全文获取类型
收费全文 | 6022篇 |
免费 | 517篇 |
国内免费 | 3篇 |
专业分类
电工技术 | 35篇 |
综合类 | 4篇 |
化学工业 | 2001篇 |
金属工艺 | 49篇 |
机械仪表 | 119篇 |
建筑科学 | 223篇 |
矿业工程 | 7篇 |
能源动力 | 148篇 |
轻工业 | 1829篇 |
水利工程 | 34篇 |
石油天然气 | 38篇 |
无线电 | 229篇 |
一般工业技术 | 810篇 |
冶金工业 | 355篇 |
原子能技术 | 16篇 |
自动化技术 | 645篇 |
出版年
2024年 | 13篇 |
2023年 | 55篇 |
2022年 | 217篇 |
2021年 | 406篇 |
2020年 | 201篇 |
2019年 | 200篇 |
2018年 | 225篇 |
2017年 | 243篇 |
2016年 | 245篇 |
2015年 | 202篇 |
2014年 | 294篇 |
2013年 | 476篇 |
2012年 | 438篇 |
2011年 | 488篇 |
2010年 | 309篇 |
2009年 | 336篇 |
2008年 | 323篇 |
2007年 | 323篇 |
2006年 | 207篇 |
2005年 | 194篇 |
2004年 | 158篇 |
2003年 | 143篇 |
2002年 | 123篇 |
2001年 | 73篇 |
2000年 | 63篇 |
1999年 | 57篇 |
1998年 | 74篇 |
1997年 | 71篇 |
1996年 | 67篇 |
1995年 | 50篇 |
1994年 | 37篇 |
1993年 | 35篇 |
1992年 | 19篇 |
1991年 | 19篇 |
1990年 | 10篇 |
1989年 | 14篇 |
1988年 | 19篇 |
1987年 | 10篇 |
1986年 | 10篇 |
1985年 | 11篇 |
1984年 | 9篇 |
1983年 | 12篇 |
1982年 | 10篇 |
1981年 | 9篇 |
1980年 | 3篇 |
1979年 | 10篇 |
1978年 | 5篇 |
1977年 | 9篇 |
1976年 | 6篇 |
1975年 | 3篇 |
排序方式: 共有6542条查询结果,搜索用时 31 毫秒
1.
Raquel Cano Jos L. Prez Liss Angarita Dvila ngel Ortega Yosselin Gmez Nereida Josefina Valero-Cedeo Heliana Parra Alexander Manzano Teresa Isabel Vliz Castro María P. Díaz Albornoz Gabriel Cano Joselyn Rojas-Quintero Maricarmen Chacín Valmore Bermúdez 《International journal of molecular sciences》2021,22(9)
Non-alcoholic fatty liver disease (NAFLD) is considered the most common liver disorder, affecting around 25% of the population worldwide. It is a complex disease spectrum, closely linked with other conditions such as obesity, insulin resistance, type 2 diabetes mellitus, and metabolic syndrome, which may increase liver-related mortality. In light of this, numerous efforts have been carried out in recent years in order to clarify its pathogenesis and create new prevention strategies. Currently, the essential role of environmental pollutants in NAFLD development is recognized. Particularly, endocrine-disrupting chemicals (EDCs) have a notable influence. EDCs can be classified as natural (phytoestrogens, genistein, and coumestrol) or synthetic, and the latter ones can be further subdivided into industrial (dioxins, polychlorinated biphenyls, and alkylphenols), agricultural (pesticides, insecticides, herbicides, and fungicides), residential (phthalates, polybrominated biphenyls, and bisphenol A), and pharmaceutical (parabens). Several experimental models have proposed a mechanism involving this group of substances with the disruption of hepatic metabolism, which promotes NAFLD. These include an imbalance between lipid influx/efflux in the liver, mitochondrial dysfunction, liver inflammation, and epigenetic reprogramming. It can be concluded that exposure to EDCs might play a crucial role in NAFLD initiation and evolution. However, further investigations supporting these effects in humans are required. 相似文献
2.
Galli Carlo Sala Roberto Colangelo Maria Teresa Guizzardi Stefano 《Scientometrics》2022,127(7):3879-3910
Scientometrics - A literature search on the in vitro testing of anti-inflammatory compounds of natural origin revealed a considerable number of studies adopting a similar template for data... 相似文献
3.
Lucas Portela Oliveira Camila Cristina de Foggi Bruna Natália Alves da Silva Pimentel Marcelo Assis Juan Andrés Elson Longo Carlos Eduardo Vergani 《Ceramics International》2021,47(16):22604-22614
The present study reports for the first time the performance of silver phosphate (Ag3PO4) microcrystals as photocatalyst (degradation of Rodamine B-RhB) and antifungal agent (against Candida albicans–C. albicans) under visible-light irradiation (455 nm). Ag3PO4 microcrystals were synthesized by a simple co-precipitation (CP) method at room temperature. The structural and electronic properties of the as-synthetized Ag3PO4 have been investigated before and after 4 cycles of RhB degradation under visible light using X-ray diffraction (XRD), micro-Raman spectroscopy, UV–Vis spectrophotometer and field emission scanning electron microscopy (FE-SEM) images. The antifungal activity was analyzed in planktonic cells and 48h-biofilm of C. albicans by colony forming units (CFU) counting, confocal laser and FE-SE microscopies. Statistical analysis was carried out using SPSS software. Morphological and structural modifications of Ag3PO4 were observed upon recycling. After 4 recycles, the material maintained its photodegradation property; an eightfold increase in the efficiency of Ag3PO4 was observed in planktonic cells and a two fold increase in biofilm when irradiated under visible light. Thus, higher antifungal effectiveness against C. albicans was obtained when associated with visible-light irradiation. 相似文献
4.
