Material Control System for the Manufactured Housing Industry

A manufactured home is a factory-built house constructed in a controlled factory environment according to federal standards known as the Department of Housing and Urban Development (HUD) code. The manufactured home shares approximately 20% of the total housing units in the United States and plays an important role in providing affordable housing. However, in terms of material engineering, advanced techniques are scarcely used in the manufactured housing (MH) industry. The current material flow and control systems are characterized as independent demand systems that are based on the personal experience of the material managers. Although independent inventory control systems are widely used in many manufacturing industries, these systems lead to a large amount of inventory and have many drawbacks for the MH industry. On the other hand, dependent inventory systems can reduce unfavorable inventory levels using new techniques and present substantial benefits for the MH industry. This paper applies lean inventory control systems and supply chain management techniques to the current systems of the MH industry and proposes a new framework of material control systems as one of the system management tools.     

Review of Life-Cycle Assessment Applications in Building Construction

Life-cycle assessment (LCA) has been used to assess product development processes “from cradle to grave” for many years. With the current push toward sustainable construction, LCA has gained importance as an objective method to evaluate the environmental impact of construction practices. A substantial amount of construction-related LCA work has been published recently; however, most of this work has been fragmented and a systematic compilation of this literature has not been undertaken. This article presents a structured review of building construction-related LCA literature, classified under four categories: LCA applications for construction products selection; LCA applications for construction systems/process evaluation; LCA tools and databases related to the construction industry; and LCA methodological developments related to the construction industry. Current challenges for using LCA in construction are discussed and potential areas for future research are highlighted. This review and similar efforts may provide the construction industry and associated researchers the necessary background to make better-informed construction decisions and assist the development of an agenda for further research.     

Manufactured Housing Production Layout Design

This paper presents exploratory research work in facility layout design of a manufactured housing production plant. Manufactured homes are built in a factory on an assembly line that consists of activity stations, subactivity stations, feeder stations, and storage areas. This research developed systematic process steps for the layout design of manufactured housing production plants with a qualitative approach. The qualitative approach takes into account space requirements and proximity parameters. For this purpose, the tools and techniques available in industrial and manufacturing engineering were investigated. Data related to the space and proximity requirements in the two case study production plants were collected, and alternative layouts were developed. These layouts were analyzed to suggest the best possible layout. Finally, layout design steps for the qualitative analysis of the facility design were presented in the form of a process flowchart.     

Synthetic Arabinomannan Heptasaccharide Glycolipids Inhibit Biofilm Growth and Augment Isoniazid Effects in Mycobacterium smegmatis

Biofilm formation, involving attachment to an adherent surface, is a critical survival strategy of mycobacterial colonies in hostile environmental conditions. Here we report the synthesis of heptasaccharide glycolipids based on mannopyranoside units anchored on to a branched arabinofuranoside core. Two types of glycolipids—2,3‐branched and 2,5‐branched—were synthesized and evaluated for their efficacies in inhibiting biofilm growth by the non‐pathogenic mycobacterium variant Mycobacterium smegmatis. Biofilm formation was inhibited at a minimum biofilm growth inhibition concentration (MBIC) of 100 μg mL^?1 in the case of the 2,5‐branched heptasaccharide glycolipid. Further, we were able to ascertain that a combination of the drug isoniazid with the branched heptasaccharide glycolipid (50 μg mL^?1) potentiates the drug, making it three times more effective, with an improved MBIC of 30 μg mL^?1. These studies establish that synthetic glycolipids not only act as inhibitors of biofilm growth, but also provide a synergistic effect when combined with significantly lowered concentrations of isoniazid to disrupt the biofilm structures of the mycobacteria.     

Changes in rat alveolar macrophageal antioxidant defense and reactive oxygen species release by high dietary vitamin E

For the past decade there has been emphasis on the immunomodulatory effects of vitamin E apart from its established role as a free radical scavenger. In alveolar macrophages (AMs), the role of vitamin E supplementation has not yet been investigated sufficiently. In the present study we have evaluated the effects of high vitamin E (DL-alpha-tocopheryl acetate, alpha-TA) supplementation for 10 d on rat-alveolar macrophageal antioxidant defense and reactive oxygen species (ROS) release. There was an increase in plasma vitamin E content from 5.22 +/- 1.30, at 50 mg to 12.23 +/- 1.06 and 22.32 +/- 2.02 micrograms/mL at 250 and 1,250 mg alpha-TA/kg dietary supplementation. Alveolar macrophage-vitamin E content enhanced by 56 to 75% at 250 and 1,250 mg alpha-TA diet as compared with control diet. Superoxide dismutase activity decreased and catalase and glutathione peroxidase activities increased significantly in AMs of 250 and 1,250 mg alpha-TA diet-fed rats. Reduced glutathione, total glutathione, and glutathione-S-transferase activity in AMs did not change significantly at any of the high doses of alpha-TA supplementation. On stimulation of AMs by phorbol-12-myristate-13-acetate (PMA), there was 2.8- and 3.5-fold enhancement in superoxide (O2-.) and H2O2 production, respectively, at 50 mg alpha-TA dose. But this increase by PMA could not take place in AMs from animals supplemented with 250 and 1,250 mg alpha-TA. It may therefore be concluded that high alpha-TA supplementation in diet may equip the AMs with a stronger defense against oxygen-free radical mediated damage to them.     

