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1.
Effects of fullerenes and single-wall carbon nanotubes on murine and human macrophages 总被引:2,自引:0,他引:2
The discovery in 1985 of C-fullerenes, a novel carbon allotrope with a polygonal structure made up solely by 60 carbon atoms, and in 1991 of C-nanotubes, thin carbon filaments (1-3 μm in length and 0.001 μm in diameter) with extraordinary mechanical properties, opened a wide field of activity in carbon research. While toxicity and biocompatibility of C-fullerenes have been widely investigated, literature data concerning the biological properties and biotoxicity of C-nanotubes are poor and contradictory. Here we test the ability of highly purified C-Single-Walled-Nanotubes (SWNTs) and C-fullerenes to elicit an inflammatory response by murine and human macrophage cells in vitro. In order to determine the potential of these C-derivatives as biological inducers of inflammatory reactions we evaluate the ability of C-single-walled nanotubes and C-fullerenes to induce the release of NO by murine macrophages cells, to stimulate the phagocytic activity of human macrophage cells and to be cytotoxic against these cells. We show that SWNTs-C-nanotubes, when highly purified, as well as C-fullerenes, do not stimulate the release of NO by murine macrophage cells in culture, their uptake by human macrophage cells is very low, and they possess a very low toxicity against human macrophage cells. 相似文献
2.
Serafino Teseo Emmanuel Lecoutey Daniel J. C. Kronauer Abraham Hefetz Alain Lenoir Pierre Jaisson Nicolas Châline 《Journal of chemical ecology》2014,40(5):429-438
Although cuticular hydrocarbons (CHCs) have received much attention from biologists because of their important role in insect communication, few studies have addressed the chemical ecology of clonal species of eusocial insects. In this study we investigated whether and how differences in CHCs relate to the genetics and reproductive dynamics of the parthenogenetic ant Cerapachys biroi. We collected individuals of different ages and subcastes from several colonies belonging to four clonal lineages, and analyzed their cuticular chemical signature. CHCs varied according to colonies and clonal lineages in two independent data sets, and correlations were found between genetic and chemical distances between colonies. This supports the results of previous research showing that C. biroi workers discriminate between nestmates and non-nestmates, especially when they belong to different clonal lineages. In C. biroi, the production of individuals of a morphological subcaste specialized in reproduction is inversely proportional to colony-level fertility. As chemical signatures usually correlate with fertility and reproductive activity in social Hymenoptera, we asked whether CHCs could function as fertility-signaling primer pheromones determining larval subcaste fate in C. biroi. Interestingly, and contrary to findings for several other ant species, fertility and reproductive activity showed no correlation with chemical signatures, suggesting the absence of fertility related CHCs. This implies that other cues are responsible for subcaste differentiation in this species. 相似文献
3.
Weighted walkthroughs are a quantitative model for representing the spatial relation between two raster features in image databases. In this paper, we establish a correspondence between the weighted walkthroughs and qualitative models for spatial reasoning. We provide rules for estimating qualitative geometric properties and topological relations from the quantitative data that are computed for each pair of pixel sets. The approach has been tested through experiments with raster regions. 相似文献
4.
Pasqua D’Ambra Daniela di Serafino Salvatore Filippone 《Computers & Mathematics with Applications》2013,65(3):352-361
We present a comparative study of parallel Schwarz preconditioners in the solution of linear systems arising in a Large Eddy Simulation (LES) procedure for turbulent plane channel flows. This procedure applies a time-splitting technique to suitably filtered Navier–Stokes equations, in order to decouple the continuity and momentum equations, and uses a semi-implicit scheme for time integration and finite volumes for space discretisation. This approach requires the solution of four sparse linear systems at each time step, accounting for a large part of the overall simulation; hence the linear system solvers are a crucial component in the whole procedure. Several preconditioners are applied in the simulation of a reference test case for the LES community, using discretisation grids of different sizes, with the aim of analysing the effects of different algorithmic choices defining the preconditioners, and identifying the most effective ones for the selected problem. The preconditioners, coupled with the GMRES method, are run within SParC-LES, a recently developed LES code based on the PSBLAS and MLD2P4 libraries for parallel sparse matrix computations and preconditioning. 相似文献
5.
6.
