The solution of radiation engineering problems on a transputer-based system

Monte Carlo and finite element methods are numerical techniques used for solving complex problems in reactor physics and radiation shielding. In this paper we are concerned with the implementation of existing research-level codes based on these two methods, written originally for serial computers, on an MIMD transputer-based system. Results and performance of the parallelized codes are presented.     

Monte Carlo photon transport on parallel computers

In this paper we consider the implementation of particle tracking Monte Carlo on two different types of parallel computer architectures, namely, (i) the AMT DAP-610 array of processors which is a SIMD machine and (ii) the transputer based Meiko Computing Surface which is a MIMD machine. An analogue, research-level, fixed source, particle transport Monte Carlo code for studying the attenuation and leakage of gamma ray photons in simple, multilayer, shielding configurations, originally written for serial computers, is modified and re-written to run efficiently on these two different types of parallel machine. The philosophy adopted and algorithms developed in transferring the code to the parallel machines are described. Two illustrative problems are solved using realistic cross-section data, involving a 9 MeV source of gamma photons in a lead-void-water sphere and slab. Integral quantities, such as fraction of particles absorbed and escaped, and differential quantities, such as flux distributions and leakage spectra, computed by the parallel codes, are presented in tables and graphs. For equivalent calculations, the CPU times on the DAP and a number of serial computers (e.g. ICL-3900, CRAY XMP/28 in scalar mode, SUN 4, and VAX 11/750) are compared, and the resulting speedup factors quoted. For the Meiko Computing Surface, the performance obtained from running the code when the number of transputers used is varied, is tabulated. Finally, the performance of the two parallel machines is compared.     

Multi-Gbit/s 60 GHz Transceiver Analysis Using FDM Architecture and Six-Port Circuit

This paper presents an analysis and validation by advanced system simulation of compact and low-cost six-port transceivers for future wireless local area networks （WLANs） operating at millimeter-wave frequencies. To obtain realistic simulation results, a six-port model based on the measurement results of a fabricated V-band hybrid coupler, the core component, is used. A frequency-division multiplexing scheme is used by introducing four quadrature phase-shift keying （QPSK） channels in the wireless communication link. The data rate achieved is about 4 Gbit/s. The operating frequency is in the 60-64 GHz unlicensed band. Bit error rate （BER） results are presented, and a comparison is made between single-carrier and multicarrier architectures. The proposed wireless system can be considered an efficient candidate for millimeter-wave communication systems operating at quasi-optical data rates.     

Structurally different anthracyclines provoke different effects on cell cycle and tumor B cell differentiation

Previously we have detected a stimulatory effect on immunoglobulin (IgG) synthesis when hybridoma cells were treated with doxorubicin. In order to determine whether this is a general property of anthracycline, we have selected three analogs--doxorubicin (DOX), pirarubicin (THP-DOX) and aclarubicin (ACR)--which differ mainly in the methylation state of their amino sugars. Cell cycle analysis by flow cytometry and drug localization by scanning confocal microscopy were also performed. The results show that when cells (UN2 hybridoma B cells), were exposed to subtoxic doses of DOX or THP (with unmethylated amino sugars), a strong increases in IgG secretion, heavy (H) and light (L) chain synthesis and the corresponding mRNA levels were induced. Furthermore these two drugs arrested the cells in the G2/M phase of the cell cycle. In contrast, exposure to ACR (with its methylated amino sugar) at similar subtoxic doses induced a blockade of cells in the G1 phase with no increase of IgG synthesis, at the subtoxic doses used, all three drugs could still be detected in the nucleus as well as in the cytoplasm, as determined by confocal laser microscopy. Thus, the relationship between cell cycle blockade, IgG stimulation and anthracycline structure is suggested by these results.     

Mineralocorticoid hormone receptor and the epithelial sodium channel in a human leukemic cell line

A Cell extract from the HEL (human erythroblastic leukemia) cell line was positive for both the epithelial sodium channel (ENaC) and the mineralocorticoid receptor (MCR) as glycosylated 82-84 kDa bands, and a single 102 kDa band, respectively, in Western blots using polyclonal antibodies raised against these proteins. The immunofluorescent labeling of the MCR in all cell lines showed a nucleocytoplasmic localization of the receptor whereas the ENaC was exclusively membrane-bound. These results were confirmed by confocal microscopy. The expression of the MCR in HEL cells was evident as a predicted band of 843 bp (234 amino acids) after total RNA from HEL cells had been reverse transcribed and then amplified by PCR; the ENaC was similarly evident as a predicted band of 520 bp. In both cases, near 100% identity was observed between the deduced amino acid sequences of the PCR products and those from known human sources. The multiplication of HEL cells was influenced by antagonists (RU 26752, ZK 91587) targeted for specificity to the MCR and this was reversed by the natural hormone aldosterone. These steroids also provoked chromatin condensation in the HEL population.     

