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Malgorzata Kloc Ahmed Uosef Jacek Z. Kubiak Rafik Mark Ghobrial 《International journal of molecular sciences》2021,22(1)
The development, progression, or stabilization of the atherosclerotic plaque depends on the pro-inflammatory and anti-inflammatory macrophages. The influx of the macrophages and the regulation of macrophage phenotype, inflammatory or anti-inflammatory, are controlled by the small GTPase RhoA and its downstream effectors. Therefore, macrophages and the components of the RhoA pathway are attractive targets for anti-atherosclerotic therapies, which would inhibit macrophage influx and inflammatory phenotype, maintain an anti-inflammatory environment, and promote tissue remodeling and repair. Here, we discuss the recent findings on the role of macrophages and RhoA pathway in the atherosclerotic plaque formation and resolution and the novel therapeutic approaches. 相似文献
3.
Abdelaziz Lakhfif Mohamed Tayeb Laskri 《International Journal of Speech Technology》2016,19(2):203-228
This paper describes the design and implementation of a computational model for Arabic natural language semantics, a semantic parser for capturing the deep semantic representation of Arabic text. The parser represents a major part of an Interlingua-based machine translation system for translating Arabic text into Sign Language. The parser follows a frame-based analysis to capture the overall meaning of Arabic text into a formal representation suitable for NLP applications that need for deep semantics representation, such as language generation and machine translation. We will show the representational power of this theory for the semantic analysis of texts in Arabic, a language which differs substantially from English in several ways. We will also show that the integration of WordNet and FrameNet in a single unified knowledge resource can improve disambiguation accuracy. Furthermore, we will propose a rule based algorithm to generate an equivalent Arabic FrameNet, using a lexical resource alignment of FrameNet1.3 LUs and WordNet3.0 synsets for English Language. A pilot study of motion and location verbs was carried out in order to test our system. Our corpus is made up of more than 2000 Arabic sentences in the domain of motion events collected from Algerian first level educational Arabic books and other relevant Arabic corpora. 相似文献
4.
Diab Tayeb Gilg Marc Lorenz Pascal Drouhin Frederic 《Wireless Personal Communications》2022,127(3):2625-2644
Wireless Personal Communications - The Invisible Internet Project (I2P) as a secure protocol uses robust mechanisms and strong algorithms to reinforce the security and the anonymity of the... 相似文献
5.
Menghao Qin Rafik Belarbi Abdelkarim Aït-Mokhtar Lars-Olof Nilsson 《Construction and Building Materials》2009,23(2):967-975
A dynamic mathematical model for simulating the coupled heat and moisture migration through multi-layer porous building materials was proposed. Vapor content and temperature were chosen as the principal driving potentials. The discretization of the governing equations was done by the finite difference approach. A new experimental set-up was also developed in this study. The evolution of transient temperature and moisture distributions inside specimens were measured. The method for determining the temperature gradient coefficient was also presented. The moisture diffusion coefficient, temperature gradient coefficient, sorption–desorption isotherms were experimentally evaluated for some building materials (sandstone and lime-cement mortar). The model was validated by comparing with the experimental data with good agreement. Another advantage of the method lies in the fact that the required transport properties for predicting the non-isothermal moisture flow only contain the vapor diffusion coefficient and temperature gradient coefficient. They are relatively simple, and can be easily determined. 相似文献
6.
In this article, a new ultra‐wideband rectangular‐slot antenna is proposed and developed for multiband wireless communication systems. The radiating slot is fed by a microstrip line with a microstrip fork‐shaped tuning stub. The frequency characteristic and radiation performance of the proposed antenna are successfully optimized, and a prototype is fabricated and tested. The measured results show that the impedance bandwidth can cover the band from 1.85 to 6.1 GHz with return loss of better than 10 dB, and the corresponding radiation displays omnidirectional patterns across the interested bands. With these frequencies, the proposed structure is especially suitable for applications in wireless communication systems, where a single antenna is needed to operate simultaneously at different bands, such as PCS (1.85–1.99 GHz), UMTS (1.92–2.17 GHz) and all WLAN bands (2.4–2.48 GHz and IEEE802.11a WLAN applications at 5.15–5.35 GHz and 5.725–5.825 GHz). © 2006 Wiley Periodicals, Inc. Int J RF and Microwave CAE, 2006. 相似文献
7.
Bacterial-based additives for the production of artificial snow: What are the risks to human health?
