Polarization multiplexing of diffractive elements with metal-stripe grating pixels

Diffractive elements with polarization multiplexing for the visible spectral region are demonstrated. The polarization-multiplexing property of the element is based on the polarization-dependent transmission characteristics of metal-stripe subwavelength period gratings. The proper dimensions of these gratings are estimated by rigorous calculations. The principle of polarization multiplexing by use of metal-stripe subwavelength period gratings is described for a diffractive element that has a binary amplitude transmission per polarization channel and is demonstrated by experimental results.     

Comparison of resonator-originated and external beam shaping

The spatial shaping of laser beams is a subject of research in modern optics. Recently the introduction of diffractive elements in laser resonators has offered an alternative to external beam-shaping optics by mode shaping within the resonator. We describe the specification of the laser resonator mirrors to obtain by means of internal mode shaping a desired beam outside the resonator. Modal discrimination of the modified resonator and the mirror alignment sensitivity is discussed. Basic features of resonator-originated and external beam shaping are compared.     

Design procedure for the primary circuit of the Konvoi plants

The loading data for the design and fatigue analyses of the primary system components are derived from the plant operating transients as specified in the Operational Manual, the accident analyses and from the external event requirements. The methods used, applicable codes and standards, and QA procedures produce a design concept that contains significant safety margins. Measurements conducted in pre-Konvoi plants and during commissioning of the Konvoi plants deliver additional verifications of the analyses.     

Otitis externa among users of private swimming pools

The purpose of this study was to detect risk factors for developing otitis externa (OE) with special regard to swimming in private pools in holiday houses. Data were collected in a retrospective case-control study from June to October in 1993 and over the same period in 1994. Patients who had OE diagnosed by a general practitioner were included. In 1993 controls were 134 guests from 27 holiday houses where nobody got o.e. during their stay. The number of cases was 35. In 1994 the design was changed so that controls were the 95 healthy inhabitants from the same houses as the 23 cases. The amounts of time spent in the pools and the total bacteria count in the water were significant risk factors for developing OE. Pseudomonas aeruginosa was found in 80% of the ear swabs of the casegroup. In 1993 30% and in 1994 83% of the pools fulfilled the requirements for public pools set by the Danish authorities.     

An example demonstrating the conservatism of pipe calculations using KTA safety standard 3201.2

The conservatism of the code calculation is demonstrated by using an example of a highly stressed pipe subject to internal pressure and a dynamic bending moment. For this reason the allowable code loadings are compared with the load carrying capacity, which is derived by realistic analysis (plastic strains) and experiment. The latter analysis is based on measured stress-strain curves of materials and stresses at which crack initiation occurs. The experiment shows that the pipe is capable of withstanding considerably higher loads than the code permits. The realistic analysis explains this discrepancy.     

Peptides and anxiety: a dose-response evaluation of pentagastrin in healthy volunteers

A large body of data suggest that brain cholecystokinin (CCK) systems are involved in the regulation of anxiety, and numerous studies have demonstrated that CCK-4, a CCKB agonist, reliably induces panic attacks in patients with panic disorder. Recently, pentagastrin, a commercially available CCKB agonist, has been reported to have similar anxiogenic properties. To further explore the utility of pentagastrin as a challenge agent and to determine whether its effects are dose-related, a dose-response study was conducted in ten healthy volunteers. Pentagastrin (0.2 microgram/kg, 0.6 microgram/kg and 1.0 microgram/kg) and inactive placebo were infused over one minute on four separate challenge days in a double-blind fashion. Subjects received pentagastrin while participating in a structured social interaction task. Repeated measures of anxiety, blood pressure, pulse, ACTH, and cortisol were taken at baseline and postinfusion. Pentagastrin administration led to increases in anxiety, pulse, ACTH, cortisol and physical symptoms of panic, in a dose-related manner. Participation in the social interaction task led to increases in measures of anxiety as well as increases in pulse and blood pressure. Few differences were found between the 0.2 microgram/kg dose of pentagastrin and placebo, or between the 0.6 microgram/kg and the 1.0 microgram/kg doses of pentagastrin. These findings support the notion that CCK systems are involved in the regulation of anxiety, and suggest that the 0.6 microgram/kg dose may be optimal for increasing symptoms of anxiety while minimizing unpleasant side effects. The powerful anxiogenic effects of the social interaction task underscore the importance of contextual variables in challenge studies.