A Stretchable and Flexible Cardiac Tissue–Electronics Hybrid Enabling Multiple Drug Release,Sensing, and Stimulation

Replacement of the damaged scar tissue created by a myocardial infarction is the goal of cardiac tissue engineering. However, once the implanted tissue is in place, monitoring its function is difficult and involves indirect methods, while intervention necessarily requires an invasive procedure and available medical attention. To overcome this, methods of integrating electronic components into engineered tissues have been recently presented. These allow for remote monitoring of tissue function as well as intervention through stimulation and controlled drug release. Here, an improved hybrid microelectronic tissue construct capable of withstanding the dynamic environment of the beating heart without compromising electronic or mechanical functionality is reported. While the reported system is enabled to sense the function of the engineered tissue and provide stimulation for pacing, an electroactive polymer on the electronics enables it to release multiple drugs in parallel. It is envisioned that the integration of microelectronic devices into engineered tissues will provide a better way to monitor patient health from afar, as well as provide facile, more exact methods to control the healing process.     

Status,ecological services and management of aquatic weeds of floodplain wetlands in India: An overview

Floodplain wetlands of India are biologically rich and productive ecosystems that support unique aquatic flora and fauna. Covering an area of about 0.354 million ha, the floodplain wetlands are a major source of self‐recruiting small indigenous fish (SIF). They offer vast potential for both capture and culture‐based fisheries, securing livelihood and nutrition for a large section of the population. In addition to tremendous anthropogenic pressures and climatic variability, these resources have experienced a significant reduction in their geographical and areal extent. Aquatic macrophytes infestation in Indian floodplain wetlands is posing serious challenges to their ecological and economic functioning. Degradation and shrinkage of these important resources have been observed over the past few decades, attributable to the spread of aquatic weed infestation, warranting urgent attention in regard to their conservation and restoration to address their impending challenges. The present study compiled a total of 530 species under 103 families of aquatic macrophyte, representing four Indian states of the Ganga and Brahmaputra river basin. Among these 530 species, 85 species exhibit medicinal values and 30 species are edible, whereas some other species are used for basketry, cordage, fodder and as dye. Accordingly, the present study reviews the present status of the floodplain wetlands, their common aquatic weeds and their ecological services. It also synthesizes the latest knowledge and discusses the challenging issues of aquatic weed management and their control measures directed to the sustainable management of the aquatic resources.     

Hydrothermal Synthesis of Aluminum Terephthalate

A process is described for the synthesis of aluminum terephthalate by autoclaving a suspension of terephthalic acid in an aluminum chloride solution at temperatures from 150 to 390°C and pressures from 2 to 20 MPa. The conditions ensuring the maximum yield of aluminum terephthalate are established. The composition of the reaction product is determined to be Al₂[C₆H₄(COO)₂]₃ ? 2H₂O. The effect of the liner material on the reaction between terephthalic acid and aluminum chloride solutions is analyzed. It is shown that the final product of aluminum terephthalate decomposition during heating in air to 950°C is γ-Al₂O₃.     

Distributed Air-Conditioning Energy Management System within the Smart Grid Context

Air-conditioning(AC) systems are the major energy consumption units in residential and commercial buildings. In the context of smart grid, optimizing AC operations leads to substantial saving in energy consumption, reducing the consumer’s bill and contributing to the environment by minimizing carbon emissions from generating stations. This paper presents a distributed AC energy management system for buildings by using networked master-slaves controller architecture. The proposed system was designed, simulated, and experimentally tested by using real AC units in a students’ residence hall. Based on the students’ class schedules, several operational scenarios were implemented and tested. The proposed system implementation leads to a 40% to 60% saving of the consumed energy by the tested units. The same energy management scheme can be applied and implemented in other commercial and residential buildings.