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1.
An experimental study of heat transfer to boiling liquids under natural convective flow has been carried out in a single tube vertical thermosiphon reboiler to investigate the effect of heat flux and submergence on circulation rates. The test liquids used were distilled water, various concentrations of propan-2-ol in water and their azeotrope. The test section was an electrically heated stainless steel tube of 25.56 mm i.d., 28.85 mm o.d. and 1900 mm long with twenty-one spot welded copper constantan thermocouples to measure the variations in wall temperature along its axis. The uniform heat fluxes in the range of 3.5–42.4 kW/m2 were employed while inlet liquid sub-cooling varied from 0.2 to 30.7 °C. The liquid submergence levels were maintained in the range 30–100%. The typical experimental data has been graphically presented and discussed. An empirical correlation has been developed from the experimental data of the present study through regression analysis.  相似文献   
2.
The Internet Archive’s (IA) Wayback Machine is the largest and oldest public Web archive and has become a significant repository of our recent history and cultural heritage. Despite its importance, there has been little research about how it is discovered and used. Based on Web access logs, we analyze what users are looking for, why they come to IA, where they come from, and how pages link to IA. We find that users request English pages the most, followed by the European languages. Most human users come to Web archives because they do not find the requested pages on the live Web. About 65 % of the requested archived pages no longer exist on the live Web. We find that more than 82 % of human sessions connect to the Wayback Machine via referrals from other Web sites, while only 15 % of robots have referrers. Most of the links (86 %) from Websites are to individual archived pages at specific points in time, and of those 83 % no longer exist on the live Web. Finally, we find that users who come from search engines browse more pages than users who come from external Web sites.  相似文献   
3.
Designing efficient as well as secure cryptographic protocols for resource-constrained applications is a challenging task. In this paper, we formally analyze the security of an efficient one-pass authenticated key establishment protocol, the 1P-AKE protocol, which is primarily proposed for resource-constrained sensor nodes devices in wireless sensor networks (WSNs). In contrast to the existing identity-based one-pass key establishment protocols, the 1P-AKE protocol does not require any bilinear pairing computation in order to establish a key. This feature makes it really attractive for resource-constrained application environments, such as WSNs, where pairing computations are too expensive. We show that in the random oracle model, the 1P-AKE protocol is a secure authenticated one-pass key establishment protocol under the computational Diffie–Hellman assumption. The performance of the 1P-AKE protocol is also discussed and compared with the existing relevant protocols.  相似文献   
4.
Web archives have become a significant repository of our recent history and cultural heritage. Archival integrity and accuracy is a precondition for future cultural research. Currently, there are no quantitative or content-based tools that allow archivists to judge the quality of the Web archive captures. In this paper, we address the problems of detecting when a particular page in a Web archive collection has gone off-topic relative to its first archived copy. We do not delete off-topic pages (they remain part of the collection), but they are flagged as off-topic so they can be excluded for consideration for downstream services, such as collection summarization and thumbnail generation. We propose different methods (cosine similarity, Jaccard similarity, intersection of the 20 most frequent terms, Web-based kernel function, and the change in size using the number of words and content length) to detect when a page has gone off-topic. Those predicted off-topic pages will be presented to the collection’s curator for possible elimination from the collection or cessation of crawling. We created a gold standard data set from three Archive-It collections to evaluate the proposed methods at different thresholds. We found that combining cosine similarity at threshold 0.10 and change in size using word count at threshold ?0.85 performs the best with accuracy = 0.987, \(F_{1}\) score = 0.906, and AUC \(=\) 0.968. We evaluated the performance of the proposed method on several Archive-It collections. The average precision of detecting off-topic pages in the collections is 0.89.  相似文献   
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6.
There is a pressing need to develop more effective therapeutics to fight cancer. An idyllic chemotherapeutic is expected to overcome drug resistance of tumors and minimize harmful side effects to healthy tissues. Antibody‐functionalized porous silicon nanoparticles loaded with a combination of chemotherapy drug and gold nanoclusters (AuNCs) are developed. These nanocarriers are observed to selectively deliver both payloads, the chemotherapy drug and AuNCs, to human B cells. The accumulation of AuNCs to target cells and subsequent exposure to an external electromagnetic field in the microwave region render them more susceptible to the codelivered drug. This approach represents a targeted two‐stage delivery nanocarrier that benefits from a dual therapeutic action that results in enhanced cytotoxicity.  相似文献   
7.
A growing trend within nanomedicine has been the fabrication of self‐delivering supramolecular nanomedicines containing a high and fixed drug content ensuring eco‐friendly conditions. This study reports on green synthesis of silica nanoparticles (Si‐NPs) using Azadirachta indica leaves extract as an effective chelating agent. X‐ray diffraction analysis and Fourier transform‐infra‐red spectroscopic examination were studied. Scanning electron microscopy analysis revealed that the average size of particles formed via plant extract as reducing agent without any surfactant is in the range of 100–170 nm while addition of cetyltrimethyl ammonium bromide were more uniform with 200 nm in size. Streptomycin as model drug was successfully loaded to green synthesised Si‐NPs, sustain release of the drug from this conjugate unit were examined. Prolong release pattern of the adsorbed drug ensure that Si‐NPs have great potential in nano‐drug delivery keeping the environment preferably biocompatible, future cytotoxic studies in this connection is helpful in achieving safe mode for nano‐drug delivery.Inspec keywords: silicon compounds, nanofabrication, nanomedicine, drug delivery systems, nanoparticles, X‐ray diffraction, Fourier transform infrared spectra, scanning electron microscopyOther keywords: nanosilica, streptomycin, nanoscale drug delivery, nanomedicine, silica nanoparticles, Azadirachta indica leaves extract, X‐ray diffraction analysis, Fourier transform‐infrared spectroscopy, scanning electron microscopy, cetyltrimethyl ammonium bromide, SiO2   相似文献   
8.
