排序方式: 共有19条查询结果,搜索用时 15 毫秒
1.
DOE applied to multi-response optimisation study on performance,combustion and emission characteristics of a VCR diesel engine 总被引:1,自引:0,他引:1
Syed Azam Pasha Quadri M. Masood Tabish Wahidi Mohd Ghouse Sundkey Mohd Wajid 《国际自然能源杂志》2017,38(8):759-764
There are various parameters which may influence the IC engine performance. The trial and error method is a technique used to identify the best parameters. However, this method demands extensive experimental work and results in a great waste of time and resources. Thus, the design of experiments (DOEs) developed by Taguchi is employed. The multi-responses which need to be maximised are brake thermal efficiency, mechanical efficiency, cylinder pressure and cumulative heat release rate, whereas the responses which are to be minimised are specific fuel consumption, oxides of nitrogen and carbon monoxide. In the present study, an optimised DOE(L9) orthogonal array based on the Taguchi statistical method was formulated and a series of experiments were conducted under controlled supervision by considering three different injection operating pressures (IOPs) (200, 220 and 240 bar) and three different compression ratios (CRs) (16.5, 17.5 and 18.5). The main objective of this paper is to find the best suited IOP and CR values which obtain higher performance, better combustion and lower emissions. 相似文献
2.
Sitara Afzal Muazzam Maqsood Irfan Mehmood Muhammad Tabish Niaz Sanghyun Seo 《计算机、材料和连续体(英文)》2021,66(3):2301-2315
Cerebral Microbleeds (CMBs) are microhemorrhages caused by certain abnormalities of brain vessels. CMBs can be found in people with Traumatic Brain Injury (TBI), Alzheimer’s disease, and in old individuals having a brain injury. Current research reveals that CMBs can be highly dangerous for individuals having dementia and stroke. The CMBs seriously impact individuals’ life which makes it crucial to recognize the CMBs in its initial phase to stop deterioration and to assist individuals to have a normal life. The existing work report good results but often ignores false-positive’s perspective for this research area. In this paper, an efficient approach is presented to detect CMBs from the Susceptibility Weighted Images (SWI). The proposed framework consists of four main phases (i) making clusters of brain Magnetic Resonance Imaging (MRI) using k-mean classifier (ii) reduce false positives for better classification results (iii) discriminative feature extraction specific to CMBs (iv) classification using a five layers convolutional neural network (CNN). The proposed method is evaluated on a public dataset available for 20 subjects. The proposed system shows an accuracy of 98.9% and a 1.1% false-positive rate value. The results show the superiority of the proposed work as compared to existing states of the art methods. 相似文献
3.
The WWOX gene was initially discovered as a putative tumor suppressor. More recently, its association with multiple central nervous system (CNS) pathologies has been recognized. WWOX biallelic germline pathogenic variants have been implicated in spinocerebellar ataxia type 12 (SCAR12; MIM:614322) and in early infantile epileptic encephalopathy (EIEE28; MIM:616211). WWOX germline copy number variants have also been associated with autism spectrum disorder (ASD). All identified germline genomic variants lead to partial or complete loss of WWOX function. Importantly, large-scale genome-wide association studies have also identified WWOX as a risk gene for common neurodegenerative conditions such as Alzheimer’s disease (AD) and multiple sclerosis (MS). Thus, the spectrum of CNS disorders associated with WWOX is broad and heterogeneous, and there is little understanding of potential mechanisms at play. Exploration of gene expression databases indicates that WWOX expression is comparatively higher in the human cerebellar cortex than in other CNS structures. However, RNA in-situ hybridization data from the Allen Mouse Brain Atlas show that specific regions of the basolateral amygdala (BLA), the medial entorhinal cortex (EC), and deep layers of the isocortex can be singled out as brain regions with specific higher levels of Wwox expression. These observations are in close agreement with single-cell RNA-seq data which indicate that neurons from the medial entorhinal cortex, Layer 5 from the frontal cortex as well as GABAergic basket cells and granule cells from cerebellar cortex are the specific neuronal subtypes that display the highest Wwox expression levels. Importantly, the brain regions and cell types in which WWOX is most abundantly expressed, such as the EC and BLA, are intimately linked to pathologies and syndromic conditions in turn associated with this gene, such as epilepsy, intellectual disability, ASD, and AD. Higher Wwox expression in interneurons and granule cells from cerebellum points to a direct link to the described cerebellar ataxia in cases of WWOX loss of function. We now know that total or partial impairment of WWOX function results in a wide and heterogeneous variety of neurodegenerative conditions for which the specific molecular mechanisms remain to be deciphered. Nevertheless, these observations indicate an important functional role for WWOX in normal development and function of the CNS. Evidence also indicates that disruption of WWOX expression at the gene or protein level in CNS has significant deleterious consequences. 相似文献
4.
W. Q. Khan K. M. Deen K. M. Ghauri R. Ahmad T. Tabish S. Atiq H. Zaigham L. Ali 《工业材料与腐蚀》2012,63(11):992-996
Two alloys of varying contents of tantalum (Ta) and tin (Sn) were prepared and homogenized to evaluate their microstructural and electrochemical characteristics. The microstructural features were revealed through optical microscopy and X‐ray diffraction methods. The formation and stability of passive film was studied by open circuit potential, potentiodynamic polarization and electrochemical scratch tests. The electrochemical impedance spectroscopy results simulated with equivalent electrical circuit suggested bilayer structure of outer porous and inner barrier oxide films. The quantitative data showed thick inner barrier oxide film retarded electrochemical reactions at low ‘Ta’ and ‘Sn’ concentration. The increased percentage of ‘Ta’ and ‘Sn’ deteriorated barrier properties by agglomeration of Ta2Sn3 and Ta0.15Ti0.85 precipitates within grains and at the grain boundaries. 相似文献
5.