Material Flow-Based Facility Layout Analysis of a Manufactured Housing Production Plant

The layout of an assembly line type production plant can be designed or evaluated based on multiple criteria including, qualitative and/or quantitative aspects according to Mehrotra et al. in 2005. This paper presents the process of quantitative modeling and evaluation of the facility layout alternatives of a manufactured housing plant based on the material flow aspect. Manufactured homes are built on an assembly line similar to other manufactured products. However, production process, facility layout, and material handling system of the manufactured housing industry in the United States are still primitive as compared to automobile or other technologically advanced manufacturing facilities. In many of the manufactured housing factories, the facility layouts are inefficient because the stations are arranged without any prior planning and evaluation. The facility layout technologies in industrial engineering are used to develop an efficient facility layout for a manufactured housing plant. A manufactured housing plant was used as a case study plant. A material-flow based quantitative model was developed and implemented in a facility layout evaluation software program, FACTORYFLOW by EDS in 2002. The software was used to analyze the impact of material-flow on the facility layout of the case study plant and to develop alternatives. These layout alternatives were evaluated based on the feasibility and the projected cost savings. The analysis results indicated that many alternatives will result in cost savings as compared to existing layout. Once the alternatives were generated and evaluated, the comprehensive process steps for evaluating the facility layout alternatives based on the material-flow were developed in the form of a process flow diagram.     

Studies of Partial Molar Volumes of Some Narcotic-Analgesic Drugs in Aqueous-Alcoholic Mixtures at 25°C

Partial molar volumes of the drugs Parvon Spas, Parvon Forte, Tramacip, and Parvodex in aqueous mixtures of methanol (MeOH), ethanol (EtOH), and propan-1-ol (1-PrOH) have been determined. The data have been evaluated using the Masson equation. The parameters, apparent molar volumes , partial molar volumes , and S _v values (experimental slopes) have been interpreted in terms of solute–solvent interactions. In addition, these studies have also been extended to determine the effect of these drugs on the solvation behavior of an electrolyte (sodium chloride), a surfactant (sodium dodecyl sulfate), and a non-electrolyte (sucrose). It can be inferred from these studies that all drug cations can be regarded as structure makers/promoters due to hydrophobic hydration. Furthermore, the results are correlated to understand the solution behavior of drugs in aqueous-alcoholic systems, as a function of the nature of the alcohol and solutes.     

DiGVis: A system for comprehension and creation of directed graphs for the visually challenged

One of the major barriers for the social inclusion of blind persons is the limited access to graphics-based learning resources which are highly vision oriented. This paper presents a cost-effective tool which facilitates comprehension and creation of virtual directed graphs, such as flowcharts, using alternate modalities of audio and touch. It provides a physically accessible virtual spatial workspace and multimodal interface to non-visually represent directed graphs in interactive manner. The concept of spatial query is used to aid exploration and mental visualization through audio and tactile feedback. A unique aspect of the tool, named DiGVis, offers compatible representations of directed graphs for the sighted and non-sighted persons. A study with 28 visually challenged subjects indicates that the tool facilitates comprehension of layout and directional connectivity of elements in a virtual diagram. Further, in a pilot study, blind persons could independently comprehend a virtual flowchart layout and its logical steps. They were also able to create the flowchart data without sighted assistance using DiGVis. A comparison with sighted subjects using DiGVis for similar task demonstrates the effectiveness of the technique for inclusive education.     

Internal relationship modeling and production planning optimization for the manufactured housing

The ‘manufacturer-internal relationship optimization model (MIROM)’, a schematic framework for internal relationship, is proposed for the manufactured housing (MH) factory. This model emphasizes the relationship between customer order from retailers (i.e., customized MH) and the production process, indicating that these elements are not mutually exclusive. In particular, through surveys and site visits, the planning of the product mix and sequence in the MH factory is considered the most critical area of the MIROM framework. This paper aims to convey how these areas can be elevated to the planning level with innovative changes and optimization. A product mix optimization model with linear programming was developed and a sequence optimization model was created by incorporating just-in-time (JIT) approaches. The proposed strategic MIROM framework and the specific optimization models can contribute to achieving significant improvement in the internal MH production planning. It can be applied for the site-built housing industry with similar industrialized environments depending on the scale of the operation.