Retreatment of silicon slurry by membrane processes 总被引:1,自引:0,他引:1
Testa F Coetsier C Carretier E Ennahali M Laborie B Serafino C Bulgarelli F Moulin P 《Journal of hazardous materials》2011,192(2):440-450
The purpose of the present study is to develop a process to regenerate the polish liquid used in Chemical and Mechanical Polishing (CMP), called “slurry”, and more specifically Silicon CMP slurry. Physico-chemical analyses show a considerable dilution of slurry through washing waters used in polishing. Thus, this effluent has been characterised for a better identification of the deviations from the slurry of reference (Point Of Use). Hence, the principle is to regenerate this effluent by membrane processes. The ultrafiltration results obtained at laboratory scale have led to the development of an industrial prototype. An optimal utilisation of this treatment allows completing a two-step process: the reconcentration by ultrafiltration and a chemical adjustment by addition of concentrated slurry. A stable behaviour of the slurry at the different steps of the process has been observed. Polishing results are similar with retreated and POU slurries. Furthermore, the functioning at industrial scale permits to maintain the performances obtained on the laboratory pilot. 相似文献
7.
Three-dimensional multipass SAR focusing: experiments with long-term spaceborne data 总被引:5,自引:0,他引:5
Fornaro G. Lombardini F. Serafino F. 《Geoscience and Remote Sensing, IEEE Transactions on》2005,43(4):702-714
Synthetic aperture radar (SAR) interferometry is a modern efficient technique that allows reconstructing the height profile of the observed scene. However, apart for the presence of critical nonlinear inversion steps, particularly crucial in abrupt topography scenarios, it does not allow one to separate different scattering mechanisms in the elevation (height) direction within the ground pixel. Overlay of scattering at different elevations in the same azimuth-range resolution cell can be due either to the penetration of the radiation below the surface or to perspective ambiguities caused by the side-looking geometry. Multibaseline three-dimensional (3-D) SAR focusing allows overcoming such a limitation and has thus raised great interest in the recent research. First results with real data have been only obtained in the laboratory and with airborne systems, or with limited time-span and spatial-coverage spaceborne data. This work presents a novel approach for the tomographic processing of European Remote Sensing satellite (ERS) real data for extended scenes and long time span. Besides facing problems common to the airborne case, such as the nonuniformly spaced passes, this processing requires tackling additional difficulties specific to the spaceborne case, in particular a space-varying phase calibration of the data due to atmospheric variations and possible scene deformations occurring for years-long temporal spans. First results are presented that confirm the capability of ERS multipass tomography to resolve multiple targets within the same azimuth-range cell and to map the 3-D scattering properties of the illuminated scene. 相似文献
8.
N Murugesan Z Gu PD Stein S Bisaha S Spergel R Girotra VG Lee J Lloyd RN Misra J Schmidt A Mathur L Stratton YF Kelly E Bird T Waldron EC Liu R Zhang H Lee R Serafino B Abboa-Offei P Mathers M Giancarli AA Seymour ML Webb JT Hunt 《Canadian Metallurgical Quarterly》1998,41(26):5198-5218
Substitution at the ortho position of N-(3,4-dimethyl-5-isoxazolyl) benzenesulfonamide led to the identification of the biphenylsulfonamides as a novel series of endothelin-A (ETA) selective antagonists. Appropriate substitutions on the pendant phenyl ring led to improved binding as well as functional activity. A hydrophobic group such as isobutyl or isopropoxyl was found to be optimal at the 4'-position. Introduction of an amino group at the 2'-position also led to improved analogues. Combination of the optimal 4'-isobutyl substituent with the 2'-amino function afforded an analogue (20, BMS-187308) with improved ETA binding affinity and functional activity. Compound 20 also has good oral activity in inhibiting the pressor effect caused by an ET-1 infusion in rats. Doses of 10 and 30 micromol/kg iv 20 attenuated the pressor responses due to the administration of exogenous ET-1 to conscious monkeys, indicating that the compound inhibits the in vivo activity of endothelin-1 in nonhuman primates. 相似文献
9.
10.
Lombardini F. Pardini M. Fornaro G. Serafino F. Verrazzani L. Costantini M. 《Radar, Sonar & Navigation, IET》2009,3(4):424-436
Three-dimensional (3-D) synthetic aperture radar (SAR) imaging is a recent technique, based on coherent SAR data combination, and aims to obtain a full 3-D analysis in space. It is a multibaseline extension of the SAR interferometry concept and offers new options for the analysis and monitoring of ground scenes by means of the capability of separating the scattering phenomena along the height dimension. In this work, the authors summarise and extend the results obtained by processing real ERS satellite urban data characterised by a long time span of acquisition and non-uniformly spaced satellite passes, comparing the performance in height focusing obtained with a singular value decomposition (SVD)-based method and adaptive beamforming. 相似文献