Arnaud Lagriffoul Rafik Absi Jean-Marc Berjeaud Edmond E. Creppy Jean-Pierre Gadonna Cindy E. Morris 《The Science of the total environment》2010,408(7):1659-1666
For around two decades, artificial snow has been used by numerous winter sports resorts to ensure good snow cover at low altitude areas or more generally, to lengthen the skiing season. Biological additives derived from certain bacteria are regularly used to make artificial snow. However, the use of these additives has raised doubts concerning the potential impact on human health and the environment. In this context, the French health authorities have requested the French Agency for Environmental and Occupational Health Safety (Afsset) to assess the health risks resulting from the use of such additives. The health risk assessment was based on a review of the scientific literature, supplemented by professional consultations and expertise. Biological or chemical hazards from additives derived from the ice nucleation active bacterium Pseudomonas syringae were characterised. Potential health hazards to humans were considered in terms of infectious, toxic and allergenic capacities with respect to human populations liable to be exposed and the means of possible exposure. Taking into account these data, a qualitative risk assessment was carried out, according to four exposure scenarios, involving the different populations exposed, and the conditions and routes of exposure. It was concluded that certain health risks can exist for specific categories of professional workers (mainly snowmakers during additive mixing and dilution tank cleaning steps, with risks estimated to be negligible to low if workers comply with safety precautions). P. syringae does not present any pathogenic capacity to humans and that the level of its endotoxins found in artificial snow do not represent a danger beyond that of exposure to P. syringae endotoxins naturally present in snow. However, the risk of possible allergy in some particularly sensitive individuals cannot be excluded. Another important conclusion of this study concerns use of poor microbiological water quality to make artificial snow. 相似文献
8.
Hasnia Benmoussa Asma Farhat Rafik Bachoual Zina Nasfi Mehrez Romdhane 《分离科学与技术》2016,51(13):2145-2152
The present study aims to compare two innovative extraction techniques: microwave-assisted hydrodistillation (MAHD) and solvent-free microwave extraction (SFME) through traditional extraction techniques: hydrodistillation (HD) and steam distillation (SD) for their efficiency in the extraction of the volatile compounds from Tunisian Thymus vulgaris leaves; the kinetic, yield, composition and antibacterial activities of the essential oil were assessed in vitro. Results show that the essential oils extracted by microwaves were quantitatively (yield) similar to those obtained through the conventional methods, but qualitatively, essential oils analysed by gas chromatography–mass spectrometry (GC–MS) presented 17, 11, 11 and 8 compounds obtained through SFME, MAHD, SD and HD, respectively, mostly consisting of carvacrol (89.24–41.17%), followed by γ-terpinene (11.37–1.37%) and para-cymene (27.95–2.05%). The essential oils were screened for antibacterial activity against 5 microorganisms. All essential oils obtained by studied extraction methods showed the same resistance against Gram (?) and Gram (+) bacteria. The SFME method gave the best results: rapid kinetic of extraction (30 min vs. 35 min for MAHD, 120 min for SD, and 180 min for HD), less energy saving and cleanest process. 相似文献
9.
Generating a Condensed Representation for Association Rules 总被引:1,自引:0,他引:1
Nicolas?PasquierEmail author Rafik?Taouil Yves?Bastide Gerd?Stumme Lotfi?Lakhal 《Journal of Intelligent Information Systems》2005,24(1):29-60
Association rule extraction from operational datasets often produces several tens of thousands, and even millions, of association rules. Moreover, many of these rules are redundant and thus useless. Using a semantic based on the closure of the Galois connection, we define a condensed representation for association rules. This representation is characterized by frequent closed itemsets and their generators. It contains the non-redundant association rules having minimal antecedent and maximal consequent, called min-max association rules. We think that these rules are the most relevant since they are the most general non-redundant association rules. Furthermore, this representation is a basis, i.e., a generating set for all association rules, their supports and their confidences, and all of them can be retrieved needless accessing the data. We introduce algorithms for extracting this basis and for reconstructing all association rules. Results of experiments carried out on real datasets show the usefulness of this approach. In order to generate this basis when an algorithm for extracting frequent itemsets—such as Apriori for instance—is used, we also present an algorithm for deriving frequent closed itemsets and their generators from frequent itemsets without using the dataset. 相似文献
10.
Over-exploitation of the groundwater resources is the major problem leading to groundwater depletion in the Sa'dah Plain, one of the major semi-arid highland basins of Yemen. Groundwater-irrigated agriculture is the chief economic activity in the Plain. Consequently, depletion places socioeconomic development in jeopardy. Owing to the lack of institutional arrangements and management instruments, government intervention is not likely to alleviate the crisis. One non-governmental approach that takes advantage of the existing local sociopolitical structure and customary law would be to adopt an annual abstraction quota. Approaching the crisis at a grass-roots level and relying on the conformity of the local citizens with customary law are the main characteristics of this strategy, the optimum objective of which is sustainable utilization of water resources. 相似文献