Nasser A. Al-Shabib Javed Masood Khan Ajamaluddin Malik Md. Tabish Rehman Fohad Mabood Husain Mohamed F. AlAjmi Osama Hamdan Ali Alghamdi Altaf Khan 《Journal of dairy science》2021,104(5):5141-5151
Amyloid fibril formation of proteins is associated with a number of neurodegenerative diseases. Several small molecules can accelerate the amyloid fibril formation in vitro and in vivo. However, the molecular mechanism of amyloid fibrillation is still unclear. In this study, we investigated how the food dye quinoline yellow (QY) induces amyloid fibrillation in α-lactalbumin (α-LA), a major whey protein, at pH 2.0. We used several spectroscopy techniques and a microscopy technique to explore how QY provokes amyloid fibrillation in α-LA. From turbidity and Rayleigh light scattering experiments, we found that QY promotes α-LA aggregation in a concentration-dependent manner; the optimal concentration for α-LA aggregation was 0.15 to 10.00 mM. Below 0.1 mM, no aggregation occurred. Quinoline yellow–induced aggregation was a rapid process that escaped the lag phase, but it depended on the concentrations of both α-LA and QY. We also demonstrated that aggregation switched the secondary structure of α-LA from α-helices to cross-β-sheets. We then confirmed the amyloid-like structure of aggregated α-LA by transmission electron microscopy measurements. Molecular docking and simulation confirmed the stability of the α-LA-QY complex due to the formation of 1 hydrogen bond with Lys99 and 2 electrostatic interactions with Arg70 and Lys99, along with hydrophobic interactions with Leu59 and Tyr103. This study will aid in our understanding of how small molecules induce aggregation of proteins inside the stomach (low pH) and affect the digestive process. 相似文献
6.
Farrukh Jamal Tabish Qidwai Prabhash K. Pandey Ranjan Singh Sangram Singh 《Catalysis communications》2011,12(13):1218-1223
In this study we investigated the decolorizing ability of Trichosanthes dioica-derived soluble peroxidase on structurally complex azo and anthraquinone dyes in the presence of redox mediators. Our results show that riboflavin acted as a better redox mediator than antraquinone-2, 6-disulfonate (AQDS). Riboflavin served as an efficient electron transferor than AQDS in the reduction of azo dyes, by contrast with anthraquinone dyes. Although the extent of decolorization (expressed as percent dye decolorization) varied from one dye to the other, maximum decolorization was achieved for the case when suspensions containing 0.45 EU (Enzyme Units)/ml and 0.2 mM riboflavin at pH 5.0 were incubated for 2 h at 40 °C. 相似文献
7.
Tabish Rohan Mancuso Renato Wasly Saud Pellizzoni Rodolfo Caccamo Marco 《Real-Time Systems》2019,55(4):850-888
Real-Time Systems - Multi-core processors have replaced single-core systems in almost every segment of the industry. Unfortunately, their increased complexity often causes a loss of temporal... 相似文献
8.
Real-Time Systems - The proliferation of multi-core, accelerator-enabled embedded systems has introduced new opportunities to consolidate real-time systems of increasing complexity. But the road to... 相似文献
9.
Shahbaz Tabish 《国际自然能源杂志》2018,39(4):317-322
The performance of a photovoltaic (PV) module varies with the change in its internal parameters, namely, series resistance, shunt resistance and ideality factor. They vary due to the manufacturing process involved as well as the material used to fabricate the PV system. For the performance to be as close to the ideal case, a model of the PV system has been used to simulate the performance of the various parameters. This paper presents the effects of variations in the performance of a PV module which occur due to the change in its parameters. One-diode model of a PV cell has been used to plot current–voltage and power–voltage characteristics of a 37-Wp solar module. 相似文献
10.
Amir Haider MuhibUr Rahman Tayyaba Khan Muhammad Tabish Niaz Hyung Seok Kim 《计算机、材料和连续体(英文)》2021,67(2):1747-1764
The 5G cellular network aims at providing three major services: Massive machine-type communication (mMTC), ultra-reliable low-latency communications (URLLC), and enhanced-mobile-broadband (eMBB). Among these services, the URLLC and eMBB require strict end-to-end latency of 1 ms while maintaining 99.999% reliability, and availability of extremely high data rates for the users, respectively. One of the critical challenges in meeting these requirements is to upgrade the existing optical fiber backhaul network interconnecting the base stations with a multigigabit capacity, low latency and very high reliability system. To address this issue, we have numerically analyzed 100 Gbit/s coherent optical orthogonal frequency division multiplexing (CO-OFDM) transmission performance over 400 km single-mode fiber (SMF) and 100 km of multi-mode fiber (MMF) links. The system is simulated over optically repeated and non-repeated SMF and MMF links. Coherent transmission is used, and the system is analyzed in a linear and non-linear regime. The system performance is quantified by bit error ratio (BER). Spectrally efficient and optimal transmission performance is achieved for 400 km SMF and 100 km MMF link. The results designate that MMF links can be employed beyond short reach applications by using them in the existing SMF infrastructure for long haul transmission. In particular, the proposed CO-OFDM system can be efficiently employed in 5G backhaul network. The multi-gigabit capacity and lower BER of the proposed system makes it a suitable candidate especially for the eMBB and URLLC requirements for 5G backhaul network. 相似文献