To grapple with multidrug resistant bacterial infections, implementations of antibacterial nanomedicines have gained prime attention of the researchers across the globe. Nowadays, zinc oxide (ZnO) at nano‐scale has emerged as a promising antibacterial therapeutic agent. Keeping this in view, ZnO nanostructures (ZnO‐NS) have been synthesised through reduction by P. aphylla aqueous extract without the utilisation of any acid or base. Structural examinations via scanning electron microscopy (SEM) and X‐ray diffraction have revealed pure phase morphology with highly homogenised average particle size of 18 nm. SEM findings were further supplemented by transmission electron microscopy examinations. The characteristic Zn–O peak has been observed around 363 nm using ultra‐violet–visible spectroscopy. Fourier‐transform infrared spectroscopy examination has also confirmed the formation of ZnO‐NS through detection of Zn–O bond vibration frequencies. To check the superior antibacterial activity of ZnO‐NS, the authors'' team has performed disc diffusion assay and colony forming unit testing against multidrug resistant E. coli, S. marcescens and E. cloacae. Furthermore, protein kinase inhibition assay and cytotoxicity examinations have revealed that green fabricated ZnO‐NS are non‐hazardous, economical, environmental friendly and possess tremendous potential to treat lethal infections caused by multidrug resistant pathogens.Inspec keywords: nanomedicine, zinc compounds, II‐VI semiconductors, wide band gap semiconductors, nanoparticles, scanning electron microscopy, X‐ray diffraction, antibacterial activity, transmission electron microscopy, particle size, Fourier transform infrared spectra, ultraviolet spectra, visible spectra, enzymes, biochemistry, molecular biophysics, microorganisms, drugs, toxicology, bonds (chemical), semiconductor growth, nanofabrication, vibrational modesOther keywords: green synthesised zinc oxide nanostructures, Periploca aphylla extract, antibacterial potential, multidrug resistant pathogens, multidrug resistant bacterial infections, antibacterial nanomedicines, P. aphylla aqueous extract, structural examinations, scanning electron microscopy, X‐ray diffraction, pure phase morphology, homogenised average particle size, SEM, transmission electron microscopy, Fourier‐transform infrared spectroscopy, bond vibration frequency, antibacterial activity, disc diffusion assay, colony forming unit testing, S. marcescens, E. cloacae, E. coli, ultraviolet‐visible spectroscopy, protein kinase inhibition assay, cytotoxicity, lethal infections, ZnO  相似文献   
9.
Nature instigates researchers significantly in imitating to engender comparable properties using artificial methods, which unlocks developing trend in material science and engineering progress. Fabricating graded‐index nanostructures is an effective approach to tune and generate similar properties artificially such as the moth's eye antireflectance (AR) or lotus like superhydrophobicity. Herein, Bilayer AR coatings with periodically arranged SiO2 hierarchical nanostructures resembling moth eyes are fabricated on dense SiO2 matrix base layer using the versatile route of glancing angle deposition technique (GLAD). The refractive indices of monolayer SiO2 are tuned from 1.46 to 1.08 by changing the deposition angle (α) from 0 to 88°. The fabricated bilayer SiO2 AR (BSAR) film possess high optical omnidirectional broadband transparency and tunability at a desired wavelength range showing <1% reflectance. The present AR design is flexible and practically applicable to various supporting substrate materials (η varies from 1.45 to 1.9). Furthermore, the omnidirectional BSAR films show multiple functions including enhanced mechanical strength, the thermal stability (up to 300 °C), and hydrophobic capability with a water contact angle (CA) of 147° to withstand under humid environment. This multipurpose coating provides an intriguing route in optics field for imminent research.
  相似文献   
10.
The demand for cloud computing has increased manifold in the recent past. More specifically, on-demand computing has seen a rapid rise as organizations rely mostly on cloud service providers for their day-to-day computing needs. The cloud service provider fulfills different user requirements using virtualization - where a single physical machine can host multiple Virtual Machines. Each virtual machine potentially represents a different user environment such as operating system, programming environment, and applications. However, these cloud services use a large amount of electrical energy and produce greenhouse gases. To reduce the electricity cost and greenhouse gases, energy efficient algorithms must be designed. One specific area where energy efficient algorithms are required is virtual machine consolidation. With virtual machine consolidation, the objective is to utilize the minimum possible number of hosts to accommodate the required virtual machines, keeping in mind the service level agreement requirements. This research work formulates the virtual machine migration as an online problem and develops optimal offline and online algorithms for the single host virtual machine migration problem under a service level agreement constraint for an over-utilized host. The online algorithm is analyzed using a competitive analysis approach. In addition, an experimental analysis of the proposed algorithm on real-world data is conducted to showcase the improved performance of the proposed algorithm against the benchmark algorithms. Our proposed online algorithm consumed 25% less energy and performed 43% fewer migrations than the benchmark algorithms.  相似文献   
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