Ana Clara Sabbione Santiago Suárez María Cristina Añón Adriana Scilingo 《International Journal of Food Science & Technology》2019,54(5):1506-1513
In this study, amaranth flour was used as an ingredient to prepare gluten-free cookies. The production process and attributes of amaranth cookies were characterised, and the potential use of amaranth flour as a functional ingredient was analysed. Cookies exhibited a non-uniform reddish brown colour and a cookie factor ratio of 4.5 ± 0.6. Storage studies indicated that after 3 weeks at room temperature cookies presented slight variations in the texture. Simulated gastrointestinal digestion of this product was able to release peptides capable of exerting potential antithrombotic and antihypertensive activities, IC50 values of 0.22 ± 0.04 and 0.23 ± 0.03 mg mL−1 protein, respectively. This work demonstrates for the first time that food made with amaranth flour exerts potential antithrombotic and antihypertensive activity. In conclusion, these amaranth cookies could be an alternative way of incorporating potentially health beneficial products for people who choose a conscious diet, including coeliac or vegan consumers. 相似文献
5.
Yana Jorge Polizer-Rocha José M. Lorenzo Daniel Pompeu Isabela Rodrigues Juliana Cristina Baldin Manoela A. Pires Maria Teresa A. Freire Francisco Jose Barba Marco Antonio Trindade 《International Journal of Food Science & Technology》2020,55(3):1018-1024
This study aimed to evaluate the physicochemical characteristics and sensory attributes of beef burgers with the addition of pea fibre as a partial substitute of meat or fat. Three formulations were prepared: control (CON) – similar to the commercial formulation; fibre/less meat (FLM)—5% meat reduction and addition of 1% pea fibre; fibre/less fat (FLF)—7% fat reduction and addition of 1% pea fibre. Non-significant differences were obtained for pH, colour parameters (L* and b*), texture profile, cooking loss and size reduction among formulations. Moreover, sensory analysis with consumers of beef burgers did not indicate differences among the formulations for all the analysed attributes. Therefore, pea fibre is a promising partial replacer for meat and fat in beef burgers due to the preservation of technological parameters and sensory acceptance. 相似文献
6.
7.
Cheese fortification using saturated monoglyceride self‐assembly structures as carrier of omega‐3 fatty acids
下载免费PDF全文
![点击此处可从《International Journal of Food Science & Technology》网站下载免费的PDF全文](/ch/ext_images/free.gif)
Sonia Calligaris Alexandra Ignat Marialuisa Biasutti Nadia Innocente Maria Cristina Nicoli 《International Journal of Food Science & Technology》2015,50(9):2129-2134
The purpose of this research was to study the capacity of emulsions containing saturated monoglyceride self‐assembly structures to deliver omega‐3 fatty acids in fresh soft cheese. To this aim, fortified emulsions containing different ratios of milk, saturated monoglycerides (MGs) and cod liver oil were added to milk before cheese‐making. These emulsions were characterised by distinct microstructural features observed by polarised light microscopy and apparent viscosity values. The omega‐3 delivery performance of MG emulsions highlighted that this strategy allowed a good retention of the omega‐3‐rich oil in the curd (up to 75%). The fortified cheeses showed yield value and fat content higher than those of control samples. The enriched cheese showed hardness and cohesiveness obtained by texture profile analysis similar to those of the unfortified product. Only a slight decrease in gumminess was detected in fortified cheese. 相似文献
8.
9.
Teresa Glomb Benita Wiatrak Katarzyna Gbczak Tomasz Gbarowski Dorota Bodetko aneta Czynikowska Piotr
witek 《International journal of molecular sciences》2020,21(23)
Numerous studies have confirmed the coexistence of oxidative stress and inflammatory processes. Long-term inflammation and oxidative stress may significantly affect the initiation of the neoplastic transformation process. Here, we describe the synthesis of a new series of Mannich base-type hybrid compounds containing an arylpiperazine residue, 1,3,4-oxadiazole ring, and pyridothiazine-1,1-dioxide core. The synthesis was carried out with the hope that the hybridization of different pharmacophoric molecules would result in a synergistic effect on their anti-inflammatory activity, especially the ability to inhibit cyclooxygenase. The obtained compounds were investigated in terms of their potencies to inhibit cyclooxygenase COX-1 and COX-2 enzymes with the use of the colorimetric inhibitor screening assay. Their antioxidant and cytotoxic effect on normal human dermal fibroblasts (NHDF) was also studied. Strong COX-2 inhibitory activity was observed after the use of TG6 and, especially, TG4. The TG11 compound, as well as reference meloxicam, turned out to be a preferential COX-2 inhibitor. TG12 was, in turn, a non-selective COX inhibitor. A molecular docking study was performed to understand the binding interaction of compounds at the active site of cyclooxygenases. 相似文献