A NEW PROCESS FOR THE EXTRACTION OF PENICILLIN G FROM THE FILTRATE OF FERMENTATION BROTH WITH TBP IN BUTYL ACETATE

The mixture of neutral phosphorus esters and butyl acetate (BA) can be used, as the extractant for the extraction of penicillin G. The extraction equilibrium pH can be increased to pH3—4 due to the stronger extraction capability of the solvent mixture, instead of pH1.8—2.2 with butyl acetate as solvent. The experimental results indicate that the total recovery of penicillin G can reach 96.6% with the new extraction process, which is 5—6% higher than that obtained with the traditional process using BA as solvent at pH1.8—2.2.     

醋酸丁酯及二正辛基亚砜萃取青霉素的研究

通过化学分析、计算机数据处理及FT—IR红外光谱的确证,提出了醋酸丁酯及二正辛基亚砜萃取青霉素的萃合反应式及萃合物的键合结构;研究中观察到青霉素在醋酸丁酯中形成了反胶团,胶团半径可达0.6μm.     

溶剂萃取法从氯化烟尘中提取钪

本文将一种新型萃取剂体系 P5709-N235-煤油应用于从氯化烟尘中提取钪的工艺。研究了影响钪回收的各种操作参数。其最佳工艺条件为:萃取剂1vol%P5709-1.1vol%N235-97.9vol%煤油,料液 pH0.8,O/A=1,室温;5mol/dm~3HCl,60℃反萃,O/A=1。可使 Sc~(3 )与 Fe~(3 )、Fe~(2 )、Ti~(4 )、Al~(3 )、Mn~(2 )、Ca~(2 )等完全分离,较好地解决了 Sc~(3 )-Fe~(3 )分离及分相慢等问题,具有较好的实用价值。     

用硫酸铝作絮凝剂从发酵滤液中萃取青霉素时破乳效果的研究

本文应用铝离子水溶液的化学特点及蛋白质在溶液中结构变化的特征,研究了用硫酸铝作为青霉素萃取工艺中的破乳剂的作用规律及操作条件.中、小试结果表明,先将硫酸铝溶液与滤液混合30秒,并使混合液的pH值>4.5,萃取平衡的pH值>3.0,0.1～0.3%(mass/v)的硫酸铝即可有较好的破乳效果,但需严格控制溶液的pH值.