 mAb-reactive clones, we further selected those that did not express any of the previously identified HLA-class I-specific NK receptors. These clones did not lyse HLA-A3+ (or -A11+) target cells, but lysis of these targets could be detected in the presence of Q66 or Q241 mAbs. On the other hand, target cells expressing other HLA-A alleles, including -A1, -A2, and -A24, were efficiently lysed. Moreover, none of the HLA-C or HLA-B alleles that were tested exerted a protective effect. Q66+, but not Q66- NK cell clones, expressed messenger RNA coding for a novel 3 Ig domain protein homologous to the HLA-C (p58) and HLA-B (p70) receptors. The corresponding cDNA (cl.1.1) was used to generate transient and stable transfectants in COS7 and NIH3T3 cell lines, respectively. Both types of transfectants were specifically stained by Q66 and Q241 mAbs. Since the cytoplasmic tail of Q66-reactive molecules was at least 11 amino acid longer than the other known p58/p70 molecules, we could generate an antiserum specific for the COOH-terminus of Q66-reactive molecules, termed PGP-3. PGP-3 immunoprecipitated, only from Q66+ NK cells, molecules displaying a molecular mass of 140 kD, under nonreducing conditions, which resolved, under reducing conditions, in a 70-kD band. Thus, differently from the other p58/p70 receptors, Q66-reactive molecules appear to be expressed as disulphide-linked dimers and were thus termed p140. The comparative analysis of the amino acid sequences of p58, p70, and p140 molecules revealed the existence of two cysteins proximal to the transmembrane region, only in the amino acid sequence of p140 molecules.     

Nonlinear Creep Damage Model for Concrete under Uniaxial Compression

An isotropic model for creep damage of concrete under uniaxial compression is proposed, where the combined effect of nonlinear viscous strain evolution and crack nucleation and propagation at high stress levels is considered. Strain splitting assumption is used for creep and damage contributions. Creep is modeled by a modified version of solidification theory. As usual in the modeling of damage of concrete, a damage index based on positive strains is introduced. As particular cases, the proposed model reduces to linear viscoelasticity for long time low stress levels whereas, for very high stresses, tertiary creep causing failure at a finite time can be described. The effect of strength variation with time is also included. The model is numerically implemented to perform time integration of nonlinear equations by means of a modified version of exponential algorithm. The model is validated through comparison with experimental results. Some numerical examples are also presented, where the roles of concrete ageing and strength variation with time are investigated.