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Journal of Intelligent Manufacturing - In droplet-on-demand liquid metal jetting (DoD-LMJ) additive manufacturing, complex physical interactions govern the droplet characteristics, such as size,...  相似文献   
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Aim: The authors report the biological synthesis of zinc oxide nanoparticles (ZnO‐NPs) from the petals extract of Rosa indica L. (rose). Its efficacy was evaluated against two dermatophytes: namely: Trichophyton mentagrophytes and Microsporum canis which cause onychomycosis. The activity of antibiotics against the tested dermatophytes was enhanced, when evaluated in combination with ZnO‐NPs. Methods and results: The synthesised ZnO‐NPs were preliminary detected by using ultraviolet UV visible spectroscopy, which showed specific absorbance. The ZnO‐NPs were further characterised by nanoparticle tracking analysis (NTA), Fourier transform infrared spectroscopy (FTIR), transmission electron microscopy (TEM), X‐ray diffraction and Zetasizer. Moreover, nanoparticles containing nail paint (nanopaint) was formulated and its antifungal activity was also assessed against T. mentagrophytes and M. canis. ZnO‐NPs and formulated nanopaint containing ZnO‐NPs, both showed significant antifungal activity. The maximum activity was noted against M. canis and lesser against T. mentagrophytes. Minimum inhibitory concentration of ZnO‐NPs was also determined against the dermatophytes causing onychomycosis infection. Conclusion: ZnO‐NPs can be utilised as a potential antifungal agent for the treatment of onychomycosis after more experimental trials.Inspec keywords: diseases, zinc compounds, nanoparticles, nanofabrication, antibacterial activity, microorganisms, nanomedicine, ultraviolet spectra, visible spectra, Fourier transform infrared spectra, transmission electron microscopy, X‐ray diffraction, biomedical materials, patient treatmentOther keywords: zinc oxide nanoparticle biosynthesis, Rosa indica L petals extract, nail paint, antifungal activity evaluation, dermatophyte, Trichophyton mentagrophytes, Microsporum canis, antibiotics activity, ultraviolet‐visible spectroscopy, nanoparticle tracking analysis, Fourier transform infrared spectroscopy, transmission electron microscopy, X‐ray diffraction, zetasizer, antifungal agent, onychomycosis treatment  相似文献   
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Delay and cost overrun are common phenomena in projects worldwide. However, these are especially severe in developing countries. In India as per MOSPI report, 235 projects out of 410 were severely affected cost overrun due to certain factors. A short questionnaire was conducted with 15 prominent factors responsible for cost overrun and forwarded to 190 constructional professionals across India. Total 85 responses were received and it was analyzed using various statistical tools such as analysis of variance (ANOVA) and factor analysis tool using SPSS. In this study, top three factors affecting cost overruns were identified such as price escalation of raw material, delay in planned activity and lack of co-ordination between construction parties which could be significantly responsible for cost overnun of construction project in India. Factor analysis method was also carried out to group the factors into three components of overall questionnaire. These components, such as client control component, project management component, and contractor control component, would be useful to the various parties involved in the construction activities. This paper also provides suggestive frameworks which have been framed after discussing with large number of construction professionals or expert.  相似文献   
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Real-time data of reference evapotranspiration (ET0) at different space-time scales are essential to regional agricultural drought assessment, water accounting at the watershed to basin scale, and provide irrigation advisory to farmers. Here, we present a data-fusion approach that integrates satellite-based insolation product (8 km) from an Indian geostationary satellite (Kalpana-1) sensor (VHRR; Very High Resolution Radiometer) and high-resolution (~ 5 km) short-range weather forecast into an FAO56 model based on the classical Penman–Monteith (P-M) formulation. Five year (2009–2013) mean monthly estimates from the daily ET0 product over the Indian landmass were found to vary between 10 and 350 mm. It increased from January to May (70–350 mm), followed by a decrease to reach the lowest in November (10–140 mm), thus typically showing unimodal distribution. The comparison of daily space-based and station-based estimates (at six ground stations) produced a root mean square deviation (RMSD) ranging from 21% to 38% for 977 paired data sets with the correlation coefficient (r) varying from 0.32 to 0.82. The error was reduced from 25% to 10% with an increase in ‘r’ from 0.43 to 0.98 for daily to 10 day summation period. Spatial grid-to-grid comparison of monthly ET0 estimates with Global Data Assimilation System (GDAS) potential evapotranspiration (PET) showed RMSD within a range of 1.4–18.4% for most of the months, except for two. Further ET0 analysis over normal and drought years showed that it could be used for comprehensive drought assessment with other existing indicators.  相似文献   
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As the biofuel industry is heavily depend on technological advancement to remain competent, creation of new process techniques becomes inevitable to replace the existing under-performed operations. Mixing in the reactor requires enormous amount of energy to achieve required homogeneity. Reduction in the energy consumption and ultimately the cost of the product is possible by devising smart mixing strategies. In this review, interactions of mixing and reaction kinetics of enzymatic hydrolysis, fermentation, and cellulosic depolymerization in ionic solvents are discussed. When the processes are operated under various mixing conditions, changes in the reaction kinetics and dynamics of the processes occur. Therefore, analyzing the mixing effects at various levels (micro to macro) is crucial to decide best operating mixing conditions that drive the reaction kinetics toward the increased product yield. The review is helpful to identify a suitable mixing strategy that maximizes the production of biofuels—ethanol, 5-hydroxymethylfurfural, etc.  相似文献   
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Multifluid model (MFM) simulations have been carried out on liquid–solid fluidized beds (LSFB) consisting of binary and higher-order polydisperse particle mixtures. The role of particle–particle interactions was found to be as crucial as the drag force under laminar and homogenous LSFB flow regimes. The commonly used particle–particle closure models are designed for turbulent and heterogeneous gas–solid flow regimes and thus exhibit limited to no success when implemented for LSFB operating under laminar and homogenous conditions. A need is perceived to carry out direct numerical simulations of liquid–solid flows and extract data from them to develop rational closure terms to account for the physics of LSFB. Finally, a recommendation flow regime map signifying the performance of the MFM has been proposed. This map will act as a potential guideline to identify whether or not the bed expansion characteristics of a given polydisperse LSFB can be correctly simulated using MFM closures tested.  相似文献   
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Sugarcane juice is a very popular drink in India and other Asian countries, where sugarcane is an important crop. Since sugarcane juice spoils very quickly and there is a lack of research in this area, no commercialized sugarcane juices are available in India. Here, stabilized sugarcane juice was developed using response surface methodology. Total soluble solids, reducing sugar, total sugar, polyphenol oxidase activity, ascorbic acid, pH, optical density, transmittance, titrable acidity, microbiological properties, and sensory scores of the stabilized juice were evaluated using a Box–Behnken design. The composition was optimized and the sugarcane drink was further processed using blending and hot filling techniques. The processed juice was hot-filled into glass bottles under aseptic conditions. The predicted shelf life of the processed sugarcane juice was 3 months at 18 °C and 6 months at 10 °C.  相